Title: Whetsell Vacation Packages 2026 from $549 | Expedia.com [Hotels in Whetsell](https://expedia.com/Whetsell-Hotels.d553248635974902828.Travel-Guide-Hotels)[Vacation Rentals in Whetsell](https://expedia.com/Whetsell-Vacation-Rentals.d553248635974902828.Travel-Guide-VacationRentals)[Car Rentals in Whetsell](https://expedia.com/Car-Rentals-In-Whetsell.d553248635974902828.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Whetsell Vacations from $549 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## The Latest Whetsell vacation packages Price found within the past 48 hours. Click for updated prices. ![The Francis Marion Hotel](https://images.trvl-media.com/lodging/1000000/50000/41300/41204/3ad3c4ea_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Francis Marion Hotel Charleston Historic District Save 100% on your flight $549 per person May 9 - May 12 found 1 day ago Roundtrip flight included Boston (BOS) to Charleston (CHS) 9/10 Wonderful! (1,942 reviews) Restaurants and shops very close Reviewed on Mar 2, 2026 ![The Ryder Hotel](https://images.trvl-media.com/lodging/1000000/10000/4600/4544/d4e1e925_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Ryder Hotel Charleston Historic District Save 100% on your flight $1,230 per person Apr 9 - Apr 12 found 1 day ago Roundtrip non-stop flight included Boston (BOS) to Charleston (CHS) 8.6/10 Excellent! (1,009 reviews) Love the outdoor fireplace and lounge areas. Reviewed on Mar 2, 2026 ![Folly Beach Getaway Near Sand Covered Lounge, BBQ & Outdoor TV Tidecrest by Avantstay](https://images.trvl-media.com/lodging/125000000/124160000/124151300/124151218/2cc90922_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Folly Beach Getaway Near Sand Covered Lounge, BBQ & Outdoor TV Tidecrest by Avantstay Save 100% on your flight $2,419 per person Apr 17 - Apr 22 found 1 day ago Roundtrip flight included Philadelphia (PHL) to Charleston (CHS) No reviews ![The Nicholas](https://images.trvl-media.com/lodging/109000000/108630000/108620900/108620832/cfdf2587_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Nicholas Downtown Charleston Save 100% on your flight $1,079 per person May 16 - May 19 found 1 day ago Roundtrip flight included Boston (BOS) to Charleston (CHS) 9.6/10 Exceptional! (30 reviews) Mattress firm to the extreme and not level. No on-site baggage storage. No on-site management (which meant management was not aware the smoke detectors were wired in and were being tested by a technician on on property rather than ringing due to batteries needing to be replaced). Not a true b&b in that there were only boxed meals to go. Reviewed on Dec 13, 2025 ![Sawyer by Avantstay Stunning Isle Of Palms Home w/ Pool!](https://images.trvl-media.com/lodging/84000000/83920000/83910700/83910604/cf297b36_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Sawyer by Avantstay Stunning Isle Of Palms Home w/ Pool! Save 100% on your flight $2,273 per person Apr 25 - Apr 29 found 14 hours ago Roundtrip non-stop flight included Boston (BOS) to Charleston (CHS) No reviews Don't see what you're looking for? See all available trips from Columbus to Whetsell [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-03/2026-04-10/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=null&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_553248635974902828) ## Whetsell Hotel Deals ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St. Santee SC Fully refundableReserve now, pay when you stay $112 nightly $124 total Mar 16 - Mar 17 Total with taxes and fees 9.2/10 Wonderful! (744 reviews) Great room Reviewed on Mar 1, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F16%2F2026&endDate=3%2F17%2F2026&selected=92600969&PinnedHotelID=92600969&HadPinnedHotel=true®ionId=553248635974902828) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Baymont by Wyndham Santee 249 Britain Street Santee SC Fully refundableReserve now, pay when you stay $80 nightly $89 total Mar 4 - Mar 5 Total with taxes and fees 8/10 Very Good! (1,432 reviews) Room was quiet and neat. Reviewed on Mar 2, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&selected=15379&PinnedHotelID=15379&HadPinnedHotel=true®ionId=553248635974902828) ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fairfield Inn & Suites by Marriott Santee 9074 Old Number Six Hwy Santee SC $125 nightly $139 total Mar 17 - Mar 18 Total with taxes and fees 9.8/10 Exceptional! (1,007 reviews) Clean comfortable stay. Breakfast was a nice plus. Reviewed on Feb 28, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F17%2F2026&endDate=3%2F18%2F2026&selected=26116&PinnedHotelID=26116&HadPinnedHotel=true®ionId=553248635974902828) [See all 210 properties in Whetsell](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F4%2F2026&endDate=3%2F5%2F2026®ionId=553248635974902828) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Whetsell Vacation Packages ## Whetsell Essential Information | Language | English | | ---------- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | U.S dollars | | Top Sights | [Santee National Golf Club](https://www.expedia.com/Santee-National-Golf-Club-Santee.d553248621532654897.Vacation-Attraction), [St. George United Methodist Church](https://www.expedia.com/St-George-United-Methodist-Church-St-George.d6266359.Vacation-Attraction) and [Santee Outlets](https://www.expedia.com/Santee-Outlets-Santee.d6140634.Vacation-Attraction) | ## More vacations you might like 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Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app