University City Vacations from $295

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Your University City Vacation

Book an University City vacation package and experience the rhythm and vibe of this sought-after neighborhood. With all your travel plans worked out, the only thing you need to focus on here is having a good time. Eager to head out and see the sights during your trip to University City? Make sure you check out nearby attractions such as St. Louis Art Museum, Washington University in St. Louis and Saint Louis Galleria Mall. Expedia is here to put your plans into action. Book your ideal University City vacation today.

The Latest University City Vacation Packages

Price found within the past 48 hours. Click for updated prices.
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
Downtown West
Save 100% on your flight
Price was $404, price is now $295 per person
$295
per person
Sep 3 - Sep 7
found 1 hour ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (1,912 reviews)
Amazing front desk staff. Courteous and attentive. Beautiful and clean property. Highly recommended.

Reviewed on Jun 18, 2026

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $751, price is now $342 per person
$342
per person
Sep 3 - Sep 7
found 1 hour ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,667 reviews)
Rooms were spacious and clean, staff was warm and welcoming, breakfast options were limited but available if needed, and free covered parking with direct access to the hotel was available, which was perfect when storms rolled thru the night we stayed. Highly recommend the hotel for anyone visiting the St. Louis metro area.

Reviewed on Jun 19, 2026

Moonrise Hotel

Moonrise Hotel

4 out of 5
Delmar Loop
Save 100% on your flight
Price was $452, price is now $310 per person
$310
per person
Sep 15 - Sep 18
found 4 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (1,981 reviews)
Rooftop bar was the icing on the cake after a long night put at a concert. Can also smoke put there iykyk

Reviewed on Jun 20, 2026

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $430, price is now $312 per person
$312
per person
Sep 15 - Sep 18
found 4 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,016 reviews)
Hi-Point best neighborhood, near the park

Reviewed on Jun 16, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
Grand Center
Save 100% on your flight
Price was $473, price is now $344 per person
$344
per person
Sep 15 - Sep 18
found 4 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,067 reviews)
Room was clean. When I checked in Tia was very a treat and very helpful about the amenities close by. The rooftop bar is great. Josie and Colton are both great bartenders and very personable.

Reviewed on Jun 21, 2026

Where to stay in University City

Find the best University City areas and neighborhoods for the activities you enjoy most. Learn more about University City
Downtown St. Louis

Downtown St. Louis

2 out of top 10 points of interest in this area
4/5(4,044 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

University City Hotel Deals

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $169 total per night from Jun 28 to Jun 29
$169 total
Jun 28 - Jun 29
Total with taxes and fees
8.6/10 Excellent! (4,136 reviews)
"Great"

Reviewed on Jun 21, 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $108 total per night from Jul 19 to Jul 20
$108 total
Jul 19 - Jul 20
Total with taxes and fees
8.8/10 Excellent! (3,249 reviews)
"Check in was fast and easy. The restaurant is only open for breakfast. The buffet was good! We wish they were open for dinner also but the hotel is close to restaurants in walking distance"

Reviewed on Jun 20, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $104 total per night from Jun 29 to Jun 30
$104 total
Jun 29 - Jun 30
Total with taxes and fees
9.4/10 Exceptional! (3,036 reviews)
"Na"

Reviewed on Jun 21, 2026

Pear Tree Inn St. Louis Airport
See all 1,905 properties in University City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in University City

Tivoli Theatre

You can get tickets for a performance at Tivoli Theatre on your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Tivoli Theatre

St. Louis Walk of Fame

You can spend an afternoon studying the exhibits at St. Louis Walk of Fame in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

St. Louis Walk of Fame

Componere Gallery

You can spend an afternoon studying the exhibits at Componere Gallery during your travels in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Componere Gallery

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
Best of St. Louis Small Group Tour w/ Arch & River Cruise

St. Louis Premium Small Group Tour With Arch & River Cruise

$161
per adult
84% of travellers recommend
St. Louis Premium Small Group Tour With Arch & River Cruise
St. Louis Premium Driving Tour with Boat Ride & Arch

St. Louis Premium Driving Tour with Boat Ride & Arch

$174
per adult
100% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.