Southtown Vacations from $654

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Your Southtown Vacation

Book a vacation package to Southtown and discover everything this riverside neighborhood has to offer. Noted for its distilleries and craft breweries, culture and shopping, your next great adventure can be found right here. When it's time to get out and explore, you'll find a lot of popular attractions nearby including Alamo, Alamodome and Shops at Rivercenter. Tick off one or all during your trip to Southtown. Expedia can help turn your ideal Southtown vacation into reality, no matter your travel plans or budget.

The Latest Southtown Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Club Wyndham La Cascada

Club Wyndham La Cascada

Downtown San Antonio
$654
per person
Oct 28 - Oct 31
found 11 hours ago
Roundtrip flight included
New York (JFK) to San Antonio (SAT)
8.4/10 Very Good! (182 reviews)
Muy buen servicio todo muy limpio

Reviewed on Aug 1, 2026

Tx Home Group- San Antonio

Tx Home Group- San Antonio

Midtown
Save 100% on your flight
$1,179
per person
Oct 12 - Oct 19
found 1 day ago
Roundtrip non-stop flight included
Islip (ISP) to San Antonio (SAT)
7.8/10 Good! (10 reviews)
The St. Anthony, A Luxury Collection Hotel, San Antonio

The St. Anthony, A Luxury Collection Hotel, San Antonio

Downtown San Antonio
$693
per person
Oct 2 - Oct 5
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Antonio (SAT)
8.8/10 Excellent! (1,004 reviews)
Hotel Contessa

Hotel Contessa

Downtown San Antonio
$774
per person
Oct 11 - Oct 15
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Antonio (SAT)
9/10 Wonderful! (3,768 reviews)
Landing Apartments near UT San Antonio

Landing Apartments near UT San Antonio

La Cantera District
$670
per person
Oct 13 - Oct 18
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Antonio (SAT)
8.6/10 Excellent! (10 reviews)
This place is clean and as described. I am very happy with my stay at landing.

Reviewed on Jul 26, 2026

Where to stay in Southtown

Find the best Southtown areas and neighborhoods for the activities you enjoy most. Learn more about Southtown
A boat tour on a canal with a bridge in the background.

Downtown San Antonio

5 out of top 10 points of interest in this area

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Find hotels in Downtown San Antonio
A city skyline reflected in a calm body of water, a bridge, and a sunset sky.

Uptown

While visiting Uptown, you might make a stop by sights like Alamo Quarry Market and San Antonio Zoo and Aquarium.

Find hotels in Uptown
An old church with a bell tower and arches, surrounded by greenery and a stone structure.

Far West Side

1 out of top 10 points of interest in this area

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Find hotels in Far West Side
A cityscape with a prominent tower, a large body of water, and a sunset.

Medical Center District

While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and Cinemark San Antonio 16.

Find hotels in Medical Center District
A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

Find hotels in Northwest Side

Southtown Hotel Deals

Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

105 S Saint Marys Street San Antonio TX
Fully refundableReserve now, pay when you stay
$128 nightly
$151 total
Aug 16 - Aug 17
Total with taxes and fees
Drury Plaza Hotel San Antonio Riverwalk
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

303 Blum Street San Antonio TX
Fully refundableReserve now, pay when you stay
$88 nightly
$104 total
Sep 7 - Sep 8
Total with taxes and fees
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

150 E Houston St San Antonio TX
Fully refundableReserve now, pay when you stay
$144 nightly
$169 total
Aug 14 - Aug 15
Total with taxes and fees
Hotel Valencia Riverwalk
See all 4,641 properties in Southtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
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Beach Vacations
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Romantic Vacations
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Ski Vacations
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LGBTQ Friendly Vacations
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Adventure Vacations
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Where to go when
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Honeymoon Vacations
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Mountain Vacations
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Fishing Vacations
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Stay near popular Southtown attractions

Guenther Street Bridge

Learn about the local history of San Antonio with a stop at Guenther Street Bridge. Experience the entertainment choices and fascinating museums in this walkable area.
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Blue Star Contemporary Art Center

7.0/10 (2 reviews)
You can study the exhibits at Blue Star Contemporary Art Center, a museum with a story of its own, during your travels to San Antonio. Discover the entertainment choices in this walkable area, or seek out the local tours.
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San Antonio Art League Museum

You can browse the exhibits at San Antonio Art League Museum, a museum with a storied past, during your travels to San Antonio. Experience the fascinating museums and acclaimed theater scene in this walkable area.
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Classic Theater at Blue Star Arts Center

Enjoy a show at Classic Theater at Blue Star Arts Center, a storied theater in San Antonio. Experience the great live music and entertainment choices in this walkable area.
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Sterling Houston Theater at Jump-Start

Enjoy a performance at Sterling Houston Theater at Jump-Start, a storied theater in San Antonio. Discover the fascinating museums in this walkable area, or seek out the local tours.
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King William Park

You can take time to visit King William Park during your travels to San Antonio. Discover the entertainment choices and shops in this walkable area.
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Guenther House

6.0/10 (1 review)
You can browse the exhibits at Guenther House, a museum with a storied past, during your travels to San Antonio. Experience the acclaimed theater scene and great live music in this walkable area.
See properties

Texas Highway Patrol Hall of Fame and Museum

You can browse the exhibits at Texas Highway Patrol Hall of Fame and Museum, a museum with a story of its own, during your trip to San Antonio. Experience the entertainment choices and acclaimed theater scene in this walkable area.
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Things to do

Picture 5 for Activity San Antonio: Six Flags Fiesta Texas Admission Ticket

San Antonio: Six Flags Fiesta Texas Admission Ticket

$49
per adult
80% of travellers recommend
San Antonio: Six Flags Fiesta Texas Admission Ticket
San Antonio: Discovery Tour at Natural Bridge Caverns

San Antonio: Discovery Tour at Natural Bridge Caverns

$38
per adult
98% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
San Antonio: Botanical Garden Admission Ticket

San Antonio: Botanical Garden Admission Ticket

$18
per adult
100% of travellers recommend
San Antonio: Botanical Garden Admission Ticket
See all activities in San Antonio
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.