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St. Charles Vacation Travel Guide

Vacationing is good for the soul. It lets you rest, relax, recharge, and refresh, so you’re ready to take on new endeavors when you return home. When it’s time to let loose and embark on a group adventure or unwind and rejuvenate on a solo sojourn, turn to Expedia for major discounts on St. Charles vacation packages.

It’s easy to book the getaway of your dreams when you search through our selection of St. Charles vacations. Our goal? To create the perfect trip for you by providing the largest selection of vacation packages. Confidently book your getaway thanks to our trustworthy recommendations and verified consumer reviews from travelers just like you. Personalize your St. Charles package with our myriad of hotel rooms and flight tickets, which help to create a vacation specifically for you. Simply sort through our selection and pick and choose the elements that best suit your preferences and price range.

Because we offer the best rates, you can book your travel reservations knowing you won’t find lower prices elsewhere. These discounts are so great, you’ll feel like you gained the title of the ultimate bargain hunter with our St. Charles vacation package deals. Whether you’re looking to book multiple flights, stay at the fanciest hotel, or explore the hottest local attractions, you’ll find discounted travel arrangements within your budget right here. You shouldn’t have a care in the world when you go on vacation, so our discounts allow you to rest easy without giving your bank account a second thought. Save money on your vacation today and revel in your much-deserved getaway tomorrow.


Top Hotel Deals

See all 97 Hotels in St. Charles
White Valley Motel $60
White Valley Motel

White Valley Motel

449 W. 6th Street, St. Charles
     
    3.0
    of 5, from 24 reviews
    2.5 out of 5.0

    Situated in St. Charles, this motel is in the same region as Whitewater State Park and Carley State Park.

    Kahler Inn and Suites - Mayo Clinic Area $69
    Kahler Inn and Suites - Mayo Clinic Area

    Kahler Inn and Suites - Mayo Clinic Area

    9 3rd Ave Nw, Rochester
       
      3.8
      of 5, from 1,148 reviews
      3.5 out of 5.0

      Experience the look and feel of the Kahler Inn & Suites. Every room has refrigerators, flat screen televisions, coffee makers, furniture, and more!

      Kahler Apache $76
      Kahler Apache

      Kahler Apache

      1517 16th St Sw, Rochester
         
        3.5
        of 5, from 732 reviews
        3.0 out of 5.0

        This family-friendly Rochester hotel is located in a shopping district, within 2 mi (3 km) of Apache Mall and Plummer House. Mayo Clinic is 2.2 mi (3.6 km) away.

        Kahler Grand Hotel $89
        Kahler Grand Hotel

        Kahler Grand Hotel

        20 2nd Ave Sw, Rochester
           
          3.4
          of 5, from 1,947 reviews
          3.0 out of 5.0

          Located in the heart of Rochester, this hotel is within 1 mi (2 km) of University of Minnesota-Rochester and Mayo Clinic. Shops University Square and Rochester Civic Theater are also within 10 minutes.

          Country Inn & Suites by Radisson, Rochester South, MN $89
          Country Inn & Suites by Radisson, Rochester South, MN

          Country Inn & Suites by Radisson, Rochester South, MN

          77 Woodlake Drive SE, Rochester
             
            4.2
            of 5, from 509 reviews
            3.0 out of 5.0

            Situated near the airport, this hotel is within 6 mi (10 km) of Olmsted County Fairgrounds, Soldiers Field Veterans Memorial, and Mayo Civic Center. Mayo Clinic and Apache Mall are also within 6 mi (10 km).

            Days Inn by Wyndham Rochester Downtown $61
            Days Inn by Wyndham Rochester Downtown

            Days Inn by Wyndham Rochester Downtown

            6 1st Avenue Northwest, Rochester
               
              2.8
              of 5, from 707 reviews
              2.0 out of 5.0

              Situated in Rochester, this hotel is steps from University of Minnesota-Rochester and Mayo Clinic. Shops University Square and Rochester Civic Theater are also within 10 minutes.

              GuestHouse International Inn & Suites Rochester $76
              GuestHouse International Inn & Suites Rochester

              GuestHouse International Inn & Suites Rochester

              435 16th Ave Nw, Rochester
                 
                3.7
                of 5, from 974 reviews
                2.5 out of 5.0

                Situated in Rochester, this motel is 0.6 mi (1 km) from Saint Marys Hospital and 1.3 mi (2.1 km) from Mayo Clinic. Assisi Heights and Plummer House are also within 2 mi (3 km).

                Super 8 by Wyndham Rochester Mayo Clinic Area $60
                Super 8 by Wyndham Rochester Mayo Clinic Area

                Super 8 by Wyndham Rochester Mayo Clinic Area

                106 SE 21st Street, Rochester
                   
                  3.7
                  of 5, from 429 reviews
                  2.0 out of 5.0

                  Situated in Rochester, this hotel is 0.9 mi (1.4 km) from Olmsted County Fairgrounds and 2.3 mi (3.8 km) from Mayo Clinic. Soldiers Field Golf Course and Apache Mall are also within 2 mi (3 km).

                  Top Deals on Flights

                  These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.