St. John Vacations from $387

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Your St. John Vacation

From its highlights to its hidden gems, this city is best explored with a St. John vacation package. Check out hotels located in Downtown St. Louis, which is great for festivals, bars and pubs and dining. Make your trip to St. John even more enjoyable by going sightseeing. St. Louis Zoo, St. Louis Art Museum and Washington University in St. Louis are some of the most popular attractions you'll want to explore. Whatever your travel plans or budget, organizing a tailored St. John vacation is a cinch with Expedia.

The Latest St. John Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $647, price is now $387 per person
$387
per person
Mar 26 - Mar 29
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Very cute place, recently updated clean and comfortable.

Reviewed on Jan 19, 2026

Landing Apartments - Eureka

Landing Apartments - Eureka

4 out of 5
Save 100% on your flight
Price was $1,017, price is now $739 per person
$739
per person
Mar 12 - Mar 16
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to St. Louis (STL)
No reviews
Spacious 3-Bedroom with King Bed

Spacious 3-Bedroom with King Bed

4 out of 5
Central West End
Save 100% on your flight
Price was $950, price is now $721 per person
$721
per person
Mar 12 - Mar 16
found 22 hours ago
Roundtrip flight included
Minneapolis (MSP) to St. Louis (STL)
8.6/10 Excellent! (10 reviews)
Overall, we loved the apartment. It was cute, beds were very comfortable.

Reviewed on May 8, 2025

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG

2.5 out of 5
Price was $631, price is now $496 per person
$496
per person
Mar 12 - Mar 16
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to St. Louis (STL)
9.4/10 Exceptional! (688 reviews)
Checking in was a great experience, the staff was very friendly and gave us a warm greeting. The room was very clean and smelled great. The beds were beyond comfortable. We were able to get a large room for multiple people. I would recommend this hotel and will definitely stay there again if I am around that area again.

Reviewed on Jan 19, 2026

Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG

3.5 out of 5
Central West End
Price was $644, price is now $510 per person
$510
per person
Mar 12 - Mar 16
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to St. Louis (STL)
8.2/10 Very Good! (1,000 reviews)
Room was super clean, bed was comfy and staff was very nice and helpful. I would definitely stay there again.

Reviewed on Jan 12, 2026

Where to stay in St. John

Find the best St. John areas and neighborhoods for the activities you enjoy most. Learn more about St. John
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

4 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

St. John Hotel Deals

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Feb 10 to Feb 11
$173 total
Feb 10 - Feb 11
Total with taxes and fees
9/10 Wonderful! (1,560 reviews)
Great hotel! Art, food and drinks were fantastic

Reviewed on Jan 18, 2026

21C Museum Hotel St Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $176 total per night from Jan 24 to Jan 25
$176 total
Jan 24 - Jan 25
Total with taxes and fees
8.4/10 Very Good! (4,046 reviews)
There was still an old coffee pod in the coffee maker. Hotels are creepy and weird. This one wasn’t any different. The view was nice. The beds and bathroom were clean.

Reviewed on Jan 19, 2026

Hyatt Regency St. Louis at The Arch
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $104 total per night from Jan 25 to Jan 26
$104 total
Jan 25 - Jan 26
Total with taxes and fees
8.6/10 Excellent! (1,202 reviews)
Everything was great the customer service rep at the desk exceptional customer service.

Reviewed on Jan 18, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
See all 1,858 properties in St. John
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in St. John

Union Station, St. Louis, MO

St. Louis Union Station

4/5(615 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed art scene or attend a baseball game.

St. Louis Union Station
St. Louis Cardinals Baseball.

Busch Stadium

4.5/5(1,469 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Busch Stadium
Gateway Arch showing a city, a skyscraper and skyline

Gateway Arch

4.5/5(2,511 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$32
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis Premium Driving Tour with Boat Ride & Arch

St. Louis Premium Driving Tour with Boat Ride & Arch

$174
per adult
100% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

$169
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.