St. John Vacations from $496

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Your St. John Vacation

From its highlights to its hidden gems, this city is best explored with a St. John vacation package. Check out hotels located in Downtown St. Louis, which is great for festivals, bars and pubs and dining. Make your trip to St. John even more enjoyable by going sightseeing. St. Louis Zoo, St. Louis Art Museum and Washington University in St. Louis are some of the most popular attractions you'll want to explore. Whatever your travel plans or budget, organizing a tailored St. John vacation is a cinch with Expedia.

The Latest St. John Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Knight Center at Washington University

The Knight Center at Washington University

2.5 out of 5
Price was $637, price is now $496 per person
$496
per person
May 28 - May 31
found 20 hours ago
Roundtrip flight included
New York (NYC) to St. Louis (STL)
9.4/10 Exceptional! (496 reviews)
Great place to stay on campus. Extremely helpful and friendly staff you don’t typically find at the chain hotels.

Reviewed on Mar 14, 2026

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $1,841, price is now $1,116 per person
$1,116
per person
Apr 22 - Apr 26
found 1 day ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
9.2/10 Wonderful! (1,620 reviews)
the hotel is very comfortable and the staff was very helpful.

Reviewed on Mar 20, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
Grand Center
Price was $821, price is now $623 per person
$623
per person
May 28 - May 31
found 20 hours ago
Roundtrip flight included
New York (NYC) to St. Louis (STL)
8.8/10 Excellent! (1,065 reviews)
Super close to the center. Great Breakfast. Clean room and very friendly staff. However, it would be most likely cheaper to buy breakfast the day off then prepay while booking. I got vouchers because I paid for breakfast in advance but could see what my bill would have been and I paid more when booking the room.

Reviewed on Mar 16, 2026

The Cheshire

The Cheshire

4 out of 5
Price was $734, price is now $575 per person
$575
per person
May 28 - May 31
found 20 hours ago
Roundtrip flight included
New York (NYC) to St. Louis (STL)
8.6/10 Excellent! (1,009 reviews)
Bar and restaurant were both great!

Reviewed on Mar 9, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Price was $1,034, price is now $827 per person
$827
per person
Apr 22 - Apr 26
found 1 day ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
8.4/10 Very Good! (1,000 reviews)
Rooms are spacious.

Reviewed on Mar 20, 2026

Where to stay in St. John

Find the best St. John areas and neighborhoods for the activities you enjoy most. Learn more about St. John
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

3 out of top 10 points of interest in this area
4/5(4,014 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

St. John Hotel Deals

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $189 total per night from Mar 29 to Mar 30
$189 total
Mar 29 - Mar 30
Total with taxes and fees
9.4/10 Exceptional! (3,348 reviews)
Yes

Reviewed on Mar 20, 2026

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $124 total per night from Apr 5 to Apr 6
$124 total
Apr 5 - Apr 6
Total with taxes and fees
8.8/10 Excellent! (1,876 reviews)
The hotel was nice and clean with good amenities of free breakfast and drinks each day. Parking was easy and free. It was super convenient and close to all the kids activities (City Museum, Arch, Zoo, etc). The blackout curtains in the room actually worked! We happened here during spring break when ...

Reviewed on Mar 20, 2026

Pear Tree Inn St. Louis Near Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Apr 19 to Apr 20
$110 total
Apr 19 - Apr 20
Total with taxes and fees
8.8/10 Excellent! (3,116 reviews)
The staff was appoligetic, but there was ledt over insulin medication in the and left over food in the fridge. Plus a left over bowl with dried blood from the blood checker. Also the shower head was not working it needed to be reset as soon as we got their. Then it went out again by morning.

Reviewed on Mar 20, 2026

Clayton Plaza Hotel & Extended Stay
See all 1,909 properties in St. John
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
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Beach Vacations
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Kid Friendly Vacations

Discover the most popular places to visit in St. John

Union Station, St. Louis, MO

St. Louis Union Station

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

St. Louis Union Station
St. Louis Cardinals Baseball.

Busch Stadium

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.

Busch Stadium
Gateway Arch showing a city, a skyscraper and skyline

Gateway Arch

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

$30
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
St. Louis Premium Driving Tour with Boat Ride & Arch

St. Louis Premium Driving Tour with Boat Ride & Arch

$174
per adult
100% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.