University City Vacations from $258

Book a Hotel + Flight or Car together to unlock savings

Photo by HA

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your University City Vacation

Book an University City vacation package and experience the rhythm and vibe of this sought-after neighborhood. With all your travel plans worked out, the only thing you need to focus on here is having a good time. Eager to head out and see the sights during your trip to University City? Make sure you check out nearby attractions such as St. Louis Art Museum, Washington University in St. Louis and Saint Louis Galleria Mall. Expedia is here to put your plans into action. Book your ideal University City vacation today.

The Latest University City Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $514, price is now $258 per person
$258
per person
Mar 26 - Mar 29
found 24 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Clean room and a vwey nice rom too.

Reviewed on Feb 1, 2026

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $512, price is now $359 per person
$359
per person
Mar 26 - Mar 29
found 24 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,002 reviews)
The Cheshire is in a class by itself. The halls and sitting areas are so full of history and there’s an ambiance that we just love. Our suite, Treasure Island, was amazing! Large, clean, luxurious and cozy with a beautiful fireplace and large jacuzzi. We had a delicious dinner at the Basso, relaxed in the very British, cozy Fox & Hound, enjoyed a coffee at the Tudor styled Starbucks and as always, enjoyed breakfast beside the fireplace. We loved our stay!

Reviewed on Jan 28, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
Grand Center
Save 100% on your flight
Price was $474, price is now $345 per person
$345
per person
Mar 26 - Mar 29
found 24 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,022 reviews)
Clean room and great staff

Reviewed on Jan 27, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Save 100% on your flight
Price was $546, price is now $402 per person
$402
per person
Mar 26 - Mar 29
found 24 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.4/10 Very Good! (1,006 reviews)
I booked this hotel mainly for the pool and hot tub for a girls’ night. Check-in was at 4, and we were surprised to find out the hot tub closed at 6. Most hotels we’ve stayed at keep their pool areas open until 9 or 10, so this was a little disappointing.

Reviewed on Jan 18, 2026

Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
Price was $354, price is now $268 per person
$268
per person
Mar 26 - Mar 29
found 24 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.2/10 Very Good! (779 reviews)
Staff was informative during check-in. Room was clean and the TV even had WELCOME with my name on it. Would stay here again.

Reviewed on Dec 22, 2025

Where to stay in University City

Find the best University City areas and neighborhoods for the activities you enjoy most. Learn more about University City
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

4 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

University City Hotel Deals

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Feb 22 to Feb 23
$153 total
Feb 22 - Feb 23
Total with taxes and fees
9/10 Wonderful! (1,581 reviews)
Very nice and clean

Reviewed on Jan 29, 2026

21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $116 total per night from Feb 8 to Feb 9
$116 total
Feb 8 - Feb 9
Total with taxes and fees
8.8/10 Excellent! (3,081 reviews)
Lovely hotel. Great breakfast

Reviewed on Jan 29, 2026

Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $176 total per night from Feb 28 to Mar 1
$176 total
Feb 28 - Mar 1
Total with taxes and fees
8.4/10 Very Good! (4,037 reviews)
Just had a do barking in the next room

Reviewed on Jan 27, 2026

Hyatt Regency St. Louis at The Arch
See all 1,878 properties in University City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in University City

Tivoli Theatre

You can get tickets for a performance at Tivoli Theatre on your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Tivoli Theatre

St. Louis Walk of Fame

You can spend an afternoon studying the exhibits at St. Louis Walk of Fame in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

St. Louis Walk of Fame

Componere Gallery

You can spend an afternoon studying the exhibits at Componere Gallery during your travels in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Componere Gallery

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$32
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

$169
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
St. Louis Premium Driving Tour with Boat Ride & Arch

St. Louis Premium Driving Tour with Boat Ride & Arch

$174
per adult
100% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.