Tower Grove South Vacations from $326

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Your Tower Grove South Vacation

With a personalized vacation package to Tower Grove South, you can spend less time planning and more time uncovering this appealing neighborhood. From its shopping to its distilleries and craft breweries, there's so much to discover here. Not sure where to go during your trip to Tower Grove South? Nearby attractions such as Missouri Botanical Gardens and Arboretum, Anheuser-Busch Brewery and Forest Park are good places to begin. Expedia will help you turn your dream Tower Grove South vacation into reality, no matter your budget or travel plans.

The Latest Tower Grove South Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Riverside Inn Hannibal

Riverside Inn Hannibal

2.5 out of 5
Save 100% on your flight
Price was $506, price is now $326 per person
$326
per person
Jan 23 - Jan 25
found 1 day ago
Roundtrip flight included
Chicago (CHI) to St. Louis (STL)
9.4/10 Exceptional! (162 reviews)
Clean, spacious room with a big desk; fully functional kitchen (full size fridge, stove, dishwasher, dishes, pots and pans); large walk-in shower; and comfortable bed. Quiet (unlike larger chain hotels). Great view of the river. Delicious Mexican food downstairs. 11/10, will stay here again.

Reviewed on Nov 23, 2025

Hermann Grain Bins BNB

Hermann Grain Bins BNB

2 out of 5
Save 100% on your flight
Price was $1,849, price is now $1,105 per person
$1,105
per person
Feb 14 - Feb 21
found 1 day ago
Roundtrip flight included
Chicago (ORD) to St. Louis (STL)
2/10 (1 review)
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $846, price is now $517 per person
$517
per person
Jan 8 - Jan 12
found 4 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
The hot tub didnt work. It didnt have the table arrangement as advertised in the picture. The suite was very small.

Reviewed on Nov 28, 2025

HoteLumiere at the Arch - A Caesars Rewards Destination

HoteLumiere at the Arch - A Caesars Rewards Destination

4 out of 5
Downtown St. Louis
Save 100% on your flight
Price was $881, price is now $572 per person
$572
per person
Jan 8 - Jan 12
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to St. Louis (STL)
6.6/10 (1,001 reviews)
It was very nice resort

Reviewed on Nov 20, 2025

Comfort Inn Sullivan

Comfort Inn Sullivan

2.5 out of 5
Save 100% on your flight
Price was $626, price is now $438 per person
$438
per person
Feb 14 - Feb 21
found 1 day ago
Roundtrip flight included
Chicago (ORD) to St. Louis (STL)
8.6/10 Excellent! (798 reviews)
The staff was very friendly and the rooms were very clean.

Reviewed on Nov 28, 2025

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Where to stay in Tower Grove South

Find the best Tower Grove South areas and neighborhoods for the activities you enjoy most. Learn more about Tower Grove South
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

3 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

Tower Grove South Hotel Deals

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $120 total per night from Dec 8 to Dec 9
$120 total
Dec 8 - Dec 9
Total with taxes and fees
8.6/10 Excellent! (1,129 reviews)
Extremely welcoming and engaging staff made check in so positive. Room was clean and lovely except for a heating issue, which staff politely addressed but the heating never really warmed up beyond 65 degrees.

Reviewed on Nov 27, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Dec 4 to Dec 5
$106 total
Dec 4 - Dec 5
Total with taxes and fees
9.2/10 Wonderful! (2,749 reviews)
Staff was very helpful. Thanks.

Reviewed on Nov 27, 2025

Pear Tree Inn St. Louis Airport
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $111 total per night from Dec 21 to Dec 22
$111 total
Dec 21 - Dec 22
Total with taxes and fees
8.4/10 Very Good! (4,006 reviews)
Taylor, at the front desk, was amazing and so helpful. She answered my questions with ease during check-in, and continued to help throughout my stay. Taylor deserves a huge Thank you!

Reviewed on Nov 22, 2025

Hyatt Regency St. Louis at The Arch
See all 1,789 properties in Tower Grove South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Tower Grove South

St. Louis Union Station

St. Louis Union Station

4/5(615 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

St. Louis Union Station
Gateway Arch showing a city, a skyscraper and skyline

Gateway Arch

4.5/5(2,511 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

4.5/5(1,212 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$32
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
Step into the shadows and discover the haunting tales of our city's past.

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

$30
per adult
100% of travellers recommend
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

$169
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.