University City Vacations from $495

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Your University City Vacation

Book an University City vacation package and experience the rhythm and vibe of this sought-after neighborhood. With all your travel plans worked out, the only thing you need to focus on here is having a good time. Eager to head out and see the sights during your trip to University City? Make sure you check out nearby attractions such as St. Louis Art Museum, Washington University in St. Louis and Saint Louis Galleria Mall. Expedia is here to put your plans into action. Book your ideal University City vacation today.

The Latest University City Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Motel 6 Troy, IL

Motel 6 Troy, IL

2 out of 5
Price was $602, price is now $495 per person
$495
per person
Apr 25 - May 2
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to St. Louis (STL)
7.6/10 Good! (525 reviews)
We chose this hotel because at 10 p.m. we were looking for someplace to sleep that was inexpensive. Leaving next morning. It was definitely minimalistic. Front desk man was polite. We could not find tv remote and he gave us another one. Still couldn’t get any audio out of tv. Bathtub was not as clean as should be. Towels were very thin. No amenities at all. Two tiny bars of soap for sink and bath. Bed was ok. King bed with 3 small pillows. Fairly clean otherwise. They had coffee in the a.m. Have to say for $30 more could’ve had a much better room close by.

Reviewed on Dec 30, 2025

The Principal Hotel

The Principal Hotel

3.5 out of 5
Price was $1,029, price is now $795 per person
$795
per person
Apr 25 - May 2
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to St. Louis (STL)
9.8/10 Exceptional! (175 reviews)
This was of the most cleanest and unique hotel! I loved the lockers painted as books! The detention Hall bar and metal small locker bed side table in the room. The bed is SUPER comfortable!! The restaurant - the graphite was phenomenal.. loved the creative menu to go with hotel. We will recommend this hotel to everyone!! Outstanding staff as well.. not mean none in hotel or restaurant! Thank you all!!

Reviewed on Mar 2, 2026

Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection

4 out of 5
Downtown St. Louis
Price was $828, price is now $672 per person
$672
per person
Apr 10 - Apr 12
found 1 day ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
8.8/10 Excellent! (458 reviews)
Great Luxury Hotel and location.

Reviewed on Mar 4, 2026

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

5 out of 5
Downtown St. Louis
Save 100% on your flight
Price was $2,428, price is now $2,010 per person
$2,010
per person
May 16 - May 23
found 15 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to St. Louis (STL)
9.4/10 Exceptional! (1,000 reviews)
Beautiful accommodations. Attentive and genuine staff. We felt like celebrities. Beyond first class service!!

Reviewed on Feb 23, 2026

Landing Apartments - Eureka

Landing Apartments - Eureka

4 out of 5
Price was $934, price is now $785 per person
$785
per person
Apr 30 - May 3
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to St. Louis (STL)
No reviews

Where to stay in University City

Find the best University City areas and neighborhoods for the activities you enjoy most. Learn more about University City
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

3 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

University City Hotel Deals

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $115 total per night from Mar 9 to Mar 10
$115 total
Mar 9 - Mar 10
Total with taxes and fees
8.8/10 Excellent! (1,866 reviews)
Clean room, friendly staff and close to attractions and concert venue (walking distance) Worked out great for our stay.

Reviewed on Mar 3, 2026

Pear Tree Inn St. Louis Near Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Apr 5 to Apr 6
$153 total
Apr 5 - Apr 6
Total with taxes and fees
9/10 Wonderful! (1,638 reviews)
The valet was so nice. She was the best empire

Reviewed on Mar 4, 2026

21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $122 total per night from Mar 29 to Mar 30
$122 total
Mar 29 - Mar 30
Total with taxes and fees
8.8/10 Excellent! (3,107 reviews)
I stayed here in 2025 and made sure to return when in town again. The rooms are great, the price is reasonable, and the free breakfast was outstanding. Also, the parking garage is priced reasonably and I saved a lot of money leaving my car at the hotel and taking the light rail downtown.

Reviewed on Mar 4, 2026

Clayton Plaza Hotel & Extended Stay
See all 1,902 properties in University City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in University City

St. Louis Walk of Fame

You can spend an afternoon studying the exhibits at St. Louis Walk of Fame in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

St. Louis Walk of Fame

Tivoli Theatre

4.5/5(4 reviews)

You can get tickets for a performance at Tivoli Theatre on your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Tivoli Theatre

Componere Gallery

You can spend an afternoon studying the exhibits at Componere Gallery during your travels in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Componere Gallery

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

$30
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
St. Louis Premium Driving Tour with Boat Ride & Arch

St. Louis Premium Driving Tour with Boat Ride & Arch

$174
per adult
100% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.