University City Vacations from $319

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Your University City Vacation

Book an University City vacation package and experience the rhythm and vibe of this sought-after neighborhood. With all your travel plans worked out, the only thing you need to focus on here is having a good time. Eager to head out and see the sights during your trip to University City? Make sure you check out nearby attractions such as St. Louis Art Museum, Washington University in St. Louis and Saint Louis Galleria Mall. Expedia is here to put your plans into action. Book your ideal University City vacation today.

The Latest University City Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

Midtown
Save 100% on your flight
$319
per person
Dec 3 - Dec 7
found 17 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
7.8/10 Good! (1,002 reviews)
The Wildwood Hotel

The Wildwood Hotel

Save 100% on your flight
$359
per person
Dec 3 - Dec 7
found 18 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,672 reviews)
Clean friendly secure

Reviewed on Sep 28, 2026

Moonrise Hotel

Moonrise Hotel

Delmar Loop
Save 100% on your flight
$421
per person
Dec 3 - Dec 7
found 17 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (2,016 reviews)
Good Rooftop experience friendly staff

Reviewed on Sep 28, 2026

The Knight Center at Washington University

The Knight Center at Washington University

Save 100% on your flight
$385
per person
Dec 3 - Dec 7
found 17 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.4/10 Exceptional! (668 reviews)
The Cheshire

The Cheshire

Save 100% on your flight
$474
per person
Dec 3 - Dec 7
found 17 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,004 reviews)
The staff, lobby, breakfast were all good. The room was mid-tier, however. Not bad, but still a bit pricey for what it was.

Reviewed on Sep 28, 2026

Where to stay in University City

Find the best University City areas and neighborhoods for the activities you enjoy most. Learn more about University City
A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis

4 out of top 10 points of interest in this area

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis
The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Find hotels in Clayton
A street with parked cars, a building with a sign reading "Brennan's", and a tree in front.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Find hotels in Central West End
A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Find hotels in St. Charles Historic District
A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Find hotels in Creve Coeur

University City Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$92 nightly
$108 total
Oct 11 - Oct 12
Total with taxes and fees
8.8/10 Excellent! (3,444 reviews)
"The parking garage wasn't as easy to find as I thought. I should have checked in first then gotten parking info. Clean, quiet and very safe. Walkable to restaurants. Staff was helpful and friendly."

Reviewed on Sep 28, 2026

Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$134 nightly
$158 total
Oct 2 - Oct 3
Total with taxes and fees
8.6/10 Excellent! (4,323 reviews)
"Great stay with a great view and amenities…."

Reviewed on Sep 28, 2026

Hyatt Regency St. Louis at The Arch
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
$106 total
Oct 4 - Oct 5
Total with taxes and fees
Pear Tree Inn St. Louis Airport
See all 2,012 properties in University City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular University City attractions

Center of Creative Arts

Enjoy an outing to Center of Creative Arts during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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St. Louis Black Repertory Company

You can get tickets for a performance at St. Louis Black Repertory Company during your stay in St. Louis. Visit the shops in this family-friendly area, or simply enjoy its restaurants.
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Tivoli Theatre

9.0/10 (4 reviews)
You can get tickets for a performance at Tivoli Theatre on your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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St. Louis Walk of Fame

You can spend an afternoon studying the exhibits at St. Louis Walk of Fame in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Heman Park Tennis Center

Catch an event at Heman Park Tennis Center during your trip to St. Louis. Visit the shops in this family-friendly area, or simply enjoy its restaurants.
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Componere Gallery

You can spend an afternoon studying the exhibits at Componere Gallery during your travels in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
Self Guided Walking & Driving Audio Tour St. Louis

Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP

$15
per traveler
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

$25
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.