University City Vacations from $284

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Your University City Vacation

Book an University City vacation package and experience the rhythm and vibe of this sought-after neighborhood. With all your travel plans worked out, the only thing you need to focus on here is having a good time. Eager to head out and see the sights during your trip to University City? Make sure you check out nearby attractions such as St. Louis Art Museum, Washington University in St. Louis and Saint Louis Galleria Mall. Expedia is here to put your plans into action. Book your ideal University City vacation today.

The Latest University City Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

$284
per person
Sep 25 - Sep 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,676 reviews)
The front desk staff, housekeepers and Breakfast area were stellar.

Reviewed on Aug 24, 2026

Remodeled and Inviting Free EV

Remodeled and Inviting Free EV

Save 100% on your flight
$496
per person
Nov 2 - Nov 7
found 23 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
10/10 Exceptional! (1 review)
It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it

Reviewed on Aug 7, 2026

HoteLumiere at the Arch Hotel & Casino - A Caesars Rewards Destination

HoteLumiere at the Arch Hotel & Casino - A Caesars Rewards Destination

Downtown St. Louis
Save 100% on your flight
$394
per person
Sep 30 - Oct 5
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
6.8/10 (1,013 reviews)
The carpet needs replaced, the ceiling was dirty where the ac vent was, otherwise it was a nice room.The staff were very helpful,the casino was ausome and the parking was good

Reviewed on Aug 23, 2026

The Cheshire

The Cheshire

Save 100% on your flight
$321
per person
Sep 25 - Sep 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,006 reviews)
Alhonna Resort LLC

Alhonna Resort LLC

Save 100% on your flight
$793
per person
Sep 26 - Oct 3
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.8/10 Excellent! (335 reviews)
Location was wonderful Pool was refreshing We had an enjoyable overnight stay

Reviewed on Aug 17, 2026

Where to stay in University City

Find the best University City areas and neighborhoods for the activities you enjoy most. Learn more about University City
A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis

3 out of top 10 points of interest in this area

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis
The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Find hotels in Clayton
A street with parked cars, a building with a sign reading "Brennan's", and a tree in front.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Find hotels in Central West End
An ornate hall with arched ceilings and intricate patterns.

Downtown West

2 out of top 10 points of interest in this area

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Find hotels in Downtown West
A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Find hotels in Creve Coeur

University City Hotel Deals

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$134 nightly
$158 total
Aug 28 - Aug 29
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$93 nightly
$109 total
Sep 6 - Sep 7
Total with taxes and fees
8.8/10 Excellent! (3,375 reviews)
"Always clean, staff friendly, breakfast is good."

Reviewed on Aug 24, 2026

Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
$123 nightly
$144 total
Sep 1 - Sep 2
Total with taxes and fees
8.6/10 Excellent! (2,248 reviews)
"Good location to events nice shuttle worth the money room clean ."

Reviewed on Aug 23, 2026

Hollywood Casino & Hotel St. Louis
See all 2,003 properties in University City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular University City attractions

Center of Creative Arts

Enjoy an outing to Center of Creative Arts during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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St. Louis Walk of Fame

You can spend an afternoon studying the exhibits at St. Louis Walk of Fame in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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St. Louis Black Repertory Company

You can get tickets for a performance at St. Louis Black Repertory Company during your stay in St. Louis. Visit the shops in this family-friendly area, or simply enjoy its restaurants.
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Heman Park Tennis Center

Catch an event at Heman Park Tennis Center during your trip to St. Louis. Visit the shops in this family-friendly area, or simply enjoy its restaurants.
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Tivoli Theatre

9.0/10 (4 reviews)
You can get tickets for a performance at Tivoli Theatre on your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Componere Gallery

You can spend an afternoon studying the exhibits at Componere Gallery during your travels in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
The Gateway Arch National Park & Museum

StL's Signature "Sights and Bites" - Private Tour in St. Louis

$175
per adult
StL's Signature "Sights and Bites" - Private Tour in St. Louis
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

$25
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.