Downtown, SC
Seneca
Visit Downtown
Stay near popular Downtown attractions
Downtown Hotel Deals
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
$101 nightly
The price is $112 total per night from Sep 4 to Sep 5
$112 total
Sep 4 - Sep 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,013 reviews)
"Enjoyed the stay, it was clean and would stay again"
Reviewed on Sep 1, 2026
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
$59 nightly
The price is $65 total per night from Sep 22 to Sep 23
$65 total
Sep 22 - Sep 23
Total with taxes and fees
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
$101 nightly
The price is $112 total per night from Sep 23 to Sep 24
$112 total
Sep 23 - Sep 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
$106 nightly
The price is $117 total per night from Sep 2 to Sep 3
$117 total
Sep 2 - Sep 3
Total with taxes and fees
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (1,011 reviews)
"Great restaurant and bar. Love the fire pit rooms are spacious and clean . Great location ."
Reviewed on Aug 31, 2026
Inn @ Clemson
1303 Tiger Blvd Clemson SC
$80 nightly
The price is $89 total per night from Sep 2 to Sep 3
$89 total
Sep 2 - Sep 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,002 reviews)
"I was overcharged."
Reviewed on Aug 30, 2026
Quality Inn Clemson near University
3430 Clemson Blvd Anderson SC
$53 nightly
The price is $59 total per night from Sep 30 to Oct 1
$59 total
Sep 30 - Oct 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Downtown
Find the best Downtown areas and neighborhoods for the activities you enjoy most.
Serenity Bay
Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.
Pine Ridge Point
While Pine Ridge Point isn't home to many top sights, South Beach and Lake Keowee are some notable places to visit nearby.
Indian Oaks
While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Keowee Reservoir.
Keowee Plantation
When in Keowee Plantation, you can plan a visit to Oconee County Library Seneca Branch and Keowee Reservoir, some noteworthy sights in the nearby area.
