University City Vacations from $395

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Your University City Vacation

Book an University City vacation package and experience the rhythm and vibe of this sought-after neighborhood. With all your travel plans worked out, the only thing you need to focus on here is having a good time. Eager to head out and see the sights during your trip to University City? Make sure you check out nearby attractions such as St. Louis Art Museum, Washington University in St. Louis and Saint Louis Galleria Mall. Expedia is here to put your plans into action. Book your ideal University City vacation today.

The Latest University City Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $567, price is now $395 per person
$395
per person
Mar 27 - Mar 29
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Everything was great

Reviewed on Feb 23, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
Grand Center
Price was $665, price is now $495 per person
$495
per person
Apr 27 - Apr 30
found 5 hours ago
Roundtrip flight included
Las Vegas (LAS) to St. Louis (STL)
8.8/10 Excellent! (1,022 reviews)
Great customer service. The locals there are friendly as well as the staff members

Reviewed on Feb 23, 2026

Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

3 out of 5
Downtown West
Price was $589, price is now $464 per person
$464
per person
Apr 27 - Apr 30
found 5 hours ago
Roundtrip flight included
Las Vegas (LAS) to St. Louis (STL)
8/10 Very Good! (567 reviews)
Our room was clean and very comfortable. Warm water was very slow to arrive in the shower (5 minutes) and then it was lukewarm. The elevators were a problem. Only one working with a full hotel. Breakfast was decent .

Reviewed on Feb 17, 2026

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

4 out of 5
Central West End
Price was $614, price is now $490 per person
$490
per person
Apr 27 - Apr 30
found 5 hours ago
Roundtrip flight included
Las Vegas (LAS) to St. Louis (STL)
8.2/10 Very Good! (1,003 reviews)
The room was clean and comfortable, the staff was friendly and accommodating. Perfect for our stay!

Reviewed on Feb 24, 2026

Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport

2.5 out of 5
Woodson Terrace
Price was $579, price is now $466 per person
$466
per person
Apr 27 - Apr 30
found 5 hours ago
Roundtrip flight included
Las Vegas (LAS) to St. Louis (STL)
8.8/10 Excellent! (96 reviews)
The staff does not tell you that they only clean rooms every other day. I had to send for more towels and tissue. Otherwise the stay was fine. Also there is no laundry.

Reviewed on Feb 24, 2026

Where to stay in University City

Find the best University City areas and neighborhoods for the activities you enjoy most. Learn more about University City
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

4 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

University City Hotel Deals

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$94 nightly
The price is $110 total per night from Mar 2 to Mar 3
$110 total
Mar 2 - Mar 3
Total with taxes and fees
8.8/10 Excellent! (1,845 reviews)
The staff at check in was very nice. The rooms were great!

Reviewed on Feb 25, 2026

Pear Tree Inn St. Louis Near Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
$131 nightly
The price is $153 total per night from Mar 23 to Mar 24
$153 total
Mar 23 - Mar 24
Total with taxes and fees
9/10 Wonderful! (1,619 reviews)
Yes

Reviewed on Feb 24, 2026

21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $125 total per night from Mar 1 to Mar 2
$125 total
Mar 1 - Mar 2
Total with taxes and fees
8.8/10 Excellent! (3,084 reviews)
The staff was kind and responsive to questions and concerns. However, the hotel.feels ready for a significant update. In the hallways and our room had very strong aromas of disinfectant and deodorizors. We got a new room when we shared that the intense odor challenged our asthma.

Reviewed on Feb 23, 2026

Clayton Plaza Hotel & Extended Stay
See all 1,900 properties in University City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in University City

St. Louis Walk of Fame

You can spend an afternoon studying the exhibits at St. Louis Walk of Fame in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

St. Louis Walk of Fame

Tivoli Theatre

You can get tickets for a performance at Tivoli Theatre on your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Tivoli Theatre

Componere Gallery

You can spend an afternoon studying the exhibits at Componere Gallery during your travels in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Componere Gallery

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$32
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

$27
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
St. Louis Premium Driving Tour with Boat Ride & Arch

St. Louis Premium Driving Tour with Boat Ride & Arch

$174
per adult
100% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.