Title: Defiance Vacation Rentals from $212: Search Short-Term Rentals | Expedia.com

[Defiance Travel Guide](https://expedia.com/Defiance.dx6353634)[Hotels in Defiance](https://expedia.com/Defiance-Hotels.d6353634.Travel-Guide-Hotels)[Flights to Defiance](https://expedia.com/Cheap-Flights-To-Defiance.d6353634.Travel-Guide-Flights)[Car Rentals in Defiance](https://expedia.com/Car-Rentals-In-Defiance.d6353634.Car-Rental-Guide)[Defiance Vacation Packages](https://expedia.com/Defiance.d6353634.Destination-Travel-Guides)

![A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6353634&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=6353634&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=6353634&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=6353634&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Defiance vacation rentals

![Exterior](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/w905h683x60y0-7da69c98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/w507h683x260y0-03493f60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/ca1dea43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/f45a4107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Union

[](https://www.expedia.com/Union-Hotels-TJs-Country-Getaway.h71507563.Hotel-Information)

10/10

Exceptional

(46 reviews)

"Wonderful property, clean and very quiet!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lindsay J.

$144 nightly

$153 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Union-Hotels-TJs-Country-Getaway.h71507563.Hotel-Information)

![TV, fireplace](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/w2033h1365x15y0-e5f03757.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/943c3aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/adda266d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/bc9c69f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in Augusta

[](https://www.expedia.com/Augusta-Hotels-The-Marigold-Cottage-By-StayLage.h110319519.Hotel-Information)

8.4/10

Very Good

(9 reviews)

"We loved the cottage and the town of Augusta. Would definitely stay here again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tyler S.

$317 nightly

$353 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Augusta-Hotels-The-Marigold-Cottage-By-StayLage.h110319519.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/5d45ed4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/c61d9c27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/7d7d40ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/46f64c9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in Augusta

[](https://www.expedia.com/Augusta-Hotels-Adorable-Augusta-Cabin.h110062608.Hotel-Information)

8.6/10

Excellent

(13 reviews)

"Absolutely beautiful area. Cabin is so cozy"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aaron

$190 nightly

$212 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Augusta-Hotels-Adorable-Augusta-Cabin.h110062608.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/45000000/44130000/44124700/44124669/d4de2daa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/45000000/44130000/44124700/44124669/0aa09261.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/45000000/44130000/44124700/44124669/03086e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/45000000/44130000/44124700/44124669/216e0674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Pacific

[](https://www.expedia.com/Pacific-Hotels-Pet-And-Kid-Friendly-Duplex-With-2-Bedrooms.h44124669.Hotel-Information)

9.6/10

Exceptional

(47 reviews)

"Such a wonderful weekend. We had everything we needed. Lovely spot! Thank you"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveler

$158 nightly

$177 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Pacific-Hotels-Pet-And-Kid-Friendly-Duplex-With-2-Bedrooms.h44124669.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/1e8558f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/f3578af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/a7d9ee80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/b7b6310c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in Augusta

[](https://www.expedia.com/Augusta-Hotels-Rustic-Augusta-Cabin-By-StayLage.h110062605.Hotel-Information)

9.2/10

Wonderful

(5 reviews)

"I booked this place wit spend some homely time with my kids and it was amazing, the place was clean they even dropped off some extra towels without us having to ask, it was truly amazing. Will definitely stay there again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

teresa s.

$287 nightly

$320 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Augusta-Hotels-Rustic-Augusta-Cabin-By-StayLage.h110062605.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/70000000/69430000/69423500/69423401/005f7815.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/70000000/69430000/69423500/69423401/3b7191a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/70000000/69430000/69423500/69423401/79d15820.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/70000000/69430000/69423500/69423401/28cff9a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in Marthasville

[](https://www.expedia.com/Washington-Hotels-Cottage-Cabin.h69423401.Hotel-Information)

10/10

Exceptional

(219 reviews)

"This was a great getaway. Hosts were so nice and their dog was sweet! My little dog and I had a great stay. Thabk you!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tiffany P.

$161 nightly

$171 total

Mar 10 - Mar 11

Total with taxes and fees

[](https://www.expedia.com/Washington-Hotels-Cottage-Cabin.h69423401.Hotel-Information)

![5 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34110000/34101200/34101145/270-eee042bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/35000000/34110000/34101200/34101145/a076052e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![5 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34110000/34101200/34101145/c17ba958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, soap](https://images.trvl-media.com/lodging/35000000/34110000/34101200/34101145/c90a58e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa in Eureka

[](https://www.expedia.com/St-Louis-Hotels-Large-Villa-Ste-A.h34101145.Hotel-Information)

9.2/10

Wonderful

(46 reviews)

"Perfect for large group near 6 flags"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

sean p.

$389 nightly

$421 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Large-Villa-Ste-A.h34101145.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/35000000/34820000/34814500/34814455/24b502b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/35000000/34820000/34814500/34814455/5b625011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/35000000/34820000/34814500/34814455/a62878f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children's area](https://images.trvl-media.com/lodging/35000000/34820000/34814500/34814455/5c3f47e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Condo in Innsbrook

[](https://www.expedia.com/Wright-City-Hotels-Aspen-Heights-By-Innsbrook-Vacations.h34814455.Hotel-Information)

9.0/10

Wonderful

(10 reviews)

"Nice, quiet, relaxing place to stay! Great communication with the host. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lorna M.

$212 nightly

$218 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Wright-City-Hotels-Aspen-Heights-By-Innsbrook-Vacations.h34814455.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/105000000/104480000/104472500/104472401/d26497ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children's area](https://images.trvl-media.com/lodging/105000000/104480000/104472500/104472401/48c79dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/105000000/104480000/104472500/104472401/w1354h894x2y0-ad017ad0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/105000000/104480000/104472500/104472401/7ab85c58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Condo in Wright City

[](https://www.expedia.com/Wright-City-Hotels-Bright-Studio-Condo-On-The-Water.h104472401.Hotel-Information)

9.8/10

Exceptional

(45 reviews)

"It was very peaceful and close to all the activities we wanted to do like kayak fish and enjoy dinner looking out at the golf course. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mollie L.

$165 nightly

$177 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Wright-City-Hotels-Bright-Studio-Condo-On-The-Water.h104472401.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/36000000/35360000/35356300/35356213/65013358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/36000000/35360000/35356300/35356213/dfcff278.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/36000000/35360000/35356300/35356213/3677b840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/36000000/35360000/35356300/35356213/28ca12bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Condo in Wright City

[](https://www.expedia.com/Wright-City-Hotels-Lake-Aspen-Hideaway-By-Innsbrook-Vacations.h35356213.Hotel-Information)

9.8/10

Exceptional

(21 reviews)

"Check-in was easy and property was clean. Great place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Casey A.

$212 nightly

$218 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Wright-City-Hotels-Lake-Aspen-Hideaway-By-Innsbrook-Vacations.h35356213.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/49000000/48890000/48889400/48889316/b2d91e07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children's area](https://images.trvl-media.com/lodging/49000000/48890000/48889400/48889316/747ec0b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/49000000/48890000/48889400/48889316/283ba020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/49000000/48890000/48889400/48889316/59387c93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Condo in Innsbrook

[](https://www.expedia.com/Wright-City-Hotels-Lake-Aspen-Overlook-By-Innsbrook-Vacations.h48889316.Hotel-Information)

9.8/10

Exceptional

(23 reviews)

"Everything was extremely clean. We couldn’t have asked for a more quiet and relaxing stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brian L.

$212 nightly

$218 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Wright-City-Hotels-Lake-Aspen-Overlook-By-Innsbrook-Vacations.h48889316.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/49000000/49000000/48998600/48998582/b0517ecf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/49000000/49000000/48998600/48998582/ffbd1307.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/49000000/49000000/48998600/48998582/f143485f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/49000000/49000000/48998600/48998582/44f61ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Condo in Innsbrook

[](https://www.expedia.com/Wright-City-Hotels-Aspen-Sights-By-Innsbrook-Vacations.h48998582.Hotel-Information)

9.6/10

Exceptional

(13 reviews)

"Lovely weekend- enjoyed checking out Innsbrook"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Denise L.

$212 nightly

$218 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Wright-City-Hotels-Aspen-Sights-By-Innsbrook-Vacations.h48998582.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/35000000/34820000/34819100/34819094/8b377879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children's area](https://images.trvl-media.com/lodging/35000000/34820000/34819100/34819094/277efee2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/35000000/34820000/34819100/34819094/46c3d248.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/35000000/34820000/34819100/34819094/5361911e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Condo in Innsbrook

[](https://www.expedia.com/Wright-City-Hotels-Serene-Seebach-Sights-By-Innsbrook-Vacations.h34819094.Hotel-Information)

9.4/10

Exceptional

(10 reviews)

"Great clubhouse, plenty of wildlife roaming grounds, and friendly atmosphere."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

tony

$212 nightly

$218 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Wright-City-Hotels-Serene-Seebach-Sights-By-Innsbrook-Vacations.h34819094.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/35000000/34820000/34819200/34819110/987de7bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/35000000/34820000/34819200/34819110/51dd894a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/35000000/34820000/34819200/34819110/d5079940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children's area](https://images.trvl-media.com/lodging/35000000/34820000/34819200/34819110/21b63566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Condo in Innsbrook

[](https://www.expedia.com/Wright-City-Hotels-The-Harris-Overlook-By-Innsbrook-Vacations.h34819110.Hotel-Information)

9.4/10

Exceptional

(21 reviews)

"Great location and property within close distance of all Innsbrook has to offer. Would stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kristina U.

$212 nightly

$218 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Wright-City-Hotels-The-Harris-Overlook-By-Innsbrook-Vacations.h34819110.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335731/8dcec7f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335731/413f9d12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335731/c8cfaaff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House, Multiple Beds, Patio, City View | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335731/daecc64b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Washington

[](https://www.expedia.com/Washington-Hotels-Stylish-Home-Near-Wine-Country-JZ-Vacation-Rentals.h99335731.Hotel-Information)

8.0/10

Very Good

(1 review)

"Great communication, had a couple of leaks and shower flooded but the maintenance came right away to fix it. Overall clean, AC/Heat unit in each room, big kitchen, wonderful sitting area and decor."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stacy

$446 nightly

$508 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Washington-Hotels-Stylish-Home-Near-Wine-Country-JZ-Vacation-Rentals.h99335731.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/101000000/100820000/100818500/100818493/949c8c61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/101000000/100820000/100818500/100818493/757836ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100820000/100818500/100818493/d72dc64d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100820000/100818500/100818493/8b64b0ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in O'Fallon

[](https://www.expedia.com/St-Louis-Hotels-The-Cozy-Family-Retreat.h100818493.Hotel-Information)

8.4/10

Very Good

(23 reviews)

"Great hosts. Place was comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Vicky W.

$288 nightly

$308 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-The-Cozy-Family-Retreat.h100818493.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/97000000/96670000/96666500/96666416/9a628f50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96670000/96666500/96666416/w2046h3071x2y0-9d212a09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/97000000/96670000/96666500/96666416/86da7218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/97000000/96670000/96666500/96666416/96865d72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Augusta

[](https://www.expedia.com/Augusta-Hotels-Cozy-And-Modern-Augusta-Hideaway-Near-Wineries-And-Katy-Trail.h96666416.Hotel-Information)

10/10

Exceptional

(35 reviews)

"Great place to stay in Augusta"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William D.

$350 nightly

$373 total

Mar 10 - Mar 11

Total with taxes and fees

[](https://www.expedia.com/Augusta-Hotels-Cozy-And-Modern-Augusta-Hideaway-Near-Wineries-And-Katy-Trail.h96666416.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/eaf810ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/95cd9c8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/4d333dda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/d4e26647.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Wentzville

[](https://www.expedia.com/St-Louis-Hotels-4-Bedroom-Wentzville-Home-By-StayLage.h102252443.Hotel-Information)

9.8/10

Exceptional

(6 reviews)

"Amazing for attending the fireworks festivals nearby. Great shops walking distance for coffee and food"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tom K.

$470 nightly

$518 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-4-Bedroom-Wentzville-Home-By-StayLage.h102252443.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/55000000/54020000/54013100/54013002/6b7c086f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, Netflix, Hulu, streaming services](https://images.trvl-media.com/lodging/55000000/54020000/54013100/54013002/9fe9c14a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/55000000/54020000/54013100/54013002/6ceb4576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/55000000/54020000/54013100/54013002/89a643a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Villa Ridge

[](https://www.expedia.com/Villa-Ridge-Hotels-Fox-Haus-Near-Purina.h54013002.Hotel-Information)

9.8/10

Exceptional

(46 reviews)

"We really enjoyed the house and property we were in for AKC Rally National Championships and the location was perfect. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lisa S.

$246 nightly

$261 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Villa-Ridge-Hotels-Fox-Haus-Near-Purina.h54013002.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/76000000/75200000/75190800/75190737/049741ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/76000000/75200000/75190800/75190737/8112c5ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/76000000/75200000/75190800/75190737/27db235b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/76000000/75200000/75190800/75190737/3594dbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Washington

[](https://www.expedia.com/Washington-Hotels-Cozy-Little-House-Blocks-From-The-Park-Fair-Grounds.h75190737.Hotel-Information)

10/10

Exceptional

(61 reviews)

"Amazing host, clean easy access. Will stay here again if available"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeanie S.

$234 nightly

$252 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Washington-Hotels-Cozy-Little-House-Blocks-From-The-Park-Fair-Grounds.h75190737.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-22&endDate=2026-03-23&regionId=6353634&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=CABIN)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=COTTAGE)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=APARTMENT)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=CONDO)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=APART_HOTEL)

Chalets

[](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=CHALET)

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## Top Defiance Hotel Reviews

![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg)

### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent

"Nice staff"

[](https://expedia.com/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information)

![Drury Plaza Hotel St. Louis Chesterfield](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/69d580ec_y.jpg)

### Drury Plaza Hotel St. Louis Chesterfield

8/10 Good

"The staff was super friendly and professional and we had a great start. The breakfast was not great; food was cold and some of it didn’t seem fresh. Overall it was still a good stay!"

[](https://expedia.com/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information)

![Crowne Plaza St. Louis Airport by IHG](https://images.trvl-media.com/lodging/1000000/10000/3100/3010/45ba14e8_y.jpg)

### Crowne Plaza St. Louis Airport by IHG

4/10 Poor

"No hot water day of checkout, furniture and walls in room in poor condition, could not print receipt at checkout."

[](https://expedia.com/St-Louis-Hotels-Crowne-Plaza-St-Louis-Airport.h3010.Hotel-Information)

![Drury Inn & Suites Southwest St. Louis](https://images.trvl-media.com/lodging/1000000/980000/976200/976140/416a6a90_y.jpg)

### Drury Inn & Suites Southwest St. Louis

10/10 Excellent

"Clean room, great kickback and breakfast. "

[](https://expedia.com/St-Louis-Hotels-Drury-Inn-Suites-Southwest-St-Louis.h976140.Hotel-Information)

![Comfort Suites St Charles - St Louis](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/6093d918_y.jpg)

### Comfort Suites St Charles - St Louis

8/10 Good

"Allen at the front desk (manager?) was great! Very nice, welcoming, knows what he's doing. Only thing I'd mention is that the room was super clean, but whatever they're using to clean it stuck around. Smelled like hospital-level disinfectant. So, you know it's clean, but it's just a really intense smell that sticks around the whole time. "

[](https://expedia.com/St-Louis-Hotels-Comfort-Suites-St-Charles-St-Louis.h664414.Hotel-Information)

![Country Inn & Suites by Radisson, St. Charles Historic District](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/001d26f2_y.jpg)

### Country Inn & Suites by Radisson, St. Charles Historic District

8/10 Good

"Good "

[](https://expedia.com/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information)

![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/035dee6c_y.jpg)

### The Wildwood Hotel

10/10 Excellent

"2nd time was as good as the first. "

[](https://expedia.com/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information)

![Sonesta ES Suites St. Louis - Chesterfield](https://images.trvl-media.com/lodging/1000000/10000/500/422/6f160867_y.jpg)

### Sonesta ES Suites St. Louis - Chesterfield

8/10 Good

"Good"

[](https://expedia.com/St-Louis-Hotels-Sonesta-ES-Suites-St-Louis-Chesterfield.h422.Hotel-Information)

![Elimwood Hotel, a Ramada by Wyndham](https://images.trvl-media.com/lodging/1000000/30000/25500/25401/6eb87806_y.jpg)

### Elimwood Hotel, a Ramada by Wyndham

6/10 Okay

"Room was clean"

[](https://expedia.com/St-Louis-Hotels-Elimwood-Hotel.h25401.Hotel-Information)

## Find out more about Defiance

**Everything you need to know about Defiance vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Defiance vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Defiance vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Defiance vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Defiance. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Defiance in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $212 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Defiance rentals**

At Expedia, we put the best Defiance vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Defiance rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Defiance vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Defiance. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

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- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Vacation Homes in Defiance ](https://expedia.com/Defiance-Private-Vacation-Homes.d6353634-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Chalets in Defiance ](https://expedia.com/Defiance-Chalets.d6353634-aaChalets.Travel-Guide-Accommodation)
- [Apartments in Defiance ](https://expedia.com/Defiance-Apartments.d6353634-aaApartments.Travel-Guide-Accommodation)
- [Condo Rentals in Defiance ](https://expedia.com/Defiance-Condos.d6353634-aaCondos.Travel-Guide-Accommodation)
- [Cottages in Defiance ](https://expedia.com/Defiance-Cottages.d6353634-aaCottages.Travel-Guide-Accommodation)
- [Cabin Rentals in Defiance ](https://expedia.com/Defiance-Cabins.d6353634-aaCabins.Travel-Guide-Accommodation)
- [B&B in Defiance ](https://expedia.com/Defiance-Bed-And-Breakfast.d6353634-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Motels in Defiance ](https://expedia.com/Defiance-Motels.d6353634-aaMotels.Travel-Guide-Accommodation)
- [Aparthotels in Defiance ](https://expedia.com/Defiance-Apart-Hotels.d6353634-aaApartHotels.Travel-Guide-Accommodation)
- [Villas in Defiance ](https://expedia.com/Defiance-Villas.d6353634-aaVillas.Travel-Guide-Accommodation)
- [Lodges in Defiance ](https://expedia.com/Defiance-Lodges.d6353634-aaLodges.Travel-Guide-Accommodation)
- [Inns in Defiance ](https://expedia.com/Defiance-Inns.d6353634-aaInns.Travel-Guide-Accommodation)
- [Hostels in Defiance ](https://expedia.com/Defiance-Hostels.d6353634-aaHostels.Travel-Guide-Accommodation)
- [Resorts in Defiance ](https://expedia.com/Defiance-Resorts.d6353634-aaResorts.Travel-Guide-Accommodation)
- [Guest Houses in Defiance ](https://expedia.com/Defiance-Guest-Houses.d6353634-aaGuestHouses.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find vacation rentals in Defiance?

### What are some of the best vacation home rentals that Defiance has to offer?

### How many vacation rentals will I find in Defiance?

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