Title: The Best 5 Star Hotels in Seffner, FL from $167 | Expedia.com [Seffner Travel Guide](https://expedia.com/Seffner.dx183120)[Hotels in Seffner](https://expedia.com/Seffner-Hotels.d183120.Travel-Guide-Hotels)[Vacation Rentals in Seffner](https://expedia.com/Seffner-Vacation-Rentals.d183120.Travel-Guide-VacationRentals)[Flights to Seffner](https://expedia.com/Cheap-Flights-To-Seffner.d183120.Travel-Guide-Flights)[Car Rentals in Seffner](https://expedia.com/Car-Rentals-In-Seffner.d183120.Car-Rental-Guide)[Seffner Vacation Packages](https://expedia.com/Seffner.d183120.Destination-Travel-Guides) ![Winter Landscape of Hillsborough river at Lettuce lake park ](https://images.trvl-media.com/place/183120/e43892f8-b506-41d3-bf33-6db9a2c3f004.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/183120/e43892f8-b506-41d3-bf33-6db9a2c3f004.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check availability on Seffner 5 Star Hotels Tonight [Mar 11 - Mar 12](https://www.expedia.com/Hotel-Search?regionId=183120&startDate=2026-03-11&endDate=2026-03-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 12 - Mar 13](https://www.expedia.com/Hotel-Search?regionId=183120&startDate=2026-03-12&endDate=2026-03-13&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=183120&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=183120&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Seffner 5-star hotels ![Lobby](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/7b52caf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/3fbaba62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/cbddc2cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/8d2fa88d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Tampa EDITION [](https://www.expedia.com/Tampa-Hotels-The-Tampa-Downtown-EDITION.h83980287.Hotel-Information) Downtown Tampa 9.4/10 Exceptional (349 reviews) "Clean room, staff was very courteous " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Grant $421 nightly $478 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Tampa-Hotels-The-Tampa-Downtown-EDITION.h83980287.Hotel-Information) ![The Adaline #6 - 2nd Floor Suite | Dining room](https://images.trvl-media.com/lodging/97000000/96050000/96044100/96044015/2cb71c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Adaline #7 - Second Floor Suite | Premium bedding, down comforters, Tempur-Pedic beds](https://images.trvl-media.com/lodging/97000000/96050000/96044100/96044015/f4efda1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Adaline #8 - 2nd Floor Suite | View from room](https://images.trvl-media.com/lodging/97000000/96050000/96044100/96044015/1874e093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Adaline #8 - 2nd Floor Suite | Living area | Smart TV, Netflix, Hulu, books](https://images.trvl-media.com/lodging/97000000/96050000/96044100/96044015/1f4974e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Adaline [](https://www.expedia.com/Tampa-Hotels-The-Adaline.h96044015.Hotel-Information) Hyde Park 9.6/10 Exceptional (65 reviews) "Really a great place. Everything was perfect." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $403 nightly $457 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Tampa-Hotels-The-Adaline.h96044015.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Seffner-Hotels.s50-0-d183120.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Seffner-Hotels.s50-0-d183120.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Seffner. ![The Westin Tampa Bay](https://images.trvl-media.com/lodging/1000000/10000/1600/1557/5e6ee943_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Westin Tampa Bay 7627 W Courtney Campbell Cswy Tampa FL $178 nightly $202 total Apr 5 - Apr 6 Total with taxes and fees 8.4/10 Very Good! (1,153 reviews) [](https://expedia.com/Tampa-Hotels-Westin-Tampa-Bay-Hotel.h1557.Hotel-Information) ![Hilton Tampa Airport Westshore](https://images.trvl-media.com/lodging/1000000/10000/5900/5870/88efd441_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Tampa Airport Westshore 2225 N Lois Ave Tampa FL $147 nightly $167 total Apr 5 - Apr 6 Total with taxes and fees 8.6/10 Excellent! (1,220 reviews) [](https://expedia.com/Tampa-Hotels-Hilton-Tampa-Airport-Westshore.h5870.Hotel-Information) ![Seminole Hard Rock Hotel & Casino Tampa](https://images.trvl-media.com/lodging/2000000/1050000/1044200/1044188/6efee43c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Seminole Hard Rock Hotel & Casino Tampa 5223 N Orient Road Tampa FL $374 nightly $425 total Apr 5 - Apr 6 Total with taxes and fees 8.8/10 Excellent! (1,329 reviews) [](https://expedia.com/Tampa-Hotels-Seminole-Hard-Rock-Hotel-Casino-Tampa.h1044188.Hotel-Information) Still don't see what you're looking for? [See all properties in Seffner.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F12%2F2026&endDate=3%2F13%2F2026®ionId=183120&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F12%2F2026&endDate=3%2F13%2F2026®ionId=183120&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F12%2F2026&endDate=3%2F13%2F2026®ionId=183120&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F12%2F2026&endDate=3%2F13%2F2026®ionId=183120&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F12%2F2026&endDate=3%2F13%2F2026®ionId=183120&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F12%2F2026&endDate=3%2F13%2F2026®ionId=183120&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Seffner Dinosaur World's life-sized prehistoric creatures make for fantastic family photos among lush Florida vegetation. Explore the serene trails of Hillsborough River State Park nearby, where rangers know which paths offer the best wildlife viewing. [See all hotels in Seffner](https://www.expedia.com/Hotel-Search?startDate=2026-03-25&endDate=2026-03-26&adults=2®ionId=183120) ![Winter Landscape of Hillsborough river at Lettuce lake park ](https://images.trvl-media.com/place/183120/e43892f8-b506-41d3-bf33-6db9a2c3f004.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Seffner Hotel Reviews ## Find out more about Seffner Pamper your every whim on your upcoming sabbatical. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Seffner so popular in the last year. There's no reason to delay a getaway to Seffner any longer. We should also mention, the hotels in this area receive outstanding marks for customer service, so you know you'll be well cared for during your getaway. Our 5-star hotels in Seffner are the perfect places to relax in when you really need to escape. You deserve the great vacation you're dreaming about. ### Get a Great Deal on 5-Star Hotels in Seffner Don't be afraid to request the best service from your hotel, along with the best conditions. Excellent customer care, spacious rooms, and rejuvenating spa offerings are all on offer. You're sure to find exactly the accommodation you need. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What creature comforts do you want in your lodging? A Swedish massage to help your cares fall away? A concierge to help you suggest the next attraction to visit? Fluffy down pillows, piping hot coffees, and even spectacular views...these hotels have it all. Want to see for yourself? Then check out the many reviews left by previous guests -- you can take their word for it! You won't sleep and order room service the entire time, though. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Seffner are the perfect place to rest up after a busy day. ### Your Getaway Starts Today The results are in, and Seffner 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Select one of the 5-star hotels in Seffner today and relax in the lap of luxury tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Seffner? > - Search for the lowest price per night from $167 ### What makes a hotel 5 stars in Seffner? ### Are there any 5-star all-inclusive resorts in Seffner? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Tampa Hotels ](https://www.expedia.com/Tampa-Hotels.d602996.Travel-Guide-Hotels) - [Hotels near Seffner Community Alliance ](https://www.expedia.com/Seffner-Community-Alliance-Tampa-Hotels.0-n553248635976473405-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Mango ](https://www.expedia.com/5Star-Mango-Hotels.s50-0-d3000345294.Travel-Guide-Filter-Hotels) - [Hotels near McCormick's Waterski Wakeboard and Cable Park ](https://www.expedia.com/McCormicks-Waterski-Wakeboard-And-Cable-Park-Hotels.0-l553248621532652761-0.Travel-Guide-Filter-Hotels) - [Mango Hotels ](https://www.expedia.com/Mango-Hotels.d3000345294.Travel-Guide-Hotels) - 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