Title: Unión Santeña Vacation Packages 2026 from $687 | Expedia.com

[Unión Santeña Travel Guide](https://expedia.com/Union-Santena.dx829297590047612928)[Hotels in Unión Santeña](https://expedia.com/Union-Santena-Hotels.d829297590047612928.Travel-Guide-Hotels)[Vacation Rentals in Unión Santeña](https://expedia.com/Union-Santena-Vacation-Rentals.d829297590047612928.Travel-Guide-VacationRentals)[Flights to Unión Santeña](https://expedia.com/Cheap-Flights-To-Union-Santena.d829297590047612928.Travel-Guide-Flights)[Car Rentals in Unión Santeña](https://expedia.com/Car-Rentals-In-Union-Santena.d829297590047612928.Car-Rental-Guide)

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# Unión Santeña Vacations from $687

## Book a Hotel + Flight or Car together to unlock savings

- ##  
Plan, book, travel with confidence
- ###  
Better together  
Save up to $1,045 when you book a flight and hotel together\*
- ###  
Find the right fit  
With over 300,000 hotels worldwide, it's easy to create a perfect package
- ###  
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Plan, book, and manage your trip all in one place

## The Latest Unión Santeña vacation packages

Price found within the past 48 hours. Click for updated prices.

![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Villa Botero By Casa Mojito B&B

Save 100% on your flight

$687

per person

May 4 - May 11

found 1 day ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

9.8/10 Exceptional! (60 reviews)

We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time.

Reviewed on Jan 22, 2026

![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,472

per person

May 1 - May 8

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

9/10 Wonderful! (1,002 reviews)

Room was amazing, beautiful hotel in the center of town. Service also very good and attentive. Amazing breakfast.

Reviewed on Feb 24, 2026

![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Megapolis Hotel Panamá

San Francisco

Save 100% on your flight

$1,327

per person

May 1 - May 8

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

8.4/10 Very Good! (1,204 reviews)

The room was excellent served was excellent. Everything was 100% service breakfast pool rooms view 10+ I strongly recommend this hotel. They grows in the breakfast, Melissa. Magella list Daniela Monica, the pool, amazing amazing girls. They were so helpful and caring all the way. The courtesy was amazing.

Reviewed on Feb 24, 2026

![Playa Caracol Residences Vacation Rental](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/d7354164_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Playa Caracol Residences Vacation Rental

$964

per person

Mar 31 - Apr 6

found 1 day ago

Roundtrip flight included

New York (NYC) to Panama City (PTY)

7.2/10 Good! (26 reviews)

Great, clean condo overlooking the pool and ocean. We didn't cook our meals, but used the restaurant on site. Staff was friendly and professional.

Reviewed on Dec 7, 2025

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Riu Plaza Panama

Bella Vista

$899

per person

May 1 - May 8

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

9/10 Wonderful! (4,515 reviews)

The staff was very kind and meet our needs even with the language barrier The breakfast wasnt what others bragged about but still we were able to fill up each morning The cafe was a nice bonus And lastly the pool area was so soothing nice chill spot not to party crazy but still a Dj played each afternoon also the poolside meals were excellent 👌

Reviewed on Feb 26, 2026

Don't see what you're looking for?

See all available trips from Columbus to Unión Santeña

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-26/2026-04-02/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=IVI&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_829297590047612928)

## Unión Santeña Hotel Deals

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

Fully refundableReserve now, pay when you stay

$138 nightly

$151 total

Mar 8 - Mar 9

Total with taxes and fees

9/10 Wonderful! (5,015 reviews)

Nice

Reviewed on Feb 26, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=3900395&PinnedHotelID=3900395&HadPinnedHotel=true&regionId=829297590047612928)

![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama

Fully refundableReserve now, pay when you stay

$108 nightly

$119 total

Mar 23 - Mar 24

Total with taxes and fees

7.8/10 Good! (1,026 reviews)

Yes greet staff jefeth in front desk, good food, good pool

Reviewed on Feb 25, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F23%2F2026&endDate=3%2F24%2F2026&selected=7164&PinnedHotelID=7164&HadPinnedHotel=true&regionId=829297590047612928)

![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama

Fully refundable

$115 nightly

$127 total

Mar 5 - Mar 6

Total with taxes and fees

8.6/10 Excellent! (2,462 reviews)

It was just to over night

Reviewed on Feb 26, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&selected=8836117&PinnedHotelID=8836117&HadPinnedHotel=true&regionId=829297590047612928)

[See all 1,461 properties in Panamá Province](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F27%2F2026&endDate=2%2F28%2F2026&regionId=6246281)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Find the Best Unión Santeña Vacation Packages

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## Frequently asked questions

### How to find the best Unión Santeña package deals?

### When to book a vacation package to Unión Santeña?

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

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