Cherokee Vacation Rentals

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Our top choices for Cherokee vacation rentals

9.8 out of 10, Exceptional, (72)
"Clean, quaint cabin. "
United States
Nickole M.
$123 nightly
The price is $137
Jan 18 - Jan 19, 2026
Total with taxes and fees
⚡️Unique Cabin Studio, in ❤️ of Tri Cities

Apartment in Hampton

Lou's Loft of Hampton, TN
9.8 out of 10, Exceptional, (68)
"The place was perfect and cozy!"
United States
Rizwaan A.
$137 nightly
The price is $154
Jan 4 - Jan 5, 2026
Total with taxes and fees
Lou's Loft of Hampton, TN
9.8 out of 10, Exceptional, (79)
"Great place"
United States
Ronald E.
$145 nightly
The price is $163
Jan 5 - Jan 6, 2026
Total with taxes and fees
Peacocks, blacksmithing, buffalo, wildlife, a studio cabin by the pond.
10.0 out of 10, Exceptional, (103)
"Perfect overnight stay. Cabin was exactly as described and shown in pictures. Host was very accessible . "
United States
ELAINE N.
$123 nightly
The price is $137
Jan 4 - Jan 5, 2026
Total with taxes and fees
⚡️ Relaxing Cabin studio, in ❤️ of the Tri Cities.
10.0 out of 10, Exceptional, (2)
"We needed a place to stay that we could bring our small dog, and this place was perfect. Had a small yard for us to walk him in. We were gone during the day, home for lunch & at night. The room is about the size of a hotel room, and we were all comfortable there."
United States
Beverly G.
$151 nightly
The price is $174
Jan 20 - Jan 21, 2026
Total with taxes and fees
NEW 1BR efficiency apartment in Johnson City
10.0 out of 10, Exceptional, (14)
"We really enjoyed our stay!! We will definitely be back!!!"
United States
Renee B.
$160 nightly
The price is $179
Jan 19 - Jan 20, 2026
Total with taxes and fees
Bungalow /Hot tub /ping pong /Putt putt /corn hole /Jenga /connect 4/Checkers
9.8 out of 10, Exceptional, (6)
"Great location"
United States
Lee Ann F.
$158 nightly
The price is $182
Jan 28 - Jan 29, 2026
Total with taxes and fees
Modern Clean Interior. Near ETSU & JC Med Center
10.0 out of 10, Exceptional, (7)
"Nice place. Beds were comfortable. Good location. "
United States
Cary
$254 nightly
The price is $294
Jan 5 - Jan 6, 2026
Total with taxes and fees
3BR Home Near Historic Downtown Jonesborough
2.0 star property
10.0 out of 10, Exceptional, (14)
"Great location and space, right in the heart of JC. Would recommend! "
United States
Brett M.
$188 nightly
The price is $217
Jan 5 - Jan 6, 2026
Total with taxes and fees
Stay in heart of Johnson City - Urban Loft

Vacation Home in Johnson City

Restful on Rhody
9.6 out of 10, Exceptional, (20)
"Cozy and Cute! "
United States
angela
$145 nightly
The price is $162
Jan 5 - Jan 6, 2026
Total with taxes and fees
Restful on Rhody

Apartment in Johnson City

Sanctuary Co Pet-Friendly Apt
10.0 out of 10, Exceptional, (10)
"The property was clean, cute and cozy. It was exactly what we needed. The location was perfect for enjoying Johnson City. Would definitely stay there again. "
United States
Mary Jane L.
$147 nightly
The price is $168
Jan 4 - Jan 5, 2026
Total with taxes and fees
Sanctuary Co Pet-Friendly Apt

Apartment in Johnson City

3BR 2.5BA condo near downtown JC
10.0 out of 10, Exceptional, (1)
"We had a great time! Very easy check in - so clean with nice touches with the kitchen and bathroom soaps! The set up was perfect for us while we were in town for a wedding!"
United States
Jamie H.
$246 nightly
The price is $285
Jan 5 - Jan 6, 2026
Total with taxes and fees
3BR 2.5BA condo near downtown JC
9.0 out of 10, Wonderful, (6)
"Great place to stay! Thank you."
United States
Andrew P.
$187 nightly
The price is $217
Jan 6 - Jan 7, 2026
Total with taxes and fees
New construction 2nd level apartment -Downtown JC
9.4 out of 10, Exceptional, (21)
"Great price, great rental, and great location. "
United States
Jason D.
$151 nightly
The price is $173
Jan 1 - Jan 2, 2026
Total with taxes and fees
Sanctuary Co Loft in Downtown Johnson City
9.4 out of 10, Exceptional, (24)
"This was a great stay. Bed was very comfortable and home was clean and well stocked. Location was walkable to everything! Would definitely stay here again. "
United States
Marlee M.
$142 nightly
The price is $162
Jan 4 - Jan 5, 2026
Total with taxes and fees
Sanctuary Co Loft in Downtown Johnson City
10.0 out of 10, Exceptional, (2)
"The location was pleasant and clean. "
United States
April P.
$134 nightly
The price is $154
Jan 1 - Jan 2, 2026
Total with taxes and fees
Welcoming cottage close to ETSU, Medical Center and Downtown Johnson CityTN

Vacation Home in Johnson City

2BR, 1BA Remodeled House in Gray Community
9.6 out of 10, Exceptional, (9)
"Great location beautiful home wonderful stay "
United States
Robin H.
$227 nightly
The price is $255
Jan 5 - Jan 6, 2026
Total with taxes and fees
2BR, 1BA Remodeled House in Gray Community
9.0 out of 10, Wonderful, (10)
"The house is very nice and in a great location! It’s right across the street from Bristol Motor Speedway. We were there for a race at the drag strip so the location worked well for us. It’s also not far from downtown Bristol, it’s close to other stores and restaurants. The house is very nice with comfortable beds. There are plenty of blankets and towels. We would definitely stay there again! "
United States
Lauren G.
$288 nightly
The price is $312
Jan 4 - Jan 5, 2026
Total with taxes and fees
Dragster Dream House - Game Room - Walk to BMS
9.0 out of 10, Wonderful, (8)
"My wife and I stayed here for 6 weeks while I home was under construction to fix damages sustained from Hurricane Helene. The home was exactly what we needed! Super clean, stocked well, and great response time from management. "
United States
Joshua R.
$228 nightly
The price is $264
Jan 5 - Jan 6, 2026
Total with taxes and fees
3BR house in neighborhood with ETSU, JCMC, VA

Vacation Home in Elizabethton

The Cottage on Cottage
2.0 star property
10.0 out of 10, Exceptional, (1)
"Home was very comfortable and clean!The decor was great!!Check in was easy.Would definitely book again "
United States
Fran M.
$288 nightly
The price is $336
Jan 1 - Jan 2, 2026
Total with taxes and fees
The Cottage on Cottage
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cherokee Hotel Reviews

Find out more about Cherokee

Everything you need to know about Cherokee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Cherokee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Cherokee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Cherokee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Cherokee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Cherokee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $137 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Cherokee rentals

At Expedia, we put the best Cherokee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Cherokee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Cherokee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Cherokee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Cherokee?

Yes, we have vacation rentals near top points of interest in Cherokee, or you can go with a more remote option if you want a relaxing place to stay.

What are some of the best vacation home rentals that Cherokee has to offer?

Mountains surround Doe River 400 ft Frontage, wildlife out the back door. : This vacation home rental outside of Cherokee is located on the waterfront and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a private yard.

What can I see and do in Cherokee?

Explore the area and family-friendly sights such as Gray Fossil Museum, or get out into nature at a spot like Buffalo Mountain Park. In the larger area, you’ll find East Tennessee State University and Austin Springs Spa & Salon.

What’s a vacation rental in Cherokee like?

Vacation rentals are private properties you can reserve for several days or longer in Cherokee. Vacation rentals feature extras like laundry facilities and kitchens so you'll have all the conveniences of home. If you're concerned about a clean environment, a vacation rental can provide a sense of privacy away from public hotel elevators and lobbies packed with people while still allowing you to travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.