Zona 21 Vacations from $898

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Your Zona 21 Vacation

Planning your next adventure just got easier with a vacation package to Zona 21. Embrace the best this neighborhood has to offer while creating fond memories that will last forever. When the time comes to go see the sights, your trip to Zona 21 should include a visit to Mundo Petapa and Universidad del San Carlos de Guatemala. Stop daydreaming and start doing. When it's time to book your vacation to Zona 21, Expedia will help get you there.

The Latest Zona 21 Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Villas La Mar

$898

per person

Sep 18 - Sep 21

found 1 day ago

Roundtrip non-stop flight included

New York (NYC) to Guatemala City (GUA)

8.2/10 Very Good! (147 reviews)

Nice place

Reviewed on Jul 8, 2026

Hotel Soleil La Antigua

$1,054

per person

Sep 22 - Sep 29

found 19 hours ago

Roundtrip non-stop flight included

Atlanta (ATL) to Guatemala City (GUA)

8.6/10 Excellent! (1,002 reviews)

Casa Faustina Boutique Hotel

Save 100% on your flight

$1,106

per person

Sep 10 - Sep 17

found 14 hours ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Guatemala City (GUA)

8.8/10 Excellent! (125 reviews)

Excellent staff and beautiful hotel. I would love to stay here again

Reviewed on Jul 28, 2026

Kula Maya Boutique Hotel & Spa

$1,262

per person

Oct 25 - Nov 1

found 1 day ago

Roundtrip non-stop flight included

New York (JFK) to Guatemala City (GUA)

9.4/10 Exceptional! (167 reviews)

El Carmen Hotel

Historic Center

$1,147

per person

Sep 22 - Sep 29

found 19 hours ago

Roundtrip non-stop flight included

Atlanta (ATL) to Guatemala City (GUA)

9/10 Wonderful! (860 reviews)

Where to stay in Zona 21

Find the best Zona 21 areas and neighborhoods for the activities you enjoy most. Learn more about Zona 21

A monument with a circular base and a central column, surrounded by a landscaped garden with trimmed hedges and trees.

Zona 10

3 out of top 10 points of interest in this area

Zona 10 is known for its ample dining options, and you can make a stop by Oakland Mall and Plaza Fontabella Shopping Center while in the area.

A cityscape with a prominent modern building, a plaza with people, and surrounding urban structures.

Zona 13

1 out of top 10 points of interest in this area

Zona 13 is noteworthy for its gardens, and you can make a stop at top attractions like Avenida Las Américas and La Aurora Zoo.

A park with a monument, manicured hedges, and hydrangea bushes.

Zona 1

Zona 1 is noteworthy for its historic sites, and you can make a stop at top attractions like Guatemala City Hall and Central Market.

Zona 9

1 out of top 10 points of interest in this area

Zona 9 is known for its abundant dining options, and you can plan a trip to Avenida La Reforma and Torre del Reformador while you're in town.

Zona 4

Visitors to Zona 4 enjoy its restaurants, and if you want to do some exploring, Avenida La Reforma is worth a stop.

Zona 21 Hotel Deals

Barceló Guatemala City

7 Avenida 15-45, Zona 9 Guatemala City Guatemala

Fully refundableReserve now, pay when you stay

$89 nightly

$108 total

Aug 22 - Aug 23

Total with taxes and fees

Hotel Museo Spa Casa Santo Domingo

3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez

Fully refundableReserve now, pay when you stay

$257 nightly

$313 total

Aug 12 - Aug 13

Total with taxes and fees

Tikal Futura Hotel & Convention Center

Calzada Roosevelt 22-43 Guatemala City Guatemala

Fully refundableReserve now, pay when you stay

$110 nightly

$134 total

Aug 16 - Aug 17

Total with taxes and fees

See all 1,268 properties in Zona 21

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.