Vacation Rentals in Santa Cruz County

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Top Cities in Santa Cruz County

Top Vacation Rentals in Santa Cruz County

Vacation Home in Sonoita

10.0 out of 10, Exceptional, (157)
"Wonderful getaway weekend!"
United States
Deborah L.
Enjoy Agave House, a 2 BR w/2 en suite baths in the shadow of Mt. Wrightson

Vacation Home in Tubac

9.8 out of 10, Exceptional, (131)
"Excellent location and beautiful home. Would definitely stay there again."
United States
Karen Y.
Private Desert Gem, Just A 1/2 Mile From Tubac Golf Resort And Spa

Mobile Home in Patagonia

9.8 out of 10, Exceptional, (29)
"Donna & Howard were awesome hosts very attentive and friendly. Just a short drive to Sonoita and wineries or if you are just looking for some peace and solitude, this is it!!! "
United States
Krista I.
$110 nightly
The price is $116
Dec 8 - Dec 9
Total with taxes and fees
New Vintage Trailer on 40 acre horse ranch close to wineries and fun outings.

Vacation Home in Sonoita

9.4 out of 10, Exceptional, (8)
"Downtown Sonita Casita exceeded expectations. Very quant and beautiful inside and out. Dining and shopping all within walking or a short five minute drive. The morning view from the front yard is amazing. We will be back! "
United States
Russell
Downtown Sonoita Casita

Cabin in Sonoita

10.0 out of 10, Exceptional, (84)
"This is a lovely, quiet little place. we hope to return again soon."
United States
Jesse M.
$192 nightly
The price is $203
Dec 7 - Dec 8
Total with taxes and fees
for animal lovers - cute, little Bunkhouse attached to the horse barn

Vacation Home in Tubac

10.0 out of 10, Exceptional, (13)
"Beautiful property, clean, well kept and host was very accommodating. Would highly recommend. "
United States
Charles W.
Southwest Paradise

Vacation Home in Tumacacori-Carmen

9.8 out of 10, Exceptional, (13)
"Easily the best Vrbo property and experience we have ever had. Wonderfully unique and inviting. Looking forward to coming back"
United States
Bert B.
Spacious 4-bedroom house with AC and WiFi in charming Tumacacori-Carmen

Vacation Home in Rio Rico

9.8 out of 10, Exceptional, (51)
"We had a wonderful stay! Check-in and Check-out were very simple. Very clean and beautiful home! Owner was very responsive and pro-active to make certain our stay was nice! Would love to stay here again! Beautiful views!!!"
United States
Mark S.
Charming home with stunning views!

Cottage in Elgin

3.0 star property
10.0 out of 10, Exceptional, (1)
"The owner was easy to communicate with. Well-stocked kitchen. Comfy cottage. Really enjoyed sitting out at night to look at the starry night sky. We were in close driving distance to a few small towns."
United States
wendy
Walk to Wineries: Elgin Wine Country Retreat!

Vacation Home in Sonoita

9.8 out of 10, Exceptional, (43)
"We enjoyed our short stay whilst visiting family in the area."
United States
Mathew W.
$202 nightly
The price is $213
Dec 7 - Dec 8
Total with taxes and fees
Dogwood Flats - A cozy guest house in the oak trees!

Cottage in Elgin

10.0 out of 10, Exceptional, (37)
"This property is absolutely wonderful. Clean, peaceful, comfortable and welcoming. "
United States
Jen F.
$210 nightly
The price is $223
Jan 1 - Jan 2, 2026
Total with taxes and fees
Anam Cara Vineyard. Romantic Vineyard Cottage with sweeping views

Vacation Home in Rio Rico

9.0 out of 10, Wonderful, (7)
"Amazing place with an amazing hosts."
United States
Richard R.
$420 nightly
The price is $444
Dec 8 - Dec 9
Total with taxes and fees
Desert Oasis Retreat

Apartment in Patagonia

3.0 star property
10.0 out of 10, Exceptional, (2)
"Greeted by the neighboring horses was a special treat. Very quiet and secluded nestled in a mesquite bosque. Cute place close to walkable groceries, shops, and hikes. "
United States
corey
Peaceful & Historic Home in Patagonia!

Vacation Home in Madera Canyon

10.0 out of 10, Exceptional, (86)
"Perfect for birding, relaxing, enjoying quiet. Almost have to see to believe. A rare find."
United States
S. D.
Madera Canyon home w/ spectacular mountain view

Cottage in Elgin

3.0 star property
Pastoral Elgin Escape w/ Covered Patio & Grill!

Apartment in Sahuarita

9.8 out of 10, Exceptional, (37)
"Simple place to come back to and rest. Great location to take off from to set out for local adventures."
United States
LUKE G.
A cute and functional space located on beautiful 2.5 acres

Vacation Home in Benson

9.8 out of 10, Exceptional, (65)
"Beautiful home. Clean and spacious "
United States
Linda
$259 nightly
The price is $285
Dec 7 - Dec 8
Total with taxes and fees
Beautiful Benson Getaway with Hot Tub

Vacation Home in Amado

Charming bungalow in fabulous Amado with AC . Located between Tubac and Tucson

Vacation Home in Sahuarita

9.8 out of 10, Exceptional, (36)
"Love this place! It’s the second time we have stayed there. "
United States
Joanne C.
$229 nightly
The price is $249
Dec 12 - Dec 13
Total with taxes and fees
Sahuartia Retreat - Massage Chair, Gym and Pool/Hot Tub

Vacation Home in Corona de Tucson

10.0 out of 10, Exceptional, (14)
"Beautiful place, very relaxing environment. We wished we could have stayed longer The basket of snacks was above and beyond! "
United States
Norma R.
$228 nightly
The price is $252
Dec 7 - Dec 8
Total with taxes and fees
Cozy hideaway nestled in the heart of the Santa Rita Mountains,
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz County Hotel Reviews

Find out more about Santa Cruz County

Discover your perfect Santa Cruz County vacation rental with Expedia

How many vacation rentals are available in Santa Cruz County?


Expedia has plenty of vacation rentals to choose from in and around  Santa Cruz County, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Santa Cruz County?


The selection of Santa Cruz County vacation rentals we have selected for you start as low as $116 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Santa Cruz County?


Vacation rentals in Santa Cruz County come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Santa Cruz County vacation rentals to suit everyone. 


Why should I choose a vacation rental in Santa Cruz County?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Santa Cruz County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Santa Cruz County?


Find vacation rentals in Santa Cruz County by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Santa Cruz County.  


What amenities are available in a vacation rental in Santa Cruz County?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Santa Cruz County vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Santa Cruz County?   


Everytime is a great time to head to Santa Cruz County! Staying in a Santa Cruz County vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Santa Cruz County. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Santa Cruz County vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Santa Cruz County, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Santa Cruz County vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.