Santee Vacations from $489

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Your Santee Vacation

Enjoy unforgettable adventures when you book a vacation package to Santee. Whether you're a foodie, art buff or just a traveler who loves discovering new places, there's something for everyone in this lively city. If your trip to Santee includes some sightseeing, don't miss famous attractions like Santee State Park, Santee Cooper Country Club and Santee Outlets. Stop daydreaming and start traveling. Browse the many options on Expedia today and put your Santee vacation plans into action!

The Latest Santee vacation packages

Price found within the past 48 hours. Click for updated prices.
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
Seven Oaks
Price was $614, price is now $489 per person
$489
per person
Sep 6 - Sep 12
found 6 hours ago
Roundtrip non-stop flight included
Chicago (CHI) to Columbia (CAE)
8.2/10 Very Good! (1,111 reviews)
Decent place to stay and at a good rate! Would stay again

Reviewed on Jul 4, 2026

Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
Downtown Columbia
Price was $1,086, price is now $860 per person
$860
per person
Sep 6 - Sep 12
found 6 hours ago
Roundtrip flight included
Chicago (CHI) to Columbia (CAE)
8.8/10 Excellent! (1,010 reviews)
The rooms were great. Beds and pillows comfortable. Modern rooms

Reviewed on Jul 2, 2026

Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
Downtown Columbia
Price was $1,139, price is now $911 per person
$911
per person
Sep 6 - Sep 12
found 6 hours ago
Roundtrip flight included
Chicago (CHI) to Columbia (CAE)
9.4/10 Exceptional! (1,006 reviews)
We moved our stay. It was adorably decorated with Gamecock themes and very colorful. Our room was good size and the bed was very comfortable. Highly recommend

Reviewed on Jul 3, 2026

Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista

3.5 out of 5
Downtown Columbia
Price was $1,046, price is now $845 per person
$845
per person
Sep 6 - Sep 12
found 6 hours ago
Roundtrip flight included
Chicago (CHI) to Columbia (CAE)
9.4/10 Exceptional! (1,222 reviews)
Perfect location! Very clean and room had everything we needed!

Reviewed on Jul 2, 2026

SpringHill Suites by Marriott Columbia Downtown/The Vista

SpringHill Suites by Marriott Columbia Downtown/The Vista

3 out of 5
Downtown Columbia
Price was $881, price is now $731 per person
$731
per person
Sep 6 - Sep 12
found 6 hours ago
Roundtrip non-stop flight included
Chicago (CHI) to Columbia (CAE)
8.8/10 Excellent! (1,002 reviews)
Equivalent to a Super 8! I was so disappointed when we arrived thinking it was the quality of Marriott Springhill Suites. a. The toilet in the room was super low, like a child’s size toilet b. The small pocket sized lotion was half full as it it was used, or housekeeping didn’t bother to check c. The price was too much for the accommodations. d. The room had a stench in it. Typically we would ask for another room but we were too exhausted e. There was hair in the toilet. Overpriced for the accommodations

Reviewed on Jul 4, 2026

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Stay near popular Santee attractions

Santee State Park

8.0/10 (219 reviews)
Perched on Lake Marion's shores, Santee State Park offers unique rondette cabins built over water. Hike through cypress swamps and sinkholes while spotting alligators, fox squirrels, and diverse birdlife.
See properties

Santee Hotel Deals

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $87 total per night from Jul 7 to Jul 8
$87 total
Jul 7 - Jul 8
Total with taxes and fees
8/10 Very Good! (1,472 reviews)
"Air was noisy."

Reviewed on Jul 3, 2026

Baymont by Wyndham Santee
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Aug 2 to Aug 3
$109 total
Aug 2 - Aug 3
Total with taxes and fees
9.2/10 Wonderful! (871 reviews)
"Very good"

Reviewed on Jul 2, 2026

Tru By Hilton Santee
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

3 out of 5
9074 Old Number Six Hwy Santee SC
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $149 total per night from Jul 12 to Jul 13
$149 total
Jul 12 - Jul 13
Total with taxes and fees
9.8/10 Exceptional! (1,004 reviews)
"I love this hotel. Everyone is super helpful. We had a pretty big issue when we got there but the staff is extremely quick to help out and take responsibility when there is something wrong. Love this place, will definitely visit again."

Reviewed on Jul 3, 2026

Fairfield Inn & Suites by Marriott Santee
See all 312 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santee Vacation Packages

Santee Essential Information

Language
English
Currency
U.S dollars
Population
940
Max Temp Winter
55ºF
Max Temp Summer
90ºF
Top Sights
Santee State Park, Santee Cooper Country Club and Santee National Golf Club

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Frequently asked questions

How much does a Santee vacation package cost?
Offering excellent value package deals from $489 on Expedia, you'll be surprised at how little a vacation to Santee costs! Our packages make travel planning easier and your savings go further.
What are the cheapest months to go to Santee?
If you're hoping to snag a cheap Santee vacation package, consider visiting in January, September and October. You're likely to find better prices on accommodations and flights during these quieter months — ideal for budget-conscious travelers.
How many days is enough for Santee?
The ideal length for your Santee vacation depends on what you'd like to see and do. Usually, a few days to a week will give you time to hit all the leading attractions and explore some hidden treasures along the way.
Is it worth booking a vacation package to Santee?
It's no wonder a Santee vacation is on the to-do list of many travelers. Major attractions like Santee State Park are just the beginning of things to see and do here.
How to find the best Santee package deals?
Use Expedia's handy filters to help you find some fabulous Santee package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or search for Santee package deals in the low season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Santee vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking stays and flights individually. Better still, you can customize your Santee trip to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santee?
If you have your Santee vacation dates locked in, book as soon as you can to score some incredible deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Santee vacation packages?
If you're anything like us, you love discovering new places but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Santee trip across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up cheap vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.