Find hotels near Spartanburg Science Center, Spartanburg from $73

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Compare 1,707 hotels close to Spartanburg Science Center with room rates, reviews, and availability. Most hotels are fully refundable.

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AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg

3.5 star property
0.5 mi from Spartanburg Science Center
9.4 out of 10, Exceptional, (583)
"Love the AC. My son moved to Spartanburg 3 years ago and we always stay here. Never disappointed"
United States
Stacey
$119 nightly
The price is $132
Dec 21 - Dec 22
Total with taxes and fees
AC Hotel by Marriott Spartanburg
Lobby
Spartanburg Marriott

Spartanburg Marriott

3.5 star property
0.3 mi from Spartanburg Science Center
8.6 out of 10, Excellent, (1016)
"Clean, very kind and helpful staff, we had a wonderful and comfortable stay. "
United States
Courtney
$127 nightly
The price is $141
Dec 7 - Dec 8
Total with taxes and fees
Spartanburg Marriott
Reception
Tru by Hilton Spartanburg

Tru by Hilton Spartanburg

2.5 star property
4.3 mi from Spartanburg Science Center
9.2 out of 10, Wonderful, (810)
"Great stay "
United States
Teresa
$95 nightly
The price is $106
Dec 21 - Dec 22
Total with taxes and fees
Tru by Hilton Spartanburg
Terrace/patio
Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg

3.0 star property
4 mi from Spartanburg Science Center
9.4 out of 10, Exceptional, (484)
"Great hotel! Clean, friendly staff, great bar and food at restaurant "
United States
Jessica
$115 nightly
The price is $128
Dec 14 - Dec 15
Total with taxes and fees
Hilton Garden Inn Spartanburg
Free daily buffet breakfast
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

2.5 star property
4 mi from Spartanburg Science Center
8.6 out of 10, Excellent, (979)
"Room was spotless, staff was very friendly. "
United States
Anne-Marie
$103 nightly
The price is $115
Dec 13 - Dec 14
Total with taxes and fees
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
Free daily on-the-go breakfast
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

2.5 star property
3.8 mi from Spartanburg Science Center
8.8 out of 10, Excellent, (707)
"Very nice hotel"
United States
Dave
$94 nightly
The price is $104
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Coffee shop
Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg

3.0 star property
4.1 mi from Spartanburg Science Center
9.4 out of 10, Exceptional, (431)
"The room was very nice and the staff was very professional "
United States
John T
$119 nightly
The price is $132
Dec 21 - Dec 22
Total with taxes and fees
Four Points by Sheraton Spartanburg
Property amenity
Residence Inn by Marriott Spartanburg Westgate

Residence Inn by Marriott Spartanburg Westgate

3.0 star property
4.1 mi from Spartanburg Science Center
9.4 out of 10, Exceptional, (212)
"Great hotel!"
United States
LeAnn
$125 nightly
The price is $139
Dec 21 - Dec 22
Total with taxes and fees
Residence Inn by Marriott Spartanburg Westgate
Free daily full breakfast
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

2.5 star property
3.6 mi from Spartanburg Science Center
8.2 out of 10, Very Good, (1001)
"Easy parking, parking lot had good lighting felt safe Breakfast had great choices always hot, I always like their waffles Rooms clean and spacious, bed was comfortable"
United States
Ronald
$98 nightly
The price is $109
Jan 1 - Jan 2, 2026
Total with taxes and fees
Comfort Suites At WestGate Mall
Lobby
ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

2.0 star property
3.7 mi from Spartanburg Science Center
8.2 out of 10, Very Good, (282)
"Nice hotel "
United States
Kierra
$73 nightly
The price is $81
Dec 8 - Dec 9
Total with taxes and fees
ECHO Suites Extended Stay by Wyndham Spartanburg
Lobby
Best Western Spartanburg Northwest

Best Western Spartanburg Northwest

3.0 star property
3.2 mi from Spartanburg Science Center
8.2 out of 10, Very Good, (816)
"Great place"
United States
Jamie
$84 nightly
The price is $93
Dec 22 - Dec 23
Total with taxes and fees
Best Western Spartanburg Northwest
Free daily buffet breakfast
Best Western Plus Spartanburg

Best Western Plus Spartanburg

2.5 star property
4.3 mi from Spartanburg Science Center
8.4 out of 10, Very Good, (1001)
"Food was great! Rooms was good!"
United States
Audrey
$84 nightly
The price is $94
Dec 14 - Dec 15
Total with taxes and fees
Best Western Plus Spartanburg
Restaurant
Holiday Inn Spartanburg Northwest by IHG

Holiday Inn Spartanburg Northwest by IHG

2.5 star property
3.2 mi from Spartanburg Science Center
7.6 out of 10, Good, (832)
"Breakfast was not free but our stay was enjoyable overall. Clean and convenient location for my work trip and staff was really friendly "
United States
Jennifer
$85 nightly
The price is $94
Dec 26 - Dec 27
Total with taxes and fees
Holiday Inn Spartanburg Northwest by IHG
Exterior
Comfort Inn & Suites Spartanburg North

Comfort Inn & Suites Spartanburg North

2.5 star property
4.5 mi from Spartanburg Science Center
7.8 out of 10, Good, (950)
"Yes, all the above very good service, thanks for making our stay comfortable. "
United States
Maxine
$89 nightly
The price is $99
Dec 7 - Dec 8
Total with taxes and fees
Comfort Inn & Suites Spartanburg North
Free daily buffet breakfast
Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85

2.5 star property
5.1 mi from Spartanburg Science Center
8.8 out of 10, Excellent, (1000)
"Convenient location, nice coffee station in lobby, good breakfast, room was average, good enough for one night stopover as I needed "
United States
John M
$78 nightly
The price is $87
Dec 21 - Dec 22
Total with taxes and fees
Hampton Inn Spartanburg-North I-85
Free buffet breakfast
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

2.5 star property
5.1 mi from Spartanburg Science Center
8.6 out of 10, Excellent, (861)
"The stay was great overall, room was exceptional in size and comfort. The noise from the highway was the only distraction but mainly because we do not ever have any. The staff was friendly and helpful. We would not hesitate to stay here again."
United States
Charmaine
$97 nightly
The price is $108
Dec 21 - Dec 22
Total with taxes and fees
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Exterior
USA Economy Lodge

USA Economy Lodge

2.0 star property
3.4 mi from Spartanburg Science Center
7.6 out of 10, Good, (79)
"Loved it very quiet and pleasant "
United States
Tameesha
$72 nightly
The price is $80
Dec 15 - Dec 16
Total with taxes and fees
USA Economy Lodge
Property amenity
Residence Inn by Marriott Spartanburg

Residence Inn by Marriott Spartanburg

3.0 star property
4.1 mi from Spartanburg Science Center
8.0 out of 10, Very Good, (461)
"Nell and Donna made the best breakfast! They were so sweet and were constantly working! P"
United States
Karri
$103 nightly
The price is $115
Dec 11 - Dec 12
Total with taxes and fees
Residence Inn by Marriott Spartanburg
Exterior
Red Roof Inn Spartanburg - I-85

Red Roof Inn Spartanburg - I-85

2.0 star property
4.8 mi from Spartanburg Science Center
6.6 out of 10, (233)
"Simple easy check in , "
United States
Meghan
$66 nightly
The price is $73
Dec 6 - Dec 7
Total with taxes and fees
Red Roof Inn Spartanburg - I-85
Desk, laptop workspace, blackout drapes, free WiFi
Motel 6 Spartanburg, Sc – Northwest / Business 85

Motel 6 Spartanburg, Sc – Northwest / Business 85

2.0 star property
3.2 mi from Spartanburg Science Center
7.2 out of 10, Good, (71)
"It’s a quiet laid back hotel with clean rooms!"
United States
Terrence
$77 nightly
The price is $85
Dec 5 - Dec 6
Total with taxes and fees
Motel 6 Spartanburg, Sc – Northwest / Business 85
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Spartanburg Science Center Hotel Reviews

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

10/10 Excellent
"Clean room friendly staff "
pamela 1-night trip
Posted 3 days ago
Comfort Inn & Suites Greer - Greenville

Hotels near other Spartanburg Science Center attractions

Spartanburg Regional History Museum

You can spend time browsing the exhibits at Spartanburg Regional History Museum during your travels in Spartanburg. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Chapman Cultural Center

4.7/5 (3 reviews)
You can enjoy a show at Chapman Cultural Center during your trip to Spartanburg. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Spartanburg Science Center?
Spartanburg Science Center is located in Spartanburg. This family-friendly area is known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 28 hotels and other accommodations you'll find within a mile.
Where is the best place to stay near Spartanburg Science Center?
Adjacent to Spartanburg Science Center, Spartanburg Marriott is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and free parking. Other good choices within 5 miles include ECHO Suites Extended Stay by Wyndham Spartanburg and Comfort Suites At WestGate Mall.
How many hotels are there close to Spartanburg Science Center?
Expedia has 28 hotels and other accommodations within a mile from Spartanburg Science Center.
If I need to cancel the hotel reservation for my stay near Spartanburg Science Center, will I receive a refund?
Yes! The majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view top deals close to Spartanburg Science Center.
Where can I learn more about changing or cancelling my trip in the area near Spartanburg Science Center?
For more information about picking new dates or cancelling your stay near Spartanburg Science Center, click here.
What can I see and do near Spartanburg Science Center?
You'll want to browse the exhibits at Hub City Railroad Museum and Spartanburg Regional History Museum. Learn about local history at Spartanburg Memorial Auditorium and Spartanburg Regional Hospital. You can check out the local talent at Chapman Cultural Center, Twitchell Auditorium, and Rainey Amphitheater.