São Tomé Vacations from $1,630

Book a Hotel + Flight or Car together to unlock savings

Photo by Toshiaki Yoshitake

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your São Tomé Vacation

Embark on your next thrilling adventure with a São Tomé vacation package, and leave knowing the finer details have been taken care of. And with the ability to tailor your escape, you know it'll be one to remember! São Tomé Island, Caue Ilheu Das Rolas and Ponta Figo are a few of the most popular cities here. Make sure your trip to São Tomé includes a visit to one or more of them! Expedia has everything you need for planning your São Tomé vacation. From flights and hotels, to activities and more, we're here to help you curate a travel experience like no other.

The Latest São Tomé vacation packages

Price found within the past 48 hours. Click for updated prices.
Praia Accommodation

Praia Accommodation

3 out of 5
Price was $1,700, price is now $1,630 per person
$1,630
per person
Jan 22 - Jan 26
found 1 day ago
Roundtrip flight included
Accra (ACC) to São Tomé Island (TMS)
7.2/10 Good! (17 reviews)
Hotel Praia

Hotel Praia

3.5 out of 5
Price was $1,830, price is now $1,734 per person
$1,734
per person
Jan 22 - Jan 26
found 1 day ago
Roundtrip flight included
Accra (ACC) to São Tomé Island (TMS)
7.6/10 Good! (17 reviews)
Pestana Miramar São Tomé

Pestana Miramar São Tomé

3 out of 5
Price was $1,706, price is now $1,638 per person
$1,638
per person
Jan 22 - Jan 26
found 1 day ago
Roundtrip flight included
Accra (ACC) to São Tomé Island (TMS)
7.2/10 Good! (44 reviews)
Very helpful and accommodating staff

Reviewed on Jun 7, 2024

Alojamento Santos Silva

Alojamento Santos Silva

3 out of 5
Price was $2,168, price is now $2,085 per person
$2,085
per person
Jan 22 - Jan 26
found 1 day ago
Roundtrip flight included
Accra (ACC) to São Tomé Island (TMS)
No reviews
Pestana São Tomé

Pestana São Tomé

5 out of 5
Vila Maria
Price was $1,834, price is now $1,775 per person
$1,775
per person
Jan 22 - Jan 26
found 1 day ago
Roundtrip flight included
Accra (ACC) to São Tomé Island (TMS)
8/10 Very Good! (73 reviews)
Wonderful stay, great staff, easy, relaxing delightful.

Reviewed on Dec 9, 2025

Don't see what you're looking for?
See all available trips from Columbus to São Tomé
View all trips

Discover the most popular places to visit in São Tomé

Estadio Nacional 12 de Julho

Catch an event at Estadio Nacional 12 de Julho during your trip to São Tomé. Wander the rainforest or discover the area's coral reefs.

Estadio Nacional 12 de Julho

Cathedral of São Tomé

4/5(1 review)

Cathedral of São Tomé is just one of the places to see in São Tomé, so why not enjoy the other things to explore during your travels? Wander the rainforest or discover the area's coral reefs.

Cathedral of São Tomé

Palácio dos Congressos

After visiting Palácio dos Congressos, make a plan to see the other sights and activities in São Tomé.

Palácio dos Congressos

What to do in São Tomé

sipson tours stp

sipson tours stp

$99
per adult
sipson tours stp
See all activities in São Tomé

São Tomé Hotel Deals

Pestana São Tomé

Pestana São Tomé

5 out of 5
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $224 total per night from Dec 17 to Dec 18
$224 total
Dec 17 - Dec 18
Total with taxes and fees
8/10 Very Good! (76 reviews)
Wonderful stay, great staff, easy, relaxing delightful.

Reviewed on Dec 9, 2025

Pestana São Tomé
Hotel Central

Hotel Central

3.5 out of 5
Rua de Angola São Tomé São Tomé
$56 nightly
The price is $65 total per night from Dec 19 to Dec 20
$65 total
Dec 19 - Dec 20
Total with taxes and fees
8/10 Very Good! (24 reviews)
On my last night, I was locked out and couldn't open the outside door to enter the hotel. I tried to contact the hotel using the phone number provided on Expedia, but it wasn't updated. As a result, I had to stay at a friend's house for the night.

Reviewed on Nov 7, 2024

Hotel Central
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto São Tomé
$207 nightly
The price is $239 total per night from Dec 13 to Dec 14
$239 total
Dec 13 - Dec 14
Total with taxes and fees
9.4/10 Exceptional! (62 reviews)
Staff was very friendly. Food was excellent. Room was clean and well kept.

Reviewed on Dec 4, 2025

Omali São Tomé – Principe Collection
See all 44 properties in São Tomé
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best São Tomé Vacation Packages

São Tomé Essential Information

Language
Portuguese
Currency
São Tomé and Príncipe dobras
Local Welcome
Olá
Local Goodbye
Adeus
Closest Airport
Sao Tome Intl. Airport (TMS)
Top Sights
Jale Beach, Ilheu das Rolas Beach and Pico São Tomé

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How to find the best São Tomé package deals?
Finding a cheap São Tomé package deal is a breeze with Expedia. After you've entered your preferred dates and destination under our "Packages" tab, set your budget, apply a couple of filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to view the most wallet-friendly São Tomé package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are typically lower.
When to book a vacation package to São Tomé?
Score incredible bargains by reserving your flights in advance with Expedia. If spontaneity is more your thing, snap up one of our last-minute deals for an impromptu São Tomé escape.
How to plan a trip to São Tomé?

  1. Choose when to travel: Check your diary and pack your bags. Your preferred time of year and the activities available will also help you decide when to escape to São Tomé.
  2. Plan your budget wisely: On top of the cost of your stay, you should factor in other expenses. These include food, transportation and flights. Also, put aside some extra funds for unexpected costs that may arise during your trip to São Tomé.
  3. Discover São Tomé using our trip planning tool: Gain insights into the top attractions and best properties for your trip to São Tomé. You can also save your favorite locations, collaborate with your group and manage your plans in one place.
  4. Decide how long to go away for: Now that you're up to speed on São Tomé, you can work out the perfect length of your vacation. Pull together a draft itinerary and give yourself enough time for all the things you want to do.
  5. Combine your hotel and flights: Epic destination, check. Length of stay, check. All that's left is to pick a São Tomé vacation package that brings all your bookings together.
  6. Book experiences or activities ahead of time: Whether it's a ticket to a big attraction or a walking tour, you won't have to worry about missing out on the highlights of São Tomé. Find all the exciting things to do in São Tomé, Água Grande in São Tomé with our dedicated activity guide.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.