St. Charles Vacations from $490

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Your St. Charles Vacation

When you book a St. Charles vacation package, it's easy to enjoy your getaway to the fullest. Uncover the highlights of this vibrant city knowing that all the travel planning has been organized in advance. Any trip to St. Charles has to include a little sightseeing. Whitewater State Park is a good place to start your exploring. Whoever you're escaping with and whatever you want to spend, your dream St. Charles vacation is just a few clicks away with Expedia.

The Latest St. Charles vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
Downtown Rochester
per person
Nov 1 - Nov 6
found 17 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
8.8/10 Excellent! (801 reviews)
Great place, staff was friendly. Beds were comfortable. Would stay again.

Reviewed on Aug 17, 2025

Comfort Inn & Suites West - Medical Center

Comfort Inn & Suites West - Medical Center

3 out of 5
per person
Nov 1 - Nov 6
found 17 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
9/10 Wonderful! (477 reviews)
Stayed just overnght to meet family. Very comfortable stay with everything we needed. I did wish they had some streaming options, however.

Reviewed on Aug 12, 2025

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

3 out of 5
Kutzky Park
per person
Nov 1 - Nov 6
found 17 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
9.2/10 Wonderful! (439 reviews)
I did'nt like the parking very tight spaces. My room was nice and clean later at night our AC started leaking water. They would fix next day but the dripping was too noisy and had to get moved to another room.

Reviewed on Aug 16, 2025

Aspen Select

Aspen Select

3.5 out of 5
per person
Nov 1 - Nov 6
found 17 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
8.4/10 Very Good! (1,001 reviews)
Very affordable The property seems a bit run down and breakfast was not great. The staff was really nice and helpful. The rooms were well maintained.

Reviewed on Aug 16, 2025

Days Inn by Wyndham Austin

Days Inn by Wyndham Austin

2 out of 5
per person
Nov 1 - Nov 6
found 17 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Rochester (RST)
8/10 Very Good! (670 reviews)
Friendly staff, clean hotel.

Reviewed on Aug 10, 2025

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St. Charles Hotel Deals

White Valley Motel

White Valley Motel

2.5 out of 5
449 W. 6th Street, St. Charles, MN
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $77 total per night from Aug 19 to Aug 20
$77 total
Aug 19 - Aug 20
Total includes taxes and fees
5.8/10 (113 reviews)
"Place is clean but old. Staff got great personality and nice"

Reviewed on Jun 22, 2025

White Valley Motel
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $140 total per night from Aug 21 to Aug 22
$140 total
Aug 21 - Aug 22
Total includes taxes and fees
8.2/10 Very Good! (1,523 reviews)
Great stay but complicated arrival by car
"Both staffing arrival and Mayo Clinic construction will continue to be a challenge for guests at the Kahler Grand for a few months. Hopefully more bell/valet staff can be added and arrival moved back to proper entrance. Until then arrival by car for registration can be chaotic/-once insid at the ..."

Reviewed on Aug 17, 2025

Kahler Grand Hotel
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $119 total per night from Aug 29 to Aug 30
$119 total
Aug 29 - Aug 30
Total includes taxes and fees
9/10 Wonderful! (996 reviews)
"Room smelled exceptionally clean upon opening the door! Nothing in the room was dated or worn. We haven’t seen that lately in other stays!"

Reviewed on Aug 17, 2025

Hyatt House Rochester/Mayo Clinic Area
See all 488 properties in St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a St. Charles vacation package cost?
You can grab a vacation package to this destination from $490 on Expedia. But how much your vacation to St. Charles costs will depend on factors like the season, length of stay and hotel choice.
What are the cheapest months to go to St. Charles?
January, February and November are great times to search for cheap St. Charles vacation packages. Traveling in less busy months means you can usually find reduced prices on hotels and flights.
How many days is enough for St. Charles?
Generally, a handful of days is enough to check out the main attractions during your St. Charles vacation. However, if you want to have more time to relax or go on day tours, consider extending your itinerary.
How to find the best St. Charles package deals?
Use Expedia's filter tool to find some terrific St. Charles package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or browse for St. Charles package deals in the low season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to book your vacation package as soon as possible.
Is it cheaper to book a St. Charles vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking hotels and flights separately. Better still, you can customize your St. Charles escape to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to St. Charles?
If you've got your St. Charles travel dates finalized, book early to grab some outstanding deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spontaneous adventures? Our last-minute deals are ideal for setting off on a whim.
Does Expedia offer Book Now, Pay Later St. Charles vacation packages?
Your St. Charles getaway should be a relaxing escape from your busy life, not a reason for money-related stress. So to allow you a little more flexibility, we've partnered with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.