Unión Santeña Vacations from $657

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The Latest Unión Santeña Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Dec 26 - Dec 30

    Casa La Costa By Wynwood House + Flight

    Casco Viejo
    4 nights
    3.5 star property
    7.8/10 - Good (35 reviews)
    "The bed was fine, but the closet and the floor were quite dirty. There was also an unpleasant smell in my room."
    Reviewed July 25, 2026
    Roundtrip • Georgetown (GEO) - Panama City (PTY)
    GEO - PTY • Nonstop PTY - GEO • Nonstop
    $947
    $657
    per traveler
    found 17 hours ago
    Casa La Costa By Wynwood House
  • Jan 7 - Jan 12

    Megapolis Hotel Panamá + Flight

    San Francisco
    5 nights
    4.5 star property
    8.6/10 - Excellent (1,876 reviews)
    "The property is beautiful, the breakfast 9.8/10. The staff very friendly. Room was super clean! I'm already planning my trip there for next year."
    Reviewed November 13, 2026
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,886
    $1,112
    per traveler
    found 1 day ago
    Megapolis Hotel Panamá
  • Dec 31 - Jan 4

    Casa Lefevre By Wynwood House + Flight

    Casco Viejo
    4 nights
    3.0 star property
    9.6/10 - Exceptional (16 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $4,189
    $2,499
    per traveler
    found 8 hours ago
    Casa Lefevre By Wynwood House
  • Jan 30 - Feb 3

    Casa Mallet by Wynwood House + Flight

    Casco Viejo
    4 nights
    3.5 star property
    9.8/10 - Exceptional (31 reviews)
    "I would highly recommend, the service I received was impeccable and just a wonderful experience! I was a bit hesitant regarding the location but once I got there, it turned out to be perfect. The concierge staff was such a pleasure to work with especially ‘Jerry’, who provided recommendations and information. This was such a blessing to us. I would stay here again in a heart beat. It’s a must stay!"
    Reviewed September 16, 2026
    Roundtrip • Miami (MIA) - Panama City (PTY)
    MIA - PTY • Nonstop PTY - MIA • Nonstop
    $2,546
    $1,562
    per traveler
    found 9 hours ago
    Casa Mallet by Wynwood House
  • Jan 4 - Jan 7

    Las Clementinas + Flight

    Casco Viejo
    3 nights
    3.5 star property
    9.4/10 - Exceptional (208 reviews)
    "Beautiful property and great restaurant! Also awesome customer service"
    Reviewed November 7, 2026
    Roundtrip • Miami (MIA) - Panama City (PTY)
    MIA - PTY • Nonstop PTY - MIA • Nonstop
    $1,394
    $971
    per traveler
    found 1 day ago
    Las Clementinas

Frequently Asked Questions

How to find the best Unión Santeña package deals?

Use Expedia's handy filters to help you find some of the best Unión Santeña package deals. When you begin your search, simply set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your break for midweek, or look for Unión Santeña package deals in the off-season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.

When to book a vacation package to Unión Santeña?

If you have your Unión Santeña travel dates confirmed, book early to bag some awesome deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are great for impromptu escapes.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.