Title:  Essence Car Rental Car Rentals in South San Diego - Expedia.com

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#  Essence Car Rental Car Rentals in South San Diego

Photo by Elizabeth Bagnas

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Change your mind  
Penalty-free cancellation on many/select car rentals
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One Key members save 10% or more on over 1 million car rentals  
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Compare car suppliers and package your flight, hotel, and car to save

At Expedia, we are proud to work with Essence Car Rental due to their history of superior customer service as well their large fleet of premier vehicles. Start browsing through the great selection of rental cars by entering your search preferences into our online booking wizard and sorting through everything from spacious SUVs to compact luxury cars. Meaning, whether you need an economy car for a quick business trip or a roomy vehicle to fit the entire family on a long road trip, we’ve got you covered. And, what’s more, we always offer Essence Car Rental South San Diego cars at the lowest possible prices. Our prices on Essence Car Rental rentals in South San Diego can’t be beat. Get started and peruse our myriad of cheap deals and discounts on rental cars for your time in South San Diego today.

## Essence Car Rental Car Rental Information

| Car Supplier:                                     | Essence Car Rental                                                                                      |
| ------------------------------------------------- | ------------------------------------------------------------------------------------------------------- |
| Price:                                            |                                                                                                         |
| From the airport to your hotel:                   | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) |
| From popular domestic and international airports: | [Airport Car Rentals](https://www.expedia.com/lp/b/car-rental/airport)                                  |

## Frequently asked questions

### What type of car can I rent in South San Diego with Essence Car Rental?

### How can I get a cheap Essence Car Rental rental car in South San Diego with Expedia?

### How much does it cost to rent a car with Essence Car Rental in South San Diego?

### Why should I rent an Essence Car Rental vehicle through Expedia?

### What happens if I need to cancel my Essence Car Rental rental car reservation?

## Explore a world of travel with Expedia

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- [San Diego County Hotels ](https://www.expedia.com/Destinations-In-San-Diego-County.d178304.Hotel-Destinations)
- [Hotels near Otay ](https://www.expedia.com/Otay-Chula-Vista-Hotels.0-n177685-0.Travel-Guide-Filter-Hotels)
- [Hotels with a Pool in Otay ](https://www.expedia.com/Otay-Chula-Vista-Hotels-Hotel-With-Pool.0-n177685-0-tHotelwithPool.Travel-Guide-Filter-Hotels)
- [Hotels with Free Parking in Otay ](https://www.expedia.com/Otay-Chula-Vista-Hotels-Hotels-With-Free-Parking.0-n177685-0-tHotelswithFreeParking.Travel-Guide-Filter-Hotels)
- [Hotels & Resorts for Couples in Otay ](https://www.expedia.com/Otay-Chula-Vista-Hotels-Couples-Resorts-Hotels.0-n177685-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
- [San Diego Hotels ](https://www.expedia.com/San-Diego-Hotels.d3073.Travel-Guide-Hotels)
- [Hotels near Castle Park ](https://www.expedia.com/Castle-Park-Chula-Vista-Hotels.0-n177686-0.Travel-Guide-Filter-Hotels)
- [Hotels near Otay Mesa West ](https://www.expedia.com/Otay-Mesa-West-San-Diego-Hotels.0-n553248625809641010-0.Travel-Guide-Filter-Hotels)
- [Hilton Hotels in Otay Mesa West ](https://www.expedia.com/Otay-Mesa-West-San-Diego-Hotels-Hilton-Hotels.0-n553248625809641010-0--bHiltonHotels.Travel-Guide-Filter-Hotels)
- [Gay friendly Hotels in Otay Mesa West ](https://www.expedia.com/Otay-Mesa-West-San-Diego-Hotels-LGBT-Welcoming-Hotel.0-n553248625809641010-0-tLGBTWelcomingHotel.Travel-Guide-Filter-Hotels)
- [Extended Stay Hotels in Otay Mesa West ](https://www.expedia.com/Otay-Mesa-West-San-Diego-Hotels-Extended-Stay-Hotels.0-n553248625809641010-0-tExtendedStayHotels.Travel-Guide-Filter-Hotels)
- [Hotels near Kaiser Permanente Otay Mesa Medical Offices ](https://www.expedia.com/Kaiser-Permanente-Otay-Mesa-Medical-Offices-Hotels.0-l553248634333595416-0.Travel-Guide-Filter-Hotels)
- [Gay friendly Hotels in Palm City ](https://www.expedia.com/Palm-City-San-Diego-Hotels-LGBT-Welcoming-Hotel.0-n553248635976470391-0-tLGBTWelcomingHotel.Travel-Guide-Filter-Hotels)
- [Hotels near Palm City ](https://www.expedia.com/Palm-City-San-Diego-Hotels.0-n553248635976470391-0.Travel-Guide-Filter-Hotels)
- [Hotels near Palomar St Trolley Station ](https://www.expedia.com/Palomar-St-Trolley-Station-Hotels.d6186822.Travel-Guide-Hotels)
- [Hotels near Len Moore Skate Park ](https://www.expedia.com/Len-Moore-Skate-Park-Hotels.0-l6266345-0.Travel-Guide-Filter-Hotels)
- [Hotels near Palm Ave Trolley Station ](https://www.expedia.com/Palm-Ave-Trolley-Station-Hotels.d6186824.Travel-Guide-Hotels)
- [Apartments in Palm Ave Trolley Station ](https://www.expedia.com/Palm-Ave-Trolley-Station-Apartments.d6186824-aaApartments.Travel-Guide-Accommodation)
- [Cottages in Palm Ave Trolley Station ](https://www.expedia.com/Palm-Ave-Trolley-Station-Cottages.d6186824-aaCottages.Travel-Guide-Accommodation)
- [Resorts in Palm Ave Trolley Station ](https://www.expedia.com/Palm-Ave-Trolley-Station-Resorts.d6186824-aaResorts.Travel-Guide-Accommodation)
- [Hotels near Iris Avenue Trolley Station ](https://www.expedia.com/Iris-Avenue-Trolley-Station-Hotels.d6186826.Travel-Guide-Hotels)
- [Apartments in Iris Avenue Trolley Station ](https://www.expedia.com/Iris-Avenue-Trolley-Station-Apartments.d6186826-aaApartments.Travel-Guide-Accommodation)
- [Vacation Homes in Iris Avenue Trolley Station ](https://www.expedia.com/Iris-Avenue-Trolley-Station-Private-Vacation-Homes.d6186826-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Chula Vista Hotels ](https://www.expedia.com/Chula-Vista-Hotels.d7442.Travel-Guide-Hotels)
- [Hotels near Sharp Chula Vista Medical Center ](https://www.expedia.com/Sharp-Chula-Vista-Medical-Center-Hotels.0-l553248621560505607-0.Travel-Guide-Filter-Hotels)
- [Hotels near Ocean View Hills ](https://www.expedia.com/Ocean-View-Hills-San-Diego-Hotels.0-n553248635976008220-0.Travel-Guide-Filter-Hotels)
- [Hotels near Nestor ](https://www.expedia.com/Nestor-San-Diego-Hotels.0-n553248635976476281-0.Travel-Guide-Filter-Hotels)
- [Hotels near North Island Credit Union Amphitheatre ](https://www.expedia.com/North-Island-Credit-Union-Amphitheatre-Hotels.0-l6128061-0.Travel-Guide-Filter-Hotels)
- [Hotels near Beyer Blvd Trolley Station ](https://www.expedia.com/Beyer-Blvd-Trolley-Station-Hotels.d6186828.Travel-Guide-Hotels)
- [Apartments in Beyer Blvd Trolley Station ](https://www.expedia.com/Beyer-Blvd-Trolley-Station-Apartments.d6186828-aaApartments.Travel-Guide-Accommodation)
- [Motels in Beyer Blvd Trolley Station ](https://www.expedia.com/Beyer-Blvd-Trolley-Station-Motels.d6186828-aaMotels.Travel-Guide-Accommodation)
- [Hotels near Chula Vista Center ](https://www.expedia.com/Chula-Vista-Center-Hotels.0-l553248621560505608-0.Travel-Guide-Filter-Hotels)
- [Hotels near White Water Canyon ](https://www.expedia.com/White-Water-Canyon-Hotels.0-l553248621532638602-0.Travel-Guide-Filter-Hotels)
- [San Ysidro Hotels ](https://www.expedia.com/San-Ysidro-Hotels.d8380.Travel-Guide-Hotels)
- [Cheap Hotels in Chula Vista ](https://www.expedia.com/Chula-Vista-Hotels-Cheap-Hotels.0-0-d7442-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in San Ysidro ](https://www.expedia.com/San-Ysidro-Hotels-Cheap-Hotels.0-0-d8380-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Hotels near Atlantis Laser Tag ](https://www.expedia.com/Atlantis-Laser-Tag-Hotels.0-l553248621532638600-0.Travel-Guide-Filter-Hotels)
- [Imperial Beach Hotels ](https://www.expedia.com/Imperial-Beach-Hotels.d177683.Travel-Guide-Hotels)
- [Motels in San Ysidro ](https://www.expedia.com/San-Ysidro-Motels.d8380-aaMotels.Travel-Guide-Accommodation)
- [Pet-friendly Hotels in San Ysidro ](https://www.expedia.com/San-Ysidro-Hotels-Pet-Friendly-Hotel.0-0-d8380-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Hostels in San Ysidro ](https://www.expedia.com/San-Ysidro-Hostels.d8380-aaHostels.Travel-Guide-Accommodation)

- [Flights to San Diego ](https://www.expedia.com/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)
- [Flights to San Ysidro ](https://www.expedia.com/Cheap-Flights-To-San-Ysidro.d8380.Travel-Guide-Flights)
- [Flights from San Ysidro ](https://www.expedia.com/lp/flights/8380/flights-from-san-ysidro)

- [Visit Otay ](https://www.expedia.com/Chula-Vista-Otay.dx177685)
- [Visit Castle Park ](https://www.expedia.com/Chula-Vista-Castle-Park.dx177686)
- [Visit Otay Mesa West ](https://www.expedia.com/San-Diego-Otay-Mesa-West.dx553248625809641010)
- [Kaiser Permanente Otay Mesa Medical Offices ](https://www.expedia.com/Kaiser-Permanente-Otay-Mesa-Medical-Offices-Ocean-View-Hills.d553248634333595416.Vacation-Attraction)
- [Len Moore Skate Park ](https://www.expedia.com/Len-Moore-Skate-Park-Chula-Vista.d6266345.Vacation-Attraction)
- [White Water Canyon ](https://www.expedia.com/White-Water-Canyon-Chula-Vista.d553248621532638602.Vacation-Attraction)
- [North Island Credit Union Amphitheatre ](https://www.expedia.com/North-Island-Credit-Union-Amphitheatre-Chula-Vista.d6128061.Vacation-Attraction)
- [Atlantis Laser Tag ](https://www.expedia.com/Atlantis-Laser-Tag-Chula-Vista.d553248621532638600.Vacation-Attraction)
- [Visit San Ysidro ](https://www.expedia.com/San-Ysidro.dx8380)
- [San Ysidro Vacations ](https://www.expedia.com/San-Ysidro.d8380.Destination-Travel-Guides)

- [Avis Rental Cars in Otay ](https://www.expedia.com/Avis-Car-Rentals-In-Otay.d177685-c41.Car-Rental-Guide-Suppliers)
- [Hertz Rental Cars in Otay ](https://www.expedia.com/Hertz-Car-Rentals-In-Otay.d177685-c40.Car-Rental-Guide-Suppliers)
- [Mex Rent A Car Rental Cars in Otay ](https://www.expedia.com/Mex-Rent-A-Car-Car-Rentals-In-Otay.d177685-c1084.Car-Rental-Guide-Suppliers)
- [Budget Rental Cars in Otay ](https://www.expedia.com/Budget-Car-Rentals-In-Otay.d177685-c39.Car-Rental-Guide-Suppliers)
- [Car rentals near Otay ](https://www.expedia.com/Car-Rentals-In-Otay.d177685.Car-Rental-Guide)
- [Sportscar Car Rentals in Otay ](https://www.expedia.com/Sportscar-Car-Rentals-In-Otay.d177685-tSportscar.Car-Rental-Guide-Class)
- [Car rentals near San Diego ](https://www.expedia.com/Car-Rentals-In-San-Diego.d3073.Car-Rental-Guide)
- [Car rentals near Otay Mesa West ](https://www.expedia.com/Car-Rentals-In-Otay-Mesa-West.d553248625809641010.Car-Rental-Guide)
- [Car rentals near Kaiser Permanente Otay Mesa Medical Offices ](https://www.expedia.com/Car-Rentals-In-Kaiser-Permanente-Otay-Mesa-Medical-Offices.d553248634333595416.Car-Rental-Guide)
- [Car rentals near Len Moore Skate Park ](https://www.expedia.com/Car-Rentals-In-Len-Moore-Skate-Park.d6266345.Car-Rental-Guide)
- [National Car Rental Rental Cars in Nestor ](https://www.expedia.com/National-Car-Rental-Car-Rentals-In-Nestor.d553248635976476281-c42.Car-Rental-Guide-Suppliers)
- [Car rentals near Sharp Chula Vista Medical Center ](https://www.expedia.com/Car-Rentals-In-Sharp-Chula-Vista-Medical-Center.d553248621560505607.Car-Rental-Guide)
- [Car rentals near Chula Vista ](https://www.expedia.com/Car-Rentals-In-Chula-Vista.d7442.Car-Rental-Guide)
- [Enterprise Rental Cars in San Ysidro ](https://www.expedia.com/Enterprise-Car-Rentals-In-San-Ysidro.d8380-c15.Car-Rental-Guide-Suppliers)
- [Fox Rental Cars Rental Cars in San Ysidro ](https://www.expedia.com/Fox-Rental-Cars-Car-Rentals-In-San-Ysidro.d8380-c19.Car-Rental-Guide-Suppliers)
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- [National Car Rental Rental Cars in San Ysidro ](https://www.expedia.com/National-Car-Rental-Car-Rentals-In-San-Ysidro.d8380-c42.Car-Rental-Guide-Suppliers)
- [Dollar Rent A Car Rental Cars in San Ysidro ](https://www.expedia.com/Dollar-Rent-A-Car-Car-Rentals-In-San-Ysidro.d8380-c43.Car-Rental-Guide-Suppliers)
- [Thrifty Car Rental Rental Cars in San Ysidro ](https://www.expedia.com/Thrifty-Car-Rental-Car-Rentals-In-San-Ysidro.d8380-c45.Car-Rental-Guide-Suppliers)
- [Budget Rental Cars in San Ysidro ](https://www.expedia.com/Budget-Car-Rentals-In-San-Ysidro.d8380-c39.Car-Rental-Guide-Suppliers)
- [Sixt Rental Cars in San Ysidro ](https://www.expedia.com/Sixt-Car-Rentals-In-San-Ysidro.d8380-c35.Car-Rental-Guide-Suppliers)
- [Essence Car Rental Rental Cars in San Ysidro ](https://www.expedia.com/Essence-Car-Rental-Car-Rentals-In-San-Ysidro.d8380-c1085.Car-Rental-Guide-Suppliers)
- [Alamo Rent A Car Rental Cars in San Ysidro ](https://www.expedia.com/Alamo-Rent-A-Car-Car-Rentals-In-San-Ysidro.d8380-c6.Car-Rental-Guide-Suppliers)
- [Dollar Rental Cars in San Ysidro ](https://www.expedia.com/Dollar-Car-Rentals-In-San-Ysidro.d8380-c1091.Car-Rental-Guide-Suppliers)
- [Enterprise Rental Cars in Chula Vista ](https://www.expedia.com/Enterprise-Car-Rentals-In-Chula-Vista.d7442-c15.Car-Rental-Guide-Suppliers)
- [Hertz Rental Cars in Chula Vista ](https://www.expedia.com/Hertz-Car-Rentals-In-Chula-Vista.d7442-c40.Car-Rental-Guide-Suppliers)
- [Car rentals near North Island Credit Union Amphitheatre ](https://www.expedia.com/Car-Rentals-In-North-Island-Credit-Union-Amphitheatre.d6128061.Car-Rental-Guide)
- [Budget Rental Cars in Chula Vista ](https://www.expedia.com/Budget-Car-Rentals-In-Chula-Vista.d7442-c39.Car-Rental-Guide-Suppliers)
- [Avis Rental Cars in Chula Vista ](https://www.expedia.com/Avis-Car-Rentals-In-Chula-Vista.d7442-c41.Car-Rental-Guide-Suppliers)
- [Dollar Rent A Car Rental Cars in Chula Vista ](https://www.expedia.com/Dollar-Rent-A-Car-Car-Rentals-In-Chula-Vista.d7442-c43.Car-Rental-Guide-Suppliers)
- [National Car Rental Rental Cars in Chula Vista ](https://www.expedia.com/National-Car-Rental-Car-Rentals-In-Chula-Vista.d7442-c42.Car-Rental-Guide-Suppliers)
- [Thrifty Car Rental Rental Cars in Chula Vista ](https://www.expedia.com/Thrifty-Car-Rental-Car-Rentals-In-Chula-Vista.d7442-c45.Car-Rental-Guide-Suppliers)
- [Alamo Rent A Car Rental Cars in Chula Vista ](https://www.expedia.com/Alamo-Rent-A-Car-Car-Rentals-In-Chula-Vista.d7442-c6.Car-Rental-Guide-Suppliers)
- [Mex Rent A Car Rental Cars in Chula Vista ](https://www.expedia.com/Mex-Rent-A-Car-Car-Rentals-In-Chula-Vista.d7442-c1084.Car-Rental-Guide-Suppliers)
- [Sixt Rental Cars in Chula Vista ](https://www.expedia.com/Sixt-Car-Rentals-In-Chula-Vista.d7442-c35.Car-Rental-Guide-Suppliers)
- [Payless Rental Cars in Chula Vista ](https://www.expedia.com/Payless-Car-Rentals-In-Chula-Vista.d7442-c38.Car-Rental-Guide-Suppliers)
- [Rent A Wreck Rental Cars in Chula Vista ](https://www.expedia.com/Rent-A-Wreck-Car-Rentals-In-Chula-Vista.d7442-c33.Car-Rental-Guide-Suppliers)
- [Fox Rental Cars Rental Cars in Chula Vista ](https://www.expedia.com/Fox-Rental-Cars-Car-Rentals-In-Chula-Vista.d7442-c19.Car-Rental-Guide-Suppliers)
- [Europcar Rental Cars in Chula Vista ](https://www.expedia.com/Europcar-Car-Rentals-In-Chula-Vista.d7442-c14.Car-Rental-Guide-Suppliers)
- [Enterprise Rental Cars in Imperial Beach ](https://www.expedia.com/Enterprise-Car-Rentals-In-Imperial-Beach.d177683-c15.Car-Rental-Guide-Suppliers)
- [Hertz Rental Cars in Imperial Beach ](https://www.expedia.com/Hertz-Car-Rentals-In-Imperial-Beach.d177683-c40.Car-Rental-Guide-Suppliers)
- [Thrifty Car Rental Rental Cars in Imperial Beach ](https://www.expedia.com/Thrifty-Car-Rental-Car-Rentals-In-Imperial-Beach.d177683-c45.Car-Rental-Guide-Suppliers)
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- [Car rentals near San Ysidro ](https://www.expedia.com/Car-Rentals-In-San-Ysidro.d8380.Car-Rental-Guide)

- [Things to do in San Ysidro ](https://www.expedia.com/Things-To-Do-In-San-Ysidro.d8380.Travel-Guide-Activities)
- [Things to do in Chula Vista ](https://www.expedia.com/Things-To-Do-In-Chula-Vista.d7442.Travel-Guide-Activities)

Heading to South San Diego? Explore South San Diego with Expedia's Travel Guides to find the best hotels, vacation packages, car rental deals and more!

[Flights to South San Diego

](https://expedia.com/Cheap-Flights-To-South-San-Diego.d553248632063518562.Travel-Guide-Flights)[

South San Diego Hotels

](https://expedia.com/South-San-Diego-Hotels.d553248632063518562.Travel-Guide-Hotels)[

Vacation Rentals in South San Diego

](https://expedia.com/South-San-Diego-Vacation-Rentals.d553248632063518562.Travel-Guide-VacationRentals)[

Car Rentals in South San Diego

](https://expedia.com/Car-Rentals-In-South-San-Diego.d553248632063518562.Car-Rental-Guide)[

South San Diego Vacations

](https://expedia.com/South-San-Diego.d553248632063518562.Destination-Travel-Guides)[

Things to do in South San Diego

](https://expedia.com/Things-To-Do-In-South-San-Diego.d553248632063518562.Travel-Guide-Activities)