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Sistine Chapel contributes greatly to the religious and social culture of this area. It's a nice spot to enjoy a moment of prayer during a busy travel itinerary.

This well-known house of prayer is located in the picturesque principality of Vatican. You'll need to pay an entry fee, but exploring Sistine Chapel is worth every cent! If you're ready for some more sightseeing, attractions like St. Peters Basilica, Roman Forum and Piazza Navona are within reach.

Compare 10,596 hotels close to Sistine Chapel with room rates, reviews, and availability. Most hotels are fully refundable.

Grand Hotel Olympic
Grand Hotel Olympic
4 out of 5
Via Properzio 2/a, Rome, RM, 193
The price is $262 per night from Apr 4 to Apr 5
$262
per night
Apr 4 - Apr 5
Stay at this 4-star hotel in Rome. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the helpful staff and the overall value in our ...
7/10 Good! (995 reviews)
"Very close to Vatican City and local restaurants that were not over charging due to the tourist area. Staff and service was excellent, always very attentive and helpful. The only thing is that the hotel has an ANT problem. When we got into our room, there was about 10 ants crawling over a table collecting ..."

Reviewed on Jan 25, 2023

Grand Hotel Olympic
Starhotels Michelangelo
Starhotels Michelangelo
4 out of 5
Via Della Stazione Di San Pietro 14, Rome, RM, 165
The price is $273 per night from Apr 11 to Apr 12
$273
per night
Apr 11 - Apr 12
Stay at this 4-star family-friendly hotel in Rome. Enjoy free WiFi, free parking, and breakfast. Our guests praise the helpful staff and the comfy rooms in our ...
9/10 Wonderful! (1,000 reviews)
"The place is beautiful and enjoyed its location and breakfast. I didn't not like the housekeeping as we needed toilet paper and requested it but never received it. Also not convenient that the A/C control is not available to guests."

Reviewed on Mar 28, 2023

Starhotels Michelangelo
Hotel Isa
Hotel Isa
4 out of 5
Via Cicerone 39, Rome, RM, 186
Fully refundableReserve now, pay when you stay
The price is $276 per night from Apr 6 to Apr 7
$276
per night
Apr 6 - Apr 7
Stay at this 4-star boutique hotel in Rome. Enjoy free WiFi, a rooftop terrace, and a 24-hour front desk. Our guests praise the bar and the helpful staff in ...
9.2/10 Wonderful! (997 reviews)
"Amazing hotel with the most helpful and friendly staff. The location is perfect you can walk anywhere from there. Restaurants and cafes in every corner."

Reviewed on Mar 28, 2023

Hotel Isa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Best Lodging Options Near Sistine Chapel

Hotel Adriatic
Hotel Adriatic
2 out of 5
Via Vitelleschi 25, Rome, RM, 00193
Hotel Adriatic
Starhotels Michelangelo
Starhotels Michelangelo
4 out of 5
Via Della Stazione Di San Pietro 14, Rome, RM, 165
Starhotels Michelangelo
Hotel Isa
Hotel Isa
4 out of 5
Via Cicerone 39, Rome, RM, 186
Hotel Isa
Grand Hotel Olympic
Grand Hotel Olympic
4 out of 5
Via Properzio 2/a, Rome, RM, 193
Grand Hotel Olympic
The Hive Hotel
The Hive Hotel
4 out of 5
Via Torino 6, Rome, Roma, 184
The Hive Hotel
Mama Shelter Roma
Mama Shelter Roma
4 out of 5
Via Luigi Rizzo 20, Rome, 136
Mama Shelter Roma
Hotel Prati
Hotel Prati
2 out of 5
Via Crescenzio 89, Rome, RM, 00193
Hotel Prati
Camplus San Pietro
Camplus San Pietro
Via di Villa Alberici 12, Rome, RM, 00165
Camplus San Pietro
MZ Hotel Rome
MZ Hotel Rome
3 out of 5
Via Della Trinita Dei Pellegrini 12, Rome, 00186
MZ Hotel Rome
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.