Default HTG hotel image

Lupus Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Nov 13 - Nov 15
In two months
Dec 25 - Dec 27
In three months
Jan 22 - Jan 24
In four months
Feb 19 - Feb 21

Our top choices for Lupus vacation rentals

An old brick building with a sign reading "Lupus General Store."

1. Quiet Riverfront Cottage on Missouri River

Quiet Riverfront Cottage on Missouri River
Jamestown
8.8 out of 10, Excellent, (17 reviews)
"It is a beautiful, quiet country setting and you can walk to the riverbank from the place."
United States
Patti M.
$171 nightly
The price is $183
Nov 9 - Nov 10
Total with taxes and fees
Quiet Riverfront Cottage on Missouri River
A two-story brick building with a sign reading "Lupus General Store".

2. Step Back in Time Near The Missouri River

Step Back in Time Near The Missouri River
Jamestown
9.8 out of 10, Exceptional, (24 reviews)
"Perfect spot!"
United States
Nicole
$272 nightly
The price is $289
Nov 9 - Nov 10
Total with taxes and fees
Step Back in Time Near The Missouri River
An open refrigerator with multiple shelves and a water dispenser.

3. 3 Bed 1.5 Bath Pet Friendly Apt

3 Bed 1.5 Bath Pet Friendly Apt
Columbia
10.0 out of 10, Exceptional, (13 reviews)
"Property was clean and comfortable and host was attentive."
United States
Stephanie A.
$174 nightly
The price is $174
Nov 4 - Nov 5
Total with taxes and fees
3 Bed 1.5 Bath Pet Friendly Apt
A stone-walled entrance with a white door, a number '3' sign, and a small outdoor light fixture.

4. Super Close to Mizzou Condo 2 Bed 1 Bath

Super Close to Mizzou Condo 2 Bed 1 Bath
Columbia
10.0 out of 10, Exceptional, (19 reviews)
"The stay was great. Clean, quiet, comfortable, well equipped. Also very convenient location"
United States
William
$190 nightly
The price is $190
Nov 8 - Nov 9
Total with taxes and fees
Super Close to Mizzou Condo 2 Bed 1 Bath
A narrow hallway with a wooden bench on the right, a rocking chair in the center, and a bed at the end.

5. The Katy Caboose in Hartsburg

The Katy Caboose in Hartsburg
Hartsburg
10.0 out of 10, Exceptional, (3 reviews)
"We had an amazing time on the trip! The host was amazing with communication and answering any questions that came up. The caboose itself was super comfortable and spacious. We really appreciated the pet friendly aspect and our dog had a wonderful time on the property!"
United States
Veronica R.
$187 nightly
The price is $198
Nov 3 - Nov 4
Total with taxes and fees
The Katy Caboose in Hartsburg
A kitchen with dark cabinets, a stainless steel refrigerator, a microwave, and a dishwasher.

6. ~A Home Away From Home~Sleeps 8~

~A Home Away From Home~Sleeps 8~
Columbia
9.6 out of 10, Exceptional, (8 reviews)
"VRBO was exactly as described. Check in was super easy, and communication with the host was seamless."
United States
Bryon L.
$262 nightly
The price is $277
Nov 3 - Nov 4
Total with taxes and fees
~A Home Away From Home~Sleeps 8~
A white entertainment center with a flat-screen TV, decorative items, and a remote control.

7. 10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!

10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!
Columbia
9.6 out of 10, Exceptional, (52 reviews)
"Very comfortable and friendly host!"
United States
Troy V.
$171 nightly
The price is $184
Nov 3 - Nov 4
Total with taxes and fees
10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!
A hallway with a blue-lit wall-mounted light fixture, a door leading to another room, and a wooden table in the foreground.

8. Como's Finest- A Home Away From Home- Sleeps 10

Como's Finest- A Home Away From Home- Sleeps 10
Columbia
9.4 out of 10, Exceptional, (8 reviews)
"Great place for a weekend trip"
United States
Brandon W.
$267 nightly
The price is $282
Nov 3 - Nov 4
Total with taxes and fees
Como's Finest- A Home Away From Home- Sleeps 10
A spacious living room with a brown sofa, wooden chairs, a coffee table, and a ceiling fan.

9. Quaint cottage w/ direct access to Katy Trail!

Quaint cottage w/ direct access to Katy Trail!
Hartsburg
10.0 out of 10, Exceptional, (2 reviews)
"They were so nice! Super clean, great place to stay!"
United States
Taylor R.
$199 nightly
The price is $211
Nov 29 - Nov 30
Total with taxes and fees
Quaint cottage w/ direct access to Katy Trail!
A hallway with a dining area, a door, a wall-mounted sign, a potted plant, and a small table with a lamp.

10. Comfy Home~Teal Feel~ Sleeps 8

Comfy Home~Teal Feel~ Sleeps 8
Columbia
8.4 out of 10, Very good, (8 reviews)
"Went there for work. Great place to stay. Loved the beds, very comfortable. I will stay there again when I come back."
United States
Kevin G.
$227 nightly
The price is $239
Nov 9 - Nov 10
Total with taxes and fees
Comfy Home~Teal Feel~ Sleeps 8
A spacious living area with a sofa, a patterned ottoman, and a fireplace.

11. Whispering Woods Hideaway ~ Large Home ~ 85 in TV

Whispering Woods Hideaway ~ Large Home ~ 85 in TV
Columbia
9.8 out of 10, Exceptional, (6 reviews)
"Clean house. Very responsive"
United States
Gary B.
$437 nightly
The price is $461
Nov 3 - Nov 4
Total with taxes and fees
Whispering Woods Hideaway ~ Large Home ~ 85 in TV
A modern kitchen with dark cabinets, stainless steel appliances, and a wooden dining table.

12. 3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena

3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
Columbia
9.6 out of 10, Exceptional, (16 reviews)
"Great place to stay! "
United States
Stacy B.
$310 nightly
The price is $327
Nov 4 - Nov 5
Total with taxes and fees
3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
A bedroom with a fireplace, a TV mounted above it, a bed with a blue blanket, and a blue armchair with a patterned pillow.

13. Historic Cozy Apartment 1 Bedroom In Peaceful Boonville

Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
Boonville
9.6 out of 10, Exceptional, (27 reviews)
"Apartment was clean and adequate for our stay. A bit tight for four people but would be fine for a couple."
United States
Bradley O.
$173 nightly
The price is $188
Nov 3 - Nov 4
Total with taxes and fees
Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
A staircase with wooden steps and white railings, leading to a second floor.

14. Restored 2-bedroom cottage in beautiful California, MO

Restored 2-bedroom cottage in beautiful California, MO
California
10.0 out of 10, Exceptional, (1 review)
"The house was warm & cozy, bed super comfortable. Very cute historic home, we enjoyed our stay!"
United States
Shelley F.
$190 nightly
The price is $206
Nov 3 - Nov 4
Total with taxes and fees
Restored 2-bedroom cottage in beautiful California, MO
A modern kitchen with a stainless steel refrigerator, wooden flooring, and a tiled backsplash.

15. Downtown Luxury Suite

Downtown Luxury Suite
Columbia
9.8 out of 10, Exceptional, (88 reviews)
"Wonderful locationFun spaceWe would definitely stay here again"
United States
Andrew M.
$196 nightly
The price is $220
Nov 3 - Nov 4
Total with taxes and fees
Downtown Luxury Suite
A compact kitchen with a refrigerator, sink, and stove, a dining table with chairs, and a view through a sliding glass door.

16. Cozy, well appointed 3-bedroom, 1.5-bath house 10 min from Mizzou

Cozy, well appointed 3-bedroom, 1.5-bath house 10 min from Mizzou
Columbia
10.0 out of 10, Exceptional, (5 reviews)
"The space was VERY clean. We walked about in bare feet, and our feet stayed clean. It really helped us to relax and enjoy the place. The kitchen was well stocked. We cooked a few times, and found all the utensils/pots and pans we needed. Beds were quite comfortable. While we could not walk to any thing, it was a very short drive to anything we wanted or needed (by short we mean less than 15 minutes). The neighborhood was quiet at night (even though it was during the 4th of July). The...
United States
Matt K.
$282 nightly
The price is $303
Nov 15 - Nov 16
Total with taxes and fees
Cozy, well appointed 3-bedroom, 1.5-bath house 10 min from Mizzou
A cozy bedroom with a bed, a wooden table, a chair, and a staircase.

17. Cozy cabin getaway with hot-tub under stars!

Cozy cabin getaway with hot-tub under stars!
Ashland
9.6 out of 10, Exceptional, (31 reviews)
"This is our second time staying here and we love it. Such a peaceful relaxing place."
United States
Ryan L.
$313 nightly
The price is $330
Nov 5 - Nov 6
Total with taxes and fees
Cozy cabin getaway with hot-tub under stars!
An outdoor patio area with wicker furniture, a fire pit, and a covered seating area.

18. Accessible Studio Suite w/ Breakfast Included, Near Mizzou

Accessible Studio Suite w/ Breakfast Included, Near Mizzou
Columbia
$158 nightly
The price is $177
Nov 8 - Nov 9
Total with taxes and fees
Accessible Studio Suite w/ Breakfast Included, Near Mizzou
An outdoor patio area with wicker furniture, a fire pit, and a covered seating area.

19. King Studio w/ Kitchen | Free Hot Breakfast + Pool

King Studio w/ Kitchen | Free Hot Breakfast + Pool
Columbia
$158 nightly
The price is $177
Nov 8 - Nov 9
Total with taxes and fees
King Studio w/ Kitchen | Free Hot Breakfast + Pool
An outdoor patio area with wicker furniture, a fire pit, and a covered seating area.

20. Near University of Missouri | Fitness Center + Breakfast Included

Near University of Missouri | Fitness Center + Breakfast Included
Columbia
9.4 out of 10, Exceptional, (3 reviews)
"The room was great! Bed was very comfortable. Very homey in a small space. The pool area is a bit dated. The hot tub steps are not the right cadence. I tripped into the very bottom as a result. So be careful there. Otherwise a great experience!"
United States
Sarah S.
$164 nightly
The price is $184
Nov 8 - Nov 9
Total with taxes and fees
Near University of Missouri | Fitness Center + Breakfast Included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Lupus Hotel Reviews

Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

8/10 Good
"The carpets are disgusting and the rooms need updated."
Trish 1-night trip
Posted 3 hours ago
Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

Find out more about Lupus

Everything you need to know about Lupus vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Lupus vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Lupus vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Lupus vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Lupus. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Lupus in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $183 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Lupus rentals

At Expedia, we put the best Lupus vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Lupus rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Lupus vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Lupus. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Lupus?

Yes, there are vacation rentals near the most popular points of interest in Lupus, or you can choose a secluded option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals that Lupus has to offer?

The Stone & Bridge: Close to MKT Trail & Dog Park, Dining, Groceries & I-70: This vacation home rental near Lupus offers a patio, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

What can I see and do in Lupus?

Explore the area and family-friendly sights such as Warm Springs Ranch, or get out into nature at a spot like Shelter Gardens. In the larger area, you’ll find Rock Bridge Memorial State Park and Mizzou Arena.

What are vacation rentals like in Lupus?

Vacation rentals are privately owned accommodations you can reserve for a few days or a quick weekend in Lupus. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, vacation rentals can provide a sense of privacy away from public hotel elevators and busy front desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive option for a family trip or a small group gathering.