University City Vacations from $277

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Your University City Vacation

Book an University City vacation package and experience the rhythm and vibe of this sought-after neighborhood. With all your travel plans worked out, the only thing you need to focus on here is having a good time. Eager to head out and see the sights during your trip to University City? Make sure you check out nearby attractions such as St. Louis Art Museum, Washington University in St. Louis and Saint Louis Galleria Mall. Expedia is here to put your plans into action. Book your ideal University City vacation today.

The Latest University City Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
Save 100% on your flight
Price was $378, price is now $277 per person
$277
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.2/10 Very Good! (779 reviews)
Staff was informative during check-in. Room was clean and the TV even had WELCOME with my name on it. Would stay here again.

Reviewed on Dec 22, 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $712, price is now $353 per person
$353
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Clean room and easy parking.

Reviewed on Feb 2, 2026

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $495, price is now $362 per person
$362
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,002 reviews)
I love the whole "English Tudor" vibe at the hotel. The room was clean and well-appointed. The staff is friendly and the hotel lounge is a fun place to unwind.

Reviewed on Feb 6, 2026

Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection

4 out of 5
Downtown St. Louis
Save 100% on your flight
Price was $573, price is now $420 per person
$420
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (458 reviews)
Property and room was really nice. I will be staying here in the future

Reviewed on Nov 25, 2025

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Save 100% on your flight
Price was $540, price is now $397 per person
$397
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.4/10 Very Good! (1,006 reviews)
The room was spotless and the employees went above and beyond for my fiancée and I. It was a wonderful stay and we look forward to staying again in the future. There is lots of food to choose from at Ameristar. Not to mention there is lots of fun to be had. We personally played the slots, ate dinner before that and after all of that we enjoyed the sparkling clean pool and hot tub at the hotel. It waa a wonderful stay and we definitely look forward to staying again.

Reviewed on Feb 6, 2026

Where to stay in University City

Find the best University City areas and neighborhoods for the activities you enjoy most. Learn more about University City
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

4 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

University City Hotel Deals

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $162 total per night from Feb 22 to Feb 23
$162 total
Feb 22 - Feb 23
Total with taxes and fees
9/10 Wonderful! (1,594 reviews)
Everything was great i can’t wait to stay again

Reviewed on Feb 6, 2026

21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $112 total per night from Feb 8 to Feb 9
$112 total
Feb 8 - Feb 9
Total with taxes and fees
8.8/10 Excellent! (3,083 reviews)
Staff always pleasant

Reviewed on Feb 2, 2026

Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $152 total per night from Feb 28 to Mar 1
$152 total
Feb 28 - Mar 1
Total with taxes and fees
8.4/10 Very Good! (4,017 reviews)
Nice room & friendly staff!

Reviewed on Jan 28, 2026

Hyatt Regency St. Louis at The Arch
See all 1,882 properties in University City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
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Kid Friendly Vacations

Discover the most popular places to visit in University City

Tivoli Theatre

4.5/5(4 reviews)

You can get tickets for a performance at Tivoli Theatre on your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Tivoli Theatre

St. Louis Walk of Fame

You can spend an afternoon studying the exhibits at St. Louis Walk of Fame in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

St. Louis Walk of Fame

Componere Gallery

You can spend an afternoon studying the exhibits at Componere Gallery during your travels in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Componere Gallery

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$32
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis Premium Driving Tour with Boat Ride & Arch

St. Louis Premium Driving Tour with Boat Ride & Arch

$174
per adult
100% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

$169
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.