Photo by Michael Schuier

Find Hotels with Suites in Southeast Iowa from $71

Start date: Check-in selected.
To Date
End date: Check-out

Check availability on Southeast Iowa Hotels with Suites

Tonight
Dec 4 - Dec 5
Tomorrow
Dec 5 - Dec 6
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Top Southeast Iowa Hotels with Suites

Free daily on-the-go breakfast
AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant

2.0 star property
Mount Pleasant
8.4 out of 10, Very Good, (529)
"Friendly check in - clean room - good location "
United States
Tia
$76 nightly
The price is $85
Dec 7 - Dec 8
Total with taxes and fees
AmericInn by Wyndham Mount Pleasant
Grand Suite | City view
Nauvoo Temple House Hotel

Nauvoo Temple House Hotel

2.0 star property
Nauvoo
9.0 out of 10, Wonderful, (336)
"It was a nice historic place to stay. "
United States
Derik
$87 nightly
The price is $98
Jan 2 - Jan 3, 2026
Total with taxes and fees
Nauvoo Temple House Hotel
Terrace/patio
Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison

2.5 star property
Fort Madison
9.4 out of 10, Exceptional, (645)
"Always love staying here while visiting family. Very clean and comfortable beds "
United States
Jessica
$75 nightly
The price is $84
Dec 7 - Dec 8
Total with taxes and fees
Cobblestone Inn & Suites - Fort Madison
Casino
The Catfish Bend Inn & Spa

The Catfish Bend Inn & Spa

3.5 star property
Burlington
9.2 out of 10, Wonderful, (320)
"Staff was friendly and helpful. Accomodations were excellent."
United States
Phillip
$161 nightly
The price is $180
Dec 7 - Dec 8
Total with taxes and fees
The Catfish Bend Inn & Spa
Free daily buffet breakfast
Hampton Inn Keokuk

Hampton Inn Keokuk

2.5 star property
Keokuk
8.8 out of 10, Excellent, (639)
"Very good stay. I’ll definitely stay there again "
United States
Tammy
$92 nightly
The price is $103
Jan 2 - Jan 3, 2026
Total with taxes and fees
Hampton Inn Keokuk
Exterior
Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn

2.5 star property
Mount Pleasant
8.2 out of 10, Very Good, (775)
"It was perfect. Friendly staff very clean accommodations. Sonjia Steele "
United States
Sonjia
$72 nightly
The price is $81
Dec 11 - Dec 12
Total with taxes and fees
Best Western Mt. Pleasant Inn
Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, free cribs/infant beds
Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North

2.5 star property
Keokuk
8.4 out of 10, Very Good, (748)
"Great staff! Clean hotel!"
United States
Matthew
$80 nightly
The price is $89
Jan 4 - Jan 5, 2026
Total with taxes and fees
Quality Inn & Suites Keokuk North
Double Room, 2 Double Beds | Pillowtop beds, desk, blackout drapes, iron/ironing board
Super 8 by Wyndham Mt Pleasant

Super 8 by Wyndham Mt Pleasant

2.0 star property
Mount Pleasant
8.2 out of 10, Very Good, (837)
"The room was clean and the staff was very nice and accommodating. Will definitely be staying there again in future visits to Iowa."
United States
Vicki
$65 nightly
The price is $72
Jan 4 - Jan 5, 2026
Total with taxes and fees
Super 8 by Wyndham Mt Pleasant
Reception
Quality Inn & Suites

Quality Inn & Suites

2.5 star property
Mount Pleasant
7.8 out of 10, Good, (110)
"Clean, good breakfast, great staff "
United States
Melissa
$63 nightly
The price is $71
Jan 4 - Jan 5, 2026
Total with taxes and fees
Quality Inn & Suites
Free daily buffet breakfast
Holiday Inn Express Hotel & Suites Burlington by IHG

Holiday Inn Express Hotel & Suites Burlington by IHG

2.5 star property
Burlington
8.6 out of 10, Excellent, (463)
"Friendly staff and very clean hotel"
United States
Julie
$110 nightly
The price is $123
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express Hotel & Suites Burlington by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southeast Iowa Hotel Reviews

Comfort Suites Burlington

Comfort Suites Burlington

10/10 Excellent
"It was not spotless there were"
Alicia 3-night trip
Posted 5 days ago
Comfort Suites Burlington
Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison

10/10 Excellent
"One of the nicer stays we have experienced. Great clean room and breakfast. Helpful staff."
kurt 2-night trip
Posted 7 days ago
Cobblestone Inn & Suites - Fort Madison

Frequently asked questions

How much do hotels with suites in Southeast Iowa cost?
You can expect to pay between $71 and $180 per night for hotels with suites in Southeast Iowa. Whatever your needs or budget, we'll help you find a home away from home with the extra space you need. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best hotels with suites in Southeast Iowa?
Kick back in one of the multiple hotels with suites in Southeast Iowa. With a total average guest review rating of 8.5, there's something for every budget and taste. Burlington has plenty of accommodations with suites, including Hampton Inn & Suites Burlington. It holds a 2.5-star rating and amenities such as a firepit and a swimming pool. Another traveler favorite in this city is The Catfish Bend Inn & Spa. As well as rooms with lots of space, this 3.5-star retreat comes with a waterslide and an electric car charging station.
What are the best cheap hotels with suites in Southeast Iowa?
It all depends on where in Southeast Iowa you're going to visit. If you're traveling to Burlington, Hampton Inn & Suites Burlington is a popular choice. Along with suites, this pocket-friendly escape includes pool sun loungers and a firepit. Making a stop in Mount Pleasant? AmericInn by Wyndham Mount Pleasant is an affordable choice with suite rooms in this city. A garden and a swimming pool are among the amenities at this stay. Hotels with suites start from just $71 per night, so your vacation doesn't have to hurt your hip pocket! If you're exploring Southeast Iowa on a budget, there are loads of terrific free attractions to add to your to-do list. Nauvoo State Park and Rheinberger House Museum are always popular with visitors. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels with suites in Southeast Iowa?
There are indeed, so gather the family and get busy organizing your Southeast Iowa adventure! If Burlington is on your list of places to visit, book a stay at The Catfish Bend Inn & Spa. This 3.5-star option is a popular family-friendly hotel with suites. It also features a lazy river and a waterslide. Another hot pick is Comfort Suites Burlington. Also in Burlington, it holds a 2.5-star rating and includes a nearby theme park, complimentary breakfast and suite rooms with lots of space to get comfy. Burlington has lots of family-friendly attractions when you're ready to go sightseeing. FunCity and Snake Alley will keep your crew entertained.
Why book your hotel with suites in Southeast Iowa with Expedia?
Whatever your budget or travel plans, we'll help you find your ideal hotel with suites in Southeast Iowa. Save cash and choose a property with a lower star rating, or splurge on a 5-star hotel and really get a taste of the "suite life." Use our handy search filters to narrow your results and then snag the best deal.
How can I find cheap hotels with suites in Southeast Iowa?
Finding a nicely priced hotel with suites in Southeast Iowa is a piece of cake with Expedia. Simply use the filter tool to choose the hotel star rating you prefer, then decide on your per-night budget. Choosing fewer amenities can also help you score bigger savings.
What is there to do in Southeast Iowa near my hotel with suites?
Whichever direction your travels take you in Southeast Iowa, there's plenty to explore here. Planning a stop in Nauvoo? Rheinberger House Museum is a top attraction to include in your itinerary.