South San Antonio Vacations from $427

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Your South San Antonio Vacation

Your next great adventure is calling with a vacation package to South San Antonio. Excitement, fun and nothing but good times — you're sure to find it in this neighborhood. What to cross off your itinerary first? Nearby Baptist University of the Americas is one thing you can't miss during your trip to South San Antonio. Whatever your travel goals or the size of your budget, booking the ultimate South San Antonio vacation is quick and easy with Expedia.

The Latest South San Antonio Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Far West Side
$427
per person
Oct 29 - Nov 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Antonio (SAT)
9/10 Wonderful! (1,937 reviews)
Perfect 2 br suite for a couple of dove hunters

Reviewed on Sep 8, 2026

Hotel Contessa

Hotel Contessa

Downtown San Antonio
$743
per person
Nov 20 - Nov 25
found 22 hours ago
Roundtrip flight included
Denver (DEN) to San Antonio (SAT)
9/10 Wonderful! (3,885 reviews)
Great stay on business trip

Reviewed on Sep 8, 2026

The Evers House

The Evers House

Fredericksburg Historic District
Save 100% on your flight
$484
per person
Oct 30 - Nov 2
found 19 hours ago
Roundtrip flight included
Denver (DEN) to San Antonio (SAT)
9.2/10 Wonderful! (280 reviews)
The St. Anthony, A Luxury Collection Hotel, San Antonio

The St. Anthony, A Luxury Collection Hotel, San Antonio

Downtown San Antonio
$555
per person
Nov 6 - Nov 8
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Antonio (SAT)
8.8/10 Excellent! (1,005 reviews)
Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas

Far West Side
$910
per person
Nov 5 - Nov 8
found 22 hours ago
Roundtrip flight included
Denver (DEN) to San Antonio (SAT)
8.8/10 Excellent! (1,001 reviews)

Where to stay in South San Antonio

Find the best South San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about South San Antonio
A boat tour on a canal with a bridge in the background.

Downtown San Antonio

5 out of top 10 points of interest in this area

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

A city skyline reflected in a calm body of water, a bridge, and a sunset sky.

Uptown

While visiting Uptown, you might make a stop by sights like Marion Koogler McNay Art Museum and Quarry Golf Club.

An old church with a bell tower and arches, surrounded by greenery and a stone structure.

Far West Side

1 out of top 10 points of interest in this area

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

A cityscape with a prominent tower, a large body of water, and a sunset.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.

South San Antonio Hotel Deals

Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

150 E Houston St San Antonio TX
Fully refundableReserve now, pay when you stay
$171 nightly
$202 total
Sep 13 - Sep 14
Total with taxes and fees
9.4/10 Exceptional! (3,075 reviews)
"Very nice place . The river walk goes right next to it. It’s a few doors from the loop of the Riverwalk. Great building. Did not hear anyone. Room service was really good after a long day."

Reviewed on Sep 8, 2026

Hotel Valencia Riverwalk
Riverwalk Plaza

Riverwalk Plaza

100 Villita Street San Antonio TX
Fully refundableReserve now, pay when you stay
$95 nightly
$112 total
Sep 14 - Sep 15
Total with taxes and fees
Riverwalk Plaza
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

105 S Saint Marys Street San Antonio TX
Fully refundableReserve now, pay when you stay
$128 nightly
$151 total
Sep 13 - Sep 14
Total with taxes and fees
9.4/10 Exceptional! (5,246 reviews)
"Very nice stay! Will be coming back. Breakfast was good. Valet parking assistants were excellent! Perfect spot right in the Riverwalk."

Reviewed on Sep 8, 2026

Drury Plaza Hotel San Antonio Riverwalk
See all 4,686 properties in South San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Things to do

San Antonio: Discovery Tour at Natural Bridge Caverns

San Antonio: Discovery Tour at Natural Bridge Caverns

$33
per adult
98% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
San Antonio: Botanical Garden Admission Ticket

San Antonio: Botanical Garden Admission Ticket

$18
per adult
100% of travellers recommend
San Antonio: Botanical Garden Admission Ticket
Picture 5 for Activity San Antonio: Six Flags Fiesta Texas Admission Ticket

San Antonio: Six Flags Fiesta Texas Admission Ticket

$49
per adult
80% of travellers recommend
San Antonio: Six Flags Fiesta Texas Admission Ticket
See all activities in San Antonio
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.