St. John Vacations from $252

Book a Hotel + Flight or Car together to unlock savings

Plan, book, travel with confidence
Better together
Save up to $2,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Your St. John Vacation

From its highlights to its hidden gems, this city is best explored with a St. John vacation package. Check out hotels located in Downtown St. Louis, which is great for festivals, bars and pubs and dining. Make your trip to St. John even more enjoyable by going sightseeing. St. Louis Zoo, St. Louis Art Museum and Washington University in St. Louis are some of the most popular attractions you'll want to explore. Whatever your travel plans or budget, organizing a tailored St. John vacation is a cinch with Expedia.

The Latest St. John Vacation Packages

Price found within the past 48 hours. Click for updated prices.

The Wildwood Hotel

$252

per person

Oct 13 - Oct 16

found 1 day ago

Roundtrip flight included

Denver (DEN) to St. Louis (STL)

9.2/10 Wonderful! (1,672 reviews)

This place is great and so are the staff. I would not expect a place this nice to allow pets.

Reviewed on Aug 8, 2026

Remodeled and Inviting Free EV

Save 100% on your flight

$551

per person

Sep 27 - Oct 2

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

10/10 Exceptional! (1 review)

It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it

Reviewed on Aug 7, 2026

Residence Inn by Marriott St Louis Downtown

Midtown

Save 100% on your flight

$349

per person

Sep 24 - Sep 28

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

7.8/10 Good! (1,002 reviews)

1) Put a number of towels based on the amounth of people in the room. 2) Insert something to put clothes during shower.

Reviewed on Aug 6, 2026

The Cheshire

Save 100% on your flight

$510

per person

Sep 12 - Sep 17

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

8.8/10 Excellent! (1,005 reviews)

Bosso was an excellent meal with good ambience and well worth the price.

Reviewed on Aug 7, 2026

Moonrise Hotel

Delmar Loop

Save 100% on your flight

$473

per person

Sep 24 - Sep 28

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

9/10 Wonderful! (2,006 reviews)

Where to stay in St. John

Find the best St. John areas and neighborhoods for the activities you enjoy most. Learn more about St. John

A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis

3 out of top 10 points of interest in this area

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

An ornate hall with arched ceilings and intricate patterns.

Downtown West

3 out of top 10 points of interest in this area

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

A street with parked cars, a building with a sign reading "Brennan's", and a tree in front.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

St. John Hotel Deals

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO

Fully refundableReserve now, pay when you stay

$134 nightly

$158 total

Aug 28 - Aug 29

Total with taxes and fees

8.6/10 Excellent! (4,191 reviews)

"Love this place will difinitely stay there again"

Reviewed on Aug 7, 2026

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO

Fully refundableReserve now, pay when you stay

$91 nightly

$106 total

Aug 30 - Aug 31

Total with taxes and fees

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive Maryland Heights MO

Fully refundableReserve now, pay when you stay

$125 nightly

$146 total

Aug 16 - Aug 17

Total with taxes and fees

8.6/10 Excellent! (2,202 reviews)

"Room was clean and comfortable. Did not care for the pillows, they were hard. Mini fridge in room but no microwave."

Reviewed on Aug 7, 2026

See all 2,006 properties in St. John

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.