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Compare 122 Vacation Homes in Wykoff with updated reviews, rates, and availability.

The Hen House Retreat - A Comfortable Place to Roost
9.6 out of 10, Exceptional, (70)
"This was my 3rd time at the Hen House, this time with my daughter. Love the beautiful location & the fun town of Lanesboro close by. Highly recommend to anyone wanting to unwind."
The price is $221
includes taxes & fees
$206 per night
Sep 22 - Sep 23
The Hen House Retreat - A Comfortable Place to Roost
Silver Lake Oasis
9.6 out of 10, Exceptional, (29)
"Stayed 3 nights for tests at Mayo. Good location. Quick drive to hospital. Nice two mile walk around Silver Lake. The house had everything we needed and was very comfy, except for the tv positioning. Hard to see from the couch. "
Silver Lake Oasis
St. Augustine Mint House GARAGE!!
10.0 out of 10, Exceptional, (59)
"This little house was just what my husband and I needed for our trip to Mayo. All the little homey touches that Denise has thought of made our anxiety ridden trip feel better. We’ll definitely look to stay at this property again. "
St. Augustine Mint House GARAGE!!
Park in the Garage and Walk to Mayo Clinic
10.0 out of 10, Exceptional, (49)
"Staying here was so easy, and comfy! Traffic was simple to get to Mayo. And the owner was so very helpful and plesant! "
Park in the Garage and Walk to Mayo Clinic
Garage!! St. Augustine Place Near Mayo!
10.0 out of 10, Exceptional, (78)
"Property is in a good location. We needed something close to Mayo Clinic. It had plenty of bedrooms for our group. "
The price is $280
includes taxes & fees
$243 per night
Sep 22 - Sep 23
Garage!! St. Augustine Place Near Mayo!
St. Augustine's Restful Heart House WALK to St. Mary's
10.0 out of 10, Exceptional, (38)
"The house was the perfect place while we had appointments at Mayo. It was very clean and stocked with all the essentials. The owner was very accessible by text when I had questions. It’s an easy walk to St. Mary’s where you can catch the shuttle to the other Mayo buildings."
The price is $330
includes taxes & fees
$287 per night
Sep 22 - Sep 23
St. Augustine's Restful Heart House WALK to St. Mary's
No Stairs, 2 mi to Mayo, Pet Friendly, 3 Bdrm, Fenced Yard
10.0 out of 10, Exceptional, (9)
"Another Bonus—2 full bathrooms. Never underestimate the convenience that presents when everyone is trying to get ready in the morning. We immensely enjoyed our 5 day stay here. The house was clean and spacious. The back yard was fenced for our dog. And overall, we felt safe in this neighborhood. We come every year to the Mayo Clinic, and this home was the best place we have ever stayed."
No Stairs, 2 mi to Mayo, Pet Friendly, 3 Bdrm, Fenced Yard
Century Cottage-PERFECT for Mayo & downtown visitors!
10.0 out of 10, Exceptional, (95)
"I cannot say enough about how great of a stay we had. Very accomodating. Everything as described. Highly recommend. We will be using again when back in town. "
Century Cottage-PERFECT for Mayo & downtown visitors!
"Walden Pond" Adventure Amidst 44 Private Acres
10.0 out of 10, Exceptional, (113)
"Stayed 3 weeks. It was wonderful. Especially liked the trails for hiking with our dog. It was close to Rochester and Stewartville had a nice grocery called Fareway. Also had a good place for pizza called 2 Brothers. My son liked the proximity to Anytime Fitness too."
"Walden Pond" Adventure Amidst 44 Private Acres
Cozy house / small town living. Attractions include trout capital of Minnesota
5.6 out of 10, (8)
"We came up for the weekend for our fanily reunion . The house is old & smells like an old house, which isn't a bad thing. The house was clean & tidy. We couldn't find the hot tub,but it was all good. We didn't spend much time at the house, except for sleeping & watching tv in the evening. Thank you for a pleasant stay."
The price is $204
includes taxes & fees
$190 per night
Oct 1 - Oct 2
Cozy house / small town living. Attractions include trout capital of Minnesota
Quaint Boutique Home *NEAR MAYO*
9.6 out of 10, Exceptional, (36)
"This is a great location to stay because it is convenient to Mayo, and also close to a lot of areas to get food And groceries."
Quaint Boutique Home *NEAR MAYO*
Delightful family home near pool, playground, park, nature center 1.6 mi to Mayo
10.0 out of 10, Exceptional, (14)
" “Beautiful house, fully equipped, clean, spacious, and comfortable, close to everything, just as described. The master bedroom has a king-size bed that can recline. The house is a 5-minute drive from the Mayo Clinic and a 30-minute walk. It’s also a 10-minute drive from St. Mary’s Hospital. Lovely surroundings with beautiful parks. Colette, the host, is super attentive, kind, and always ready to help if you need anything extra. It truly feels like a home away from home. I highly recommend it.”"
Delightful family home near pool, playground, park, nature center 1.6 mi to Mayo
2023 Construction, 5 BR, Gym, Game Area
10.0 out of 10, Exceptional, (13)
"We had the most wonderful stay at Pamela’s beautiful home! Everything was perfect from check in to check out. Our whole family agreed this was one of the best, if not the best vacation rentals we’ve had the pleasure to stay in. Pamela was so helpful and accommodating with any questions we had. Look forward to returning the next time we’re in Rochester. "
2023 Construction, 5 BR, Gym, Game Area
Entire Boutique Home Kutzky Park ★ Walk to Mayo ★
10.0 out of 10, Exceptional, (10)
"We needed a place to stay while getting my father to appointments at Mayo Clinic. This was a beautiful, comfortable, quiet house close by. Communication with owners was easy and we didn’t have any issues with the property. The house is darling and has been updated beautifully. Thanks for a great experience!"
Entire Boutique Home Kutzky Park ★ Walk to Mayo ★
Private Cozy Apartment *NEAR MAYO*
9.8 out of 10, Exceptional, (44)
"Exactly what we needed, small but cozy. Loved sitting in the back yard and on the private porch perched up high!"
The price is $120
includes taxes & fees
$104 per night
Sep 30 - Oct 1
Private Cozy Apartment *NEAR MAYO*
St. Augustine at The Mayo, Gonda, St. Marys WALK! Fenced yard! Great Location!
10.0 out of 10, Exceptional, (39)
"We stayed in this home for a sporting event in Rochester for our children. The home gave us space to rest, cook meals and recharge after very early mornings and late evenings of sports."
The price is $295
includes taxes & fees
$256 per night
Oct 9 - Oct 10
St. Augustine at The Mayo, Gonda, St. Marys WALK! Fenced yard! Great Location!
Recliners. Single Level Living. Walk in shower.
10.0 out of 10, Exceptional, (10)
"My wife and I stayed at this property during a visit to Mayo Clinic. It is exactly as advertised! It was very clean and everything you could possibly need is there. We will definitely stay at this property for any future visits."
Recliners. Single Level Living. Walk in shower.
Lots of charm and only blocks away from the Root River and Bike trails
9.8 out of 10, Exceptional, (9)
"House was clean and very charming. Worked out well for our stay in Preston to visit family "
Lots of charm and only blocks away from the Root River and Bike trails
Civic Center, River Front, WALK to Mayo Clinic!! GARAGE Parking!
9.8 out of 10, Exceptional, (91)
"Another excellent experience with a host I trust to make my visits to Mayo Clinic less stressful!"
The price is $200
includes taxes & fees
$174 per night
Sep 25 - Sep 26
Civic Center, River Front, WALK to Mayo Clinic!! GARAGE Parking!
Walking distance of all amenities of Lanesboro! Bike the trail~ float the river
10.0 out of 10, Exceptional, (9)
"Our group of six adults thoroughly enjoyed our stay at Jill and Jim's home. They thought of everything you would possibly need, especially in the large kitchen. The house was immaculate and the beds were comfortable. We loved being so close to downtown and the trails. The lounging spaces inside and out are very comfortable. It is fun to see Lanesboro continue to thrive. Kayaking down the Root was a bit challenging at times with the water exposing so many boulders, but tons of fun. Do not...
Walking distance of all amenities of Lanesboro! Bike the trail~ float the river
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Other property types in Wykoff

The Berkman
3.0 star property
9.6 out of 10, Exceptional, (246)
"The Berkman Hotel is my other home. So, comfortable!!"
The price is $208
includes taxes & fees
$181 per night
Sep 25 - Sep 26
The Berkman
Heritage hideaway-Secluded Log Cabin
10.0 out of 10, Exceptional, (348)
"Had a lovely stay at the Hideaway…cute and cozy and peaceful setting on top of a bluff! Would love to stay again! "
Heritage hideaway-Secluded Log Cabin
Valley Cabin
9.0 out of 10, Wonderful, (6)
"This is a great property. Peaceful, surrounded by fields & forests, birds singing, and fresh air. Wonderful parks and trails near by. Dan was a great host. I want to come back and stay in the fall and winter. This would also be a great place for a family get away"
The price is $133
includes taxes & fees
$124 per night
Sep 30 - Oct 1
Valley Cabin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.