Santo Tomas Vacations from $821
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest Santo Tomas vacation packages
Price found within the past 48 hours. Click for updated prices.
Punta Chame Club and Resort
Price was $1,111, price is now $821 per person
$821
per person
Aug 7 - Aug 14
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Panama City (PTY)
9.2/10 Wonderful! (5 reviews)
We Spent 15 days there and had a great time. It's in a great location.
Reviewed on Jan 2, 2020
Hotel Riu Plaza Panama
Bella Vista
Price was $1,575, price is now $1,042 per person
$1,042
per person
Jul 9 - Jul 15
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (5,456 reviews)
Great breakfast great gym perfect location comfortable beds quick elevators all is well!!!
Reviewed on May 29, 2026
Megapolis Hotel Panamá
San Francisco
Price was $1,439, price is now $1,027 per person
$1,027
per person
Jul 6 - Jul 10
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.4/10 Very Good! (1,528 reviews)
La habitación tenia una hermosa vista, muy limpia, desde nuestra llegada su personal fue correcta, amable y muy servicial, los desayunos fueron exquisitos a otro nivel y había de todo muy cerca de todo.
Reviewed on May 26, 2026
Casa Lefevre By Wynwood House
Casco Viejo
Price was $1,632, price is now $1,220 per person
$1,220
per person
Aug 12 - Aug 19
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.6/10 Exceptional! (14 reviews)
If you want to explore Casco Viejo, the location does not get any better than this. The balcony faces Cathedral Plaza and is a quick walk to many galleries, restaurants and clubs.
The apartment I was in had lots of charm and a great use of space. The check in and check out process was super easy. Also, the Wynwood team is always available on WhatsApp if there are any issues or if you need anything.
Reviewed on May 19, 2026
Don't see what you're looking for?
See all available trips from Columbus to Santo Tomas
View all tripsSanto Tomas Hotel Deals
Hotel Ciudad De David
Calle D Norte, Avenida 2da Este David Chiriqui
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $99 total per night from May 31 to Jun 1
$99 total
May 31 - Jun 1
Total with taxes and fees
9.4/10 Exceptional! (1,001 reviews)
"Staff always willing to help. Food reasonably priced in the restaurant. Maids excellent job!"
Reviewed on May 29, 2026
Aranjuez Hotel & Suites
Avenida Red Gray David Sur Chiriqui
$65 nightly
The price is $72 total per night from Jun 19 to Jun 20
$72 total
Jun 19 - Jun 20
Total with taxes and fees
9.2/10 Wonderful! (819 reviews)
"Clean room"
Reviewed on May 22, 2026
Hampton by Hilton David
Calle F Sur David Provincia d David Sur
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $97 total per night from Jun 6 to Jun 7
$97 total
Jun 6 - Jun 7
Total with taxes and fees
9.2/10 Wonderful! (565 reviews)
"Clean room"
Reviewed on May 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santo Tomas Vacation Packages
More vacations you might like
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
