A forested landscape with a winding road and distant hills under a partly cloudy sky.

Spessart-Main-Odenwald Vacations from $1,891

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Your Spessart-Main-Odenwald Vacation

Reserve a Spessart-Main-Odenwald vacation package and wander wherever your adventurous soul takes you. This destination has so much to offer, including its views, markets, festivals, and much more. Start your trip to Spessart-Main-Odenwald with a few nights in Frankfurt visiting popular attractions like Deutsche Bank Park and Frankfurt Christmas Market. Aschaffenburg is another city that lures travelers from far and wide. Mespelbrunn Castle and Schoenbusch Park are two of the top places to see here. If you're ready to stop dreaming and start traveling, Expedia will help turn your Spessart-Main-Odenwald vacation into a reality.

The Latest Spessart-Main-Odenwald Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • A modern kitchen with a black marble backsplash, a built-in stove, and a wooden countertop.
    Jan 27 - Feb 2

    Hotel Attaché by ANS + Flight

    Gallus
    5 nights
    3.0 star property
    8.0/10 - Very good (647 reviews)
    "This guy assist me is not good asking me the money"
    Reviewed September 25, 2026
    Roundtrip • Phoenix (PHX) - Frankfurt (FRA)
    PHX - FRA • 1 stop FRA - PHX • 1 stop
    $2,478
    $1,891
    per traveler
    found 1 day ago
    Hotel Attaché by ANS
  • A breakfast buffet with various food items, drinks, and a view of greenery outside.
    Jan 27 - Feb 2

    Villa Westend Hotel an der Messe + Flight

    Westend-Süd
    5 nights
    4.0 star property
    8.2/10 - Very good (205 reviews)
    "I was very happy to find this boutique hotel within shouting distance of the Messe. For many years I stayed at the Marriott but wanted a change. It is a charming, quiet and comfortable hotel. The staff are particularly good natured and helpful. I hope no one reads this review so the rates don’t go up too much for next year. Be aware though it’s not fancy or upscale so if that is what you are after it may not be the right fit for you."
    Reviewed October 9, 2026
    Roundtrip • Phoenix (PHX) - Frankfurt (FRA)
    PHX - FRA • 1 stop FRA - PHX • 1 stop
    Save 100% on your flight
    $3,272
    $2,294
    per traveler
    found 1 day ago
    Villa Westend Hotel an der Messe
  • A modern high-rise building with a cylindrical glass tower, surrounded by other contemporary buildings.
    Dec 19 - Dec 25

    Holiday Inn Frankfurt - Alte Oper by IHG + Flight

    Bahnhofsviertel
    5 nights
    4.0 star property
    8.8/10 - Excellent (885 reviews)
    Roundtrip • Dallas (DFW) - Frankfurt (FRA)
    DFW - FRA • Nonstop FRA - DFW • Nonstop
    $2,703
    $2,180
    per traveler
    found 1 day ago
    Holiday Inn Frankfurt - Alte Oper by IHG
  • A modern hotel room with a large bed, a sofa, a small table, and a view of the cityscape through large windows.
    Jan 26 - Feb 2

    NH Collection Frankfurt Spin Tower + Flight

    Gallus
    6 nights
    4.5 star property
    9.0/10 - Wonderful (788 reviews)
    "Nice spot"
    Reviewed November 10, 2026
    Roundtrip • Phoenix (PHX) - Frankfurt (FRA)
    PHX - FRA • 1 stop FRA - PHX • 1 stop
    $8,751
    $7,095
    per traveler
    found 1 day ago
    NH Collection Frankfurt Spin Tower
  • A modern restaurant with wooden tables and chairs, a digital menu display, and large windows offering a view of the outside.
    Jan 26 - Feb 2

    Holiday Inn Express Darmstadt by IHG + Flight

    Darmstadt
    6 nights
    3.5 star property
    9.0/10 - Wonderful (346 reviews)
    "Climate control was not able to maintain a comfortable temperature in the room"
    Reviewed November 2, 2026
    Roundtrip • Phoenix (PHX) - Frankfurt (FRA)
    PHX - FRA • 1 stop FRA - PHX • 1 stop
    $7,308
    $5,936
    per traveler
    found 1 day ago
    Holiday Inn Express Darmstadt by IHG

Discover the most popular places to visit in Spessart-Main-Odenwald

A Christmas market with illuminated stalls and a large decorated tree.

Frankfurt Christmas Market

9.0/10 (579 reviews)
You can find the perfect gifts to bring home at Frankfurt Christmas Market during your stay in Frankfurt. Experience the fascinating museums or attend a sporting event in this walkable area.
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Spessart-Main-Odenwald Hotel Deals

A modern lobby with a leather sofa, a yellow chair, a small table, and a large potted plant.

B&B HOTEL Aschaffenburg-City

B&B HOTEL Aschaffenburg-City
10.2 mi from Spessart-Main-Odenwald
9.0 out of 10, Wonderful, (272 reviews)
$84 nightly
The price is $90
Dec 7 - Dec 8
Total with taxes and fees
B&B HOTEL Aschaffenburg-City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.