
St. Charles Vacations from $490
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Your St. Charles Vacation
When you book a St. Charles vacation package, it's easy to enjoy your getaway to the fullest. Uncover the highlights of this vibrant city knowing that all the travel planning has been organized in advance. Any trip to St. Charles has to include a little sightseeing. Whitewater State Park is a good place to start your exploring. Whoever you're escaping with and whatever you want to spend, your dream St. Charles vacation is just a few clicks away with Expedia.
The Latest St. Charles vacation packages
Price found within the past 48 hours. Click for updated prices.

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Downtown Rochester
per person
Nov 1 - Nov 6
found 17 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
8.8/10 Excellent! (801 reviews)
Great place, staff was friendly. Beds were comfortable. Would stay again.
Reviewed on Aug 17, 2025

Comfort Inn & Suites West - Medical Center
per person
Nov 1 - Nov 6
found 17 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
9/10 Wonderful! (477 reviews)
Stayed just overnght to meet family. Very comfortable stay with everything we needed. I did wish they had some streaming options, however.
Reviewed on Aug 12, 2025

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Kutzky Park
per person
Nov 1 - Nov 6
found 17 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
9.2/10 Wonderful! (439 reviews)
I did'nt like the parking very tight spaces.
My room was nice and clean later at night our AC started leaking water. They would fix next day but the dripping was too noisy and had to get moved to another room.
Reviewed on Aug 16, 2025

Aspen Select
per person
Nov 1 - Nov 6
found 17 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
8.4/10 Very Good! (1,001 reviews)
Very affordable
The property seems a bit run down and breakfast was not great.
The staff was really nice and helpful.
The rooms were well maintained.
Reviewed on Aug 16, 2025

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View all tripsSt. Charles Hotel Deals

White Valley Motel
449 W. 6th Street, St. Charles, MN
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $77 total per night from Aug 19 to Aug 20
$77 total
Aug 19 - Aug 20
Total includes taxes and fees
5.8/10 (113 reviews)
"Place is clean but old. Staff got great personality and nice"
Reviewed on Jun 22, 2025

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $140 total per night from Aug 21 to Aug 22
$140 total
Aug 21 - Aug 22
Total includes taxes and fees
8.2/10 Very Good! (1,523 reviews)
Great stay but complicated arrival by car
"Both staffing arrival and Mayo Clinic construction will continue to be a challenge for guests at the Kahler Grand for a few months. Hopefully more bell/valet staff can be added and arrival moved back to proper entrance. Until then arrival by car for registration can be chaotic/-once insid at the ..."
Reviewed on Aug 17, 2025

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $119 total per night from Aug 29 to Aug 30
$119 total
Aug 29 - Aug 30
Total includes taxes and fees
9/10 Wonderful! (996 reviews)
"Room smelled exceptionally clean upon opening the door! Nothing in the room was dated or worn. We haven’t seen that lately in other stays!"
Reviewed on Aug 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.