An aerial view of a town with industrial buildings, roads, and green areas.

St. Charles Vacation Rentals

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Check prices for these dates

In two weeks
Oct 16 - Oct 18
In two months
Nov 27 - Nov 29
In three months
Dec 25 - Dec 27
In four months
Jan 22 - Jan 24

Our top choices for St. Charles vacation rentals

A wooden cabin with a porch, two chairs, and a door.

1. Tiny Treehouse Cabin | Bluff Woodlands #2

Tiny Treehouse Cabin | Bluff Woodlands #2
Elba
9.8 out of 10, Exceptional, (17 reviews)
"Beautiful area enjoyed our stay immensely"
United Kingdom
I.M l.
$178 nightly
The price is $191
Sep 29 - Sep 30
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #2
A covered deck with outdoor seating, surrounded by a forested area.

2. Tiny Treehouse Cabin | Bluff Woodlands #3

Tiny Treehouse Cabin | Bluff Woodlands #3
Elba
10.0 out of 10, Exceptional, (13 reviews)
"My family of 4 had a wonderful stay!"
United States
Josh S.
$189 nightly
The price is $203
Sep 29 - Sep 30
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #3
A wooden cabin with a porch, two chairs, and a door.

3. Three Treehouse Cabins in the Bluff Woodlands

Three Treehouse Cabins in the Bluff Woodlands
Elba
$497 nightly
The price is $535
Sep 29 - Sep 30
Total with taxes and fees
Three Treehouse Cabins in the Bluff Woodlands
A two-story house with a covered patio and a pathway leading to the entrance.

4. Magical Nest Hideaway

Magical Nest Hideaway
Rochester
10.0 out of 10, Exceptional, (166 reviews)
"An excellent place to stay! Clean, private, safe and beautiful neighborhood. "
United States
Brandi B.
$150 nightly
The price is $173
Oct 2 - Oct 3
Total with taxes and fees
Magical Nest Hideaway
A backyard with a picnic table, string lights, and a wooden fence.

5. Rose’s Barnhouse Loft | Cozy Farm-Inspired Stay

Rose’s Barnhouse Loft | Cozy Farm-Inspired Stay
East Side Pioneers
$122 nightly
The price is $125
Oct 2 - Oct 3
Total with taxes and fees
Rose’s Barnhouse Loft | Cozy Farm-Inspired Stay
A dining room with a white table, white chairs, a chandelier, and a potted plant.

6. Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
East Side Pioneers
9.4 out of 10, Exceptional, (22 reviews)
"The place was great"
United States
Michelle L.
$171 nightly
The price is $197
Oct 6 - Oct 7
Total with taxes and fees
Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

7. The Berkman

The Berkman
3.0 star property
Folwell
9.6 out of 10, Exceptional, (444 reviews)
"Excellent service and wonderful room!"
United States
Suzette
$178 nightly
The price is $205
Sep 29 - Sep 30
Total with taxes and fees
The Berkman
A living room with a dark brown sofa, two trash bins, a framed artwork of an artichoke, and a lamp on a side table.

8. Across from St Marys hospital Covered By Faith 2

Across from St Marys hospital Covered By Faith 2
Kutzky Park
8.0 out of 10, Very good, (2 reviews)
"Easy check in/ Secure entry system "
United States
Ann R.
$140 nightly
The price is $161
Sep 29 - Sep 30
Total with taxes and fees
Across from St Marys hospital Covered By Faith 2
Two wooden cabins elevated on stilts in a forest, with outdoor seating and hammocks.

9. Tiny Treehouse Cabin | Bluff Woodlands #1

Tiny Treehouse Cabin | Bluff Woodlands #1
Elba
9.6 out of 10, Exceptional, (10 reviews)
"Great area a place to stay. "
United States
Paul T.
$189 nightly
The price is $203
Sep 29 - Sep 30
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #1
A row of stacked front-loading washing machines in a laundry room with a tiled floor.

10. Suite w/ Kitchen + Breakfast | Near Mayo Clinic

Suite w/ Kitchen + Breakfast | Near Mayo Clinic
Rochester
$176 nightly
The price is $202
Oct 8 - Oct 9
Total with taxes and fees
Suite w/ Kitchen + Breakfast | Near Mayo Clinic
A small brick building with a sign reading 'WYKOFF JAIL HOUSE.'

11. Wykoff Historical Jail Haus with Original Jail Cell Bunks.

Wykoff Historical Jail Haus with Original Jail Cell Bunks.
Wykoff
10.0 out of 10, Exceptional, (5 reviews)
"Phenomenal communication with Becky, our host. Will be coming to this property again. It is unique and unlike anything I ever stayed at before. It was a jail in its former life after all. Very authentic with a modern twist. Great place!!!"
United States
Peggy
$115 nightly
The price is $123
Oct 5 - Oct 6
Total with taxes and fees
Wykoff Historical Jail Haus with Original Jail Cell Bunks.
A living room with a television displaying a scenic view, a dark armchair, a sofa, and a wooden coffee table.

12. 2 steps entry 1mile to Mayo CoveredByFaith Inspire

2 steps entry 1mile to Mayo CoveredByFaith Inspire
Parkway
10.0 out of 10, Exceptional, (3 reviews)
"Great pet friendly option"
United States
Erik G.
$230 nightly
The price is $265
Oct 1 - Oct 2
Total with taxes and fees
2 steps entry 1mile to Mayo CoveredByFaith Inspire
A kitchen with white cabinets, a sink, and a coffee maker.

13. Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!

Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!
Rochester
9.4 out of 10, Exceptional, (33 reviews)
"This was a very clean and cozy property."
United States
Angela O.
$191 nightly
The price is $220
Oct 25 - Oct 26
Total with taxes and fees
Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!
A compact living space with a dining area, kitchenette, and a seating area with a sofa and chairs.

14. Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!

Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!
Rochester
10.0 out of 10, Exceptional, (11 reviews)
"It was amazing stay, it was very comfy, welcoming and definitely something we would book again!!"
United States
Jessica Z.
$218 nightly
The price is $251
Sep 29 - Sep 30
Total with taxes and fees
Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!
A modern living room with a brown leather sofa, a white armchair, a coffee table, and a dining area with a table and chairs.

15. The June | Private 1br Basement Apt, Pets Welcome!

The June | Private 1br Basement Apt, Pets Welcome!
Rochester
10.0 out of 10, Exceptional, (7 reviews)
"This place was quiet, comfortable, well-stocked, and incredibly close to everything we were looking for. The hosts were great communicators, and accessing the place was a snap."
United States
Josh P.
$185 nightly
The price is $213
Oct 4 - Oct 5
Total with taxes and fees
The June | Private 1br Basement Apt, Pets Welcome!
A living room with a flat-screen TV on a wooden stand, a gray sofa, and a blue armchair.

16. Close to Mayo/Shops, 1 step entry Covered By Faith

Close to Mayo/Shops, 1 step entry Covered By Faith
Rochester
9.8 out of 10, Exceptional, (13 reviews)
"The host was so incredibly responsive whenever we had questions, the house was incredibly clean and welcoming, and we enjoyed our stay there."
United States
Anonymous traveler
$252 nightly
The price is $290
Sep 29 - Sep 30
Total with taxes and fees
Close to Mayo/Shops, 1 step entry Covered By Faith
A living room with a television, sofa, coffee table, and shelves with decorative items.

17. Vintage Lustron Home Piece of History

Vintage Lustron Home Piece of History
Minnesota City
10.0 out of 10, Exceptional, (36 reviews)
"A beautiful comfortable welcoming home!"
United States
Jocelyn R.
$195 nightly
The price is $210
Sep 29 - Sep 30
Total with taxes and fees
Vintage Lustron Home Piece of History
A residential building with a dark blue front door, a small porch with a metal railing, and a brick facade.

18. Across from St Marys hospital Covered By Faith 1

Across from St Marys hospital Covered By Faith 1
Kutzky Park
4.0 out of 10, (1 review)
$140 nightly
The price is $161
Sep 30 - Oct 1
Total with taxes and fees
Across from St Marys hospital Covered By Faith 1
A modern apartment with a staircase, a dining area, and a living space.

19. Charming 3-bedroom, 2 bathroom house with outdoor space in Winona

Charming 3-bedroom, 2 bathroom house with outdoor space in Winona
Winona
10.0 out of 10, Exceptional, (34 reviews)
"A charming place to stay with a spacious primary bedroom, laundry room, and living areas. The backyard patio is a perfect place for a morning coffee and a quiet evening. We would definitely rebook on our next visit."
United States
Mainul
$254 nightly
The price is $273
Sep 29 - Sep 30
Total with taxes and fees
Charming 3-bedroom, 2 bathroom house with outdoor space in Winona
A compact RV kitchen with wooden cabinets, a stove, and a dining area with a bench.

20. Big River Escape Coyote Camper #1

Big River Escape Coyote Camper #1
Buffalo City
10.0 out of 10, Exceptional, (2 reviews)
"Awesome as usual "
United States
Matthew B.
$138 nightly
The price is $146
Sep 29 - Sep 30
Total with taxes and fees
Big River Escape Coyote Camper #1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Hampton Inn Rochester-South

Hampton Inn Rochester-South

10/10 Excellent
"Very comfortable stay with friendly accommodating staff and service to our room. Breakfast was very nice with much variety and even gluten free choices which I needed. There is a daily soup offered in the evening, all of which made for a pleasant stay. I would definitely stay there again."
JKathleen 3-night trip
Posted 1 hour ago
Hampton Inn Rochester-South

Find out more about St. Charles

Everything you need to know about St. Charles vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Charles vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Charles in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $173 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Charles rentals

At Expedia, we put the best St. Charles vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, we offer vacation rentals close to the most popular attractions in St. Charles, or you can go with a more remote option if you want a relaxing place to stay. St. Charles is known for its parks.

What are some of the best vacation rentals that St. Charles has to offer?

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom: Visitors like this St. Charles vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind.

What can I see and do in St. Charles?

While you're exploring the area, Whitewater River and Quarry Hill Nature Center are a couple of picturesque spots to get outside and enjoy nature. Whitewater State Park and St. Mary's University of Minnesota are a couple of places you'll find in the larger area.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned properties you can book for short or long periods in St. Charles. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so your stay will be comfortable. If you're concerned about a clean environment, a vacation rental can offer a sense of seclusion away from public hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for families.