Southern Arizona Vacations from $392

Book a Hotel + Flight or Car together to unlock savings

Your Southern Arizona Vacation

With a Southern Arizona vacation package, you can forget about planning stresses and just focus on experiencing what this interesting destination has on offer. Your trip to Southern Arizona wouldn't be complete without exploring some of its best cities, starting with Tucson. Some of the most popular attractions here include Tucson Mall and Pima Air and Space Museum. Yuma is another favorite with Southern Arizona travelers. Visitors to this city enjoy Lutes Casino and Yuma Territorial Prison State Historic Park. Start packing your suitcase, because your Southern Arizona vacation is just clicks away with Expedia.

The Latest Southern Arizona vacation packages

Price found within the past 48 hours. Click for updated prices.
Westgate Painted Mountain Golf Resort
Raintree at Phoenix South Mountain Preserve
Mountain Shadows Resort Scottsdale
Arizona Biltmore, LXR Hotels & Resorts
Scottsdale Plaza Resort
Don't see what you're looking for?
See all available trips from Columbus to Southern Arizona
View all trips

Where to stay in Southern Arizona

Find the best Southern Arizona areas and neighborhoods for the activities you enjoy most. Learn more about Southern Arizona

Discover the most popular places to visit in Southern Arizona

What to do in Southern Arizona

Southern Arizona Hotel Deals

3 Palms Tucson North Foothills

3 Palms Tucson North Foothills

3 out of 5
7411 N Oracle Rd, Tucson, AZ
Fully refundableReserve now, pay when you stay
$44 nightly
The price is $51 total per night from Oct 6 to Oct 7
$51 total
Oct 6 - Oct 7
Total with taxes and fees
9/10 Wonderful! (5,585 reviews)
"Great staff, amazing people that go above and beyond. Cant beat this place for the value."

Reviewed on Sep 30, 2025

3 Palms Tucson North Foothills
Hotel McCoy - Art, Coffee, Beer, Wine

Hotel McCoy - Art, Coffee, Beer, Wine

3 out of 5
720 W. Silverlake Road, Tucson, AZ
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from Oct 8 to Oct 9
$123 total
Oct 8 - Oct 9
Total with taxes and fees
9.2/10 Wonderful! (2,946 reviews)
"Clean rooms, great staff. Great water pressure and shower head. Quiet. The gym is basic, with everything you need for a quick workout."

Reviewed on Oct 2, 2025

Hotel McCoy - Art, Coffee, Beer, Wine
La Quinta Inn & Suites by Wyndham Tucson Airport

La Quinta Inn & Suites by Wyndham Tucson Airport

3 out of 5
7001 S Tucson Blvd, Tucson, AZ
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $83 total per night from Oct 27 to Oct 28
$83 total
Oct 27 - Oct 28
Total with taxes and fees
8.4/10 Very Good! (2,913 reviews)
"Wonderful people and everything was great"

Reviewed on Oct 1, 2025

La Quinta Inn & Suites by Wyndham Tucson Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southern Arizona Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Sky Harbor Intl. Airport (PHX)

More vacations you might like

Explore a world of travel with Expedia

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.