University City Vacations from $328

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Your University City Vacation

Book an University City vacation package and experience the rhythm and vibe of this sought-after neighborhood. With all your travel plans worked out, the only thing you need to focus on here is having a good time. Eager to head out and see the sights during your trip to University City? Make sure you check out nearby attractions such as St. Louis Art Museum, Washington University in St. Louis and Saint Louis Galleria Mall. Expedia is here to put your plans into action. Book your ideal University City vacation today.

The Latest University City Vacation Packages

Price found within the past 48 hours. Click for updated prices.
White House at Grand Central

White House at Grand Central

4 out of 5
Grand Center
Price was $462, price is now $328 per person
$328
per person
Apr 1 - Apr 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (123 reviews)
Very clean and very friendly people

Reviewed on Nov 11, 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $642, price is now $356 per person
$356
per person
Apr 1 - Apr 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Room was clean and big with a separate sitting area. We would definitely stay there again .

Reviewed on Jan 21, 2026

The Cheshire

The Cheshire

4 out of 5
Price was $561, price is now $434 per person
$434
per person
Apr 1 - Apr 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,002 reviews)
There was a bolier breakdown so there was no hot water on the property the last night of our stay, making a shower rather unpleasant. There were some obsrved maintenance issues in the fitness room: dumbbell sets over 35 lb. were missing, there were no towels or wipes to wipe down equipment, the trash can was overflowing in the men’s restroom, with trash on the floor, and there was little to no bottled water available the last 2 days of the stay. The breakfast was good as always, with berries every day, and the personnel were generally responsive to our requests.

Reviewed on Jan 20, 2026

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
Downtown West
Price was $456, price is now $352 per person
$352
per person
Apr 1 - Apr 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (1,458 reviews)
Great staff, cool amenities, amazing environment. We had a lot of fun with the penguins! ;)

Reviewed on Jan 19, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Price was $585, price is now $453 per person
$453
per person
Apr 1 - Apr 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.4/10 Very Good! (1,006 reviews)
I booked this hotel mainly for the pool and hot tub for a girls’ night. Check-in was at 4, and we were surprised to find out the hot tub closed at 6. Most hotels we’ve stayed at keep their pool areas open until 9 or 10, so this was a little disappointing.

Reviewed on Jan 18, 2026

Where to stay in University City

Find the best University City areas and neighborhoods for the activities you enjoy most. Learn more about University City
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

4 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

University City Hotel Deals

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Feb 22 to Feb 23
$173 total
Feb 22 - Feb 23
Total with taxes and fees
9/10 Wonderful! (1,560 reviews)
Great hotel! Art, food and drinks were fantastic

Reviewed on Jan 18, 2026

21C Museum Hotel St Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $176 total per night from Jan 24 to Jan 25
$176 total
Jan 24 - Jan 25
Total with taxes and fees
8.4/10 Very Good! (4,026 reviews)
Very clean rooms the staff was excellent and ver helpful and friendly. Being so close to the arch was wonderful for views at night 100/10 recommend

Reviewed on Jan 20, 2026

Hyatt Regency St. Louis at The Arch
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $104 total per night from Jan 25 to Jan 26
$104 total
Jan 25 - Jan 26
Total with taxes and fees
8.6/10 Excellent! (1,202 reviews)
Everything was great the customer service rep at the desk exceptional customer service.

Reviewed on Jan 18, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
See all 1,871 properties in University City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in University City

Tivoli Theatre

4.5/5(4 reviews)

You can get tickets for a performance at Tivoli Theatre on your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Tivoli Theatre

St. Louis Walk of Fame

You can spend an afternoon studying the exhibits at St. Louis Walk of Fame in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

St. Louis Walk of Fame

Componere Gallery

You can spend an afternoon studying the exhibits at Componere Gallery during your travels in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Componere Gallery

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$32
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis Premium Driving Tour with Boat Ride & Arch

St. Louis Premium Driving Tour with Boat Ride & Arch

$174
per adult
100% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

$169
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.