Title: South San Antonio Vacation Packages 2026 from $399 | Expedia.com

[South San Antonio Travel Guide](https://expedia.com/San-Antonio-South-San-Antonio.dx6239233)[Hotels in South San Antonio](https://expedia.com/South-San-Antonio-San-Antonio-Hotels.0-n6239233-0.Travel-Guide-Filter-Hotels)[Flights to San Antonio](https://expedia.com/Cheap-Flights-To-San-Antonio.d178303.Travel-Guide-Flights)[Things to do in San Antonio](https://expedia.com/Things-To-Do-In-San-Antonio.d178303.Travel-Guide-Activities)[Car Rentals in South San Antonio](https://expedia.com/Car-Rentals-In-South-San-Antonio.d6239233.Car-Rental-Guide)

![](https://images.trvl-media.com/place/6239233/9ca1d5a7-68a0-4d23-8e8a-5ea45775bc75.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# South San Antonio Vacations from $399

## Book a Hotel + Flight or Car together to unlock savings

## Your South San Antonio Vacation

Your next great adventure is calling with a vacation package to South San Antonio. Excitement, fun and nothing but good times — you're sure to find it in this neighborhood. What to cross off your itinerary first? Nearby [Baptist University of the Americas](https://www.expedia.com/Baptist-University-Of-The-Americas-Southside.d6230457.Vacation-Attraction) is one thing you can't miss during your trip to South San Antonio. Whatever your travel goals or the size of your budget, booking the ultimate South San Antonio vacation is quick and easy with Expedia.

## The Latest South San Antonio Vacation Packages

Price found within the past 48 hours. Click for updated prices.

![La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/3b4d6808_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Medical Center District

$399

per person

Apr 28 - May 2

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to San Antonio (SAT)

8.4/10 Very Good! (3,214 reviews)

Hotel was clean , and staff were very friendly.

Reviewed on Mar 14, 2026

![The St. Anthony, A Luxury Collection Hotel, San Antonio](https://images.trvl-media.com/lodging/1000000/10000/8800/8789/d1d101fe_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### The St. Anthony, A Luxury Collection Hotel, San Antonio

Downtown San Antonio

Save 100% on your flight

$736

per person

Apr 28 - May 2

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to San Antonio (SAT)

8.8/10 Excellent! (1,004 reviews)

We recently stayed at The St. Anthony, a Luxury Collection Hotel, San Antonio, and the property itself is truly lovely. The history of the hotel is fascinating, and my kids especially enjoyed the haunted lore surrounding it—it added a fun and exciting element to our stay. Unfortunately, the service didn’t quite live up to the caliber the hotel promotes. Our room was immediately next to an elevator that appeared to be having mechanical issues, making quite a bit of noise throughout the night. I also had to make two separate requests for a rollaway bed before one was finally delivered. During room service, we ordered a bottle of champagne, which was brought to the room but no one offered to open it. We were unable to get it open ourselves and ultimately didn’t drink it. At checkout, I asked if it could be refunded since it had never been opened or used. The staff member did check with a supervisor but ultimately said that wasn’t possible. Another thing worth noting: there’s no refrigerator in the room and no ice machine on the floor. If you need ice, you have to request it to be brought up. I did appreciate the front desk letting us know this ahead of time. The rooms themselves are beautiful, but the overall hospitality experience was lacking. Throughout our stay, we didn’t encounter many smiles or welcoming interactions from staff. It felt like most of the attention was directed toward a convention or business group that was in-house, rather than the other guests staying a

Reviewed on Mar 11, 2026

![Signia by Hilton La Cantera Resort & Spa](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3840h2556x0y4-935acc4f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Signia by Hilton La Cantera Resort & Spa

La Cantera District

$870

per person

Jun 3 - Jun 7

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to San Antonio (SAT)

9/10 Wonderful! (1,031 reviews)

Overall good stay. Would definitely stay there again

Reviewed on Mar 9, 2026

![Club Wyndham La Cascada](https://images.trvl-media.com/lodging/3000000/2260000/2256200/2256185/31f5639b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Club Wyndham La Cascada

Downtown San Antonio

$828

per person

Apr 28 - May 2

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to San Antonio (SAT)

8.4/10 Very Good! (181 reviews)

My family and I had a lovely weekend. The view from my balcony was so beautiful and very peaceful. Overall wonderful stay!

Reviewed on Aug 22, 2025

![Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/a5ac356f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

Northwest Side

$465

per person

Jun 3 - Jun 7

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to San Antonio (SAT)

7.8/10 Good! (1,076 reviews)

Subject: Concern About How My Issue Was Handled Hello, I would like to share something that happened during my recent visit. I had been waiting patiently for an issue to be resolved with the elevator along with another customer. While we were waiting for help, Paul spoke to me in a way that felt embarrassing, especially because it happened in front of the other customer. I want to say that Liz later stepped in and helped resolve the issue after the fact, and I appreciate her assistance. She handled the situation kindly and helped bring it to a resolution. My concern is mainly about how I was addressed earlier in front of others. It was uncomfortable and discouraging. I simply hope that in the future situations like this can be handled with a little more understanding and privacy. Thank you for taking the time to read this and for considering my concern. Respectfully,

Reviewed on Mar 14, 2026

## Where to stay in South San Antonio

Find the best South San Antonio areas and neighborhoods for the activities you enjoy most. [Learn more about South San Antonio](https://expedia.com/San-Antonio-South-San-Antonio.dx6239233)

![Downtown - Riverwalk which includes heritage architecture, boating and a river or creek](https://images.trvl-media.com/place/800120/c427a760-8f08-4152-8ff2-5ee8720d9068.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Downtown San Antonio

4 out of top 10 points of interest in this area

4/5(9,525 area reviews)

 Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit. 

[Find hotel + flight trips in Downtown San Antonio](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Downtown%20San%20Antonio&DestID=800120&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Marion Koogler McNay Art Museum which includes art and interior views as well as an individual male](https://images.trvl-media.com/place/502610/f2b1df08-6a69-4feb-8248-be1130a68fb3.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Uptown

 While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum. 

[Find hotel + flight trips in Uptown](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Uptown&DestID=553248635974902947&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![SanAntonio_SanAntonioSeaWorld_502636_04](https://images.trvl-media.com/place/502636/21ddbcf6-e0f6-4e89-a158-96c7800472ba.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Far West Side

1 out of top 10 points of interest in this area

 While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club. 

[Find hotel + flight trips in Far West Side](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Far%20West%20Side&DestID=553248635975749416&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![River walk in San Antonio](https://images.trvl-media.com/place/553248635978913844/ef5a7faf-f6d9-4f7e-b325-ac477c5ad14d.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Medical Center District

4/5(155 area reviews)

 While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and Cinemark San Antonio 16\. 

[Find hotel + flight trips in Medical Center District](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Medical%20Center%20District&DestID=553248635978913844&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Famous American landmark - Alamo mission in downtown San Antonio, Texas, USA](https://images.trvl-media.com/place/6343068/f511f264-1622-41ec-949e-c6074dc12bcb.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Stone Oak

4.5/5(495 area reviews)

 Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town. 

[Find hotel + flight trips in Stone Oak](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Stone%20Oak&DestID=6343068&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

## South San Antonio Hotel Deals

![Sonesta ES Suites San Antonio Downtown Alamo Plaza](https://images.trvl-media.com/lodging/1000000/50000/41200/41122/2727a411_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Sonesta ES Suites San Antonio Downtown Alamo Plaza

425 Bonham San Antonio TX

Fully refundableReserve now, pay when you stay

$95 nightly

$112 total

Apr 15 - Apr 16

Total with taxes and fees

8.4/10 Very Good! (2,026 reviews)

Easy walk to historic sites and shopping.

Reviewed on Mar 14, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F15%2F2026&endDate=4%2F16%2F2026&selected=41122&PinnedHotelID=41122&HadPinnedHotel=true&regionId=6239233)

![Riverwalk Plaza](https://images.trvl-media.com/lodging/1000000/290000/288400/288321/ef3ca433_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Riverwalk Plaza

100 Villita Street San Antonio TX

Fully refundableReserve now, pay when you stay

$119 nightly

$141 total

Apr 5 - Apr 6

Total with taxes and fees

8/10 Very Good! (6,387 reviews)

The staff was nice, the room was clean, and great location by the riverwalk.

Reviewed on Mar 14, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=288321&PinnedHotelID=288321&HadPinnedHotel=true&regionId=6239233)

![Crockett Hotel](https://images.trvl-media.com/lodging/1000000/10000/1600/1534/2e90fb1e_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Crockett Hotel

320 Bonham San Antonio TX

Fully refundableReserve now, pay when you stay

$123 nightly

$146 total

Mar 31 - Apr 1

Total with taxes and fees

8.8/10 Excellent! (2,601 reviews)

It's a great location. The Alamo is right around the corner from the hotel. There is so many shops and restaurants within walking distance. We loved the location.

Reviewed on Mar 14, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F31%2F2026&endDate=4%2F1%2F2026&selected=1534&PinnedHotelID=1534&HadPinnedHotel=true&regionId=6239233)

[See all 4,552 properties in South San Antonio](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F16%2F2026&endDate=3%2F17%2F2026&regionId=6239233)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Kid Friendly Vacations

[](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

LGBTQ Friendly Vacations

[](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adventure Vacations

[](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click)

![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Where to go when

[](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Honeymoon Vacations

[](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Mountain Vacations

[](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Fishing Vacations

[](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adults Only Vacations

[](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Waterpark Vacations

[](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Scuba Diving Vacations

[](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Yoga Vacations

[](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Cheap Vacations

[](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Solo Vacations

[](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click)

### Discover the most popular places to visit in South San Antonio

![River Walk featuring night scenes and a river or creek](https://images.trvl-media.com/place/6125866/3223be4e-1629-469b-8357-69494f446850.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### River Walk

When you visit San Antonio, this neighborhood will keep you entertained for days, from morning coffee to an evening theater performance.

[](https://expedia.com/River-Walk-Downtown-San-Antonio.d6125866.Vacation-Attraction)

![Air Force Security Forces K-9 handler, and her military working dog, seek out drugs inside a training house.](https://images.trvl-media.com/place/6123039/95d1cd17-8d47-4796-b24c-1b4b3d191827.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Lackland Air Force Base

Lackland Air Force Base is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the entertainment venues and shops in this family-friendly area. 

[](https://expedia.com/Lackland-Air-Force-Base-San-Antonio.d6123039.Vacation-Attraction)

![Roller Coaster](https://images.trvl-media.com/place/502602/9aaf48be-94fb-4cf1-b3fd-b5ed3097ae79.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Six Flags Fiesta Texas

Enjoy the rides and games at Six Flags Fiesta Texas and see why this is a favorite theme park in San Antonio. Experience the entertainment choices and lively festivals in this family-friendly area. 

[](https://expedia.com/Six-Flags-Fiesta-Texas-La-Cantera-District.d502602.Vacation-Attraction)

### Things to do

![Picture 1 for Activity San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall](https://mediaim.expedia.com/localexpert/45944337/f9916752-5205-4d47-ab5e-ca5e810b82f3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall

$42

per adult

[](https://expedia.com/things-to-do/san-antonio-twisted-trails-zip-rails.a45944337.activity-details)

![San Antonio: Discovery Tour at Natural Bridge Caverns](https://mediaim.expedia.com/localexpert/45924866/ae1ec610-6c7d-4d01-9bfc-7afaa0ced022.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### San Antonio: Discovery Tour at Natural Bridge Caverns

$36

per adult

**98%** of travellers recommend

[](https://expedia.com/things-to-do/san-antonio-discovery-tour-at-natural-bridge-caverns.a45924866.activity-details)

![San Antonio: Fredericksburg Wineries Day Trip with Tastings](https://mediaim.expedia.com/localexpert/47789062/4170aa97-d51c-4fa8-98ed-4c33e202eecd.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### San Antonio: Fredericksburg Wineries Day Trip with Tastings

$179

per adult

**100%** of travellers recommend

[](https://expedia.com/things-to-do/san-antonio-fredericksburg-wineries-day-trip-with-tastings.a47789062.activity-details)

[See all activities in San Antonio](https://expedia.com/things-to-do/search?rid=6239233)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.