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Our top choices for Lupus hotels

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO
2.5 star property
Columbia
8.2 out of 10, Very Good, (684 reviews)
"Friendly staff, hot Continental breakfast, clean rooms. Definitely one of the nicer baymonts we've booked into. "
Canada
Tracy
$60 nightly
The price is $67
Mar 15 - Mar 16
Total with taxes and fees
Baymont by Wyndham Columbia, MO

Ramada by Wyndham Columbia

Ramada by Wyndham Columbia
2.5 star property
Columbia
7.6 out of 10, Good, (1,008 reviews)
"Great, will be back next week"
United States
Matthew
$61 nightly
The price is $69
Mar 9 - Mar 10
Total with taxes and fees
Ramada by Wyndham Columbia

Best Western Plus Columbia Inn

Best Western Plus Columbia Inn
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,250 reviews)
"Very clean, smelled fresh, staff friendly!"
United States
Darci
$70 nightly
The price is $79
Mar 15 - Mar 16
Total with taxes and fees
Best Western Plus Columbia Inn

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,003 reviews)
"Great breakfast, great stay!!"
United States
Rebecca
$103 nightly
The price is $117
Mar 22 - Mar 23
Total with taxes and fees
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East
3.0 star property
Columbia
9.6 out of 10, Exceptional, (1,389 reviews)
"Great stay, very clean and very nice!"
United States
Joshua
$98 nightly
The price is $111
Mar 22 - Mar 23
Total with taxes and fees
Drury Plaza Hotel Columbia East

Tru By Hilton Columbia South

Tru By Hilton Columbia South
2.5 star property
Columbia
8.8 out of 10, Excellent, (6 reviews)
"Room was great! Clean and friendly staff"
United States
Tara
$106 nightly
The price is $121
Mar 15 - Mar 16
Total with taxes and fees
Tru By Hilton Columbia South

Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,755 reviews)
"Room, staff and breakfast were wonderful."
United States
Marvin
$85 nightly
The price is $96
Mar 15 - Mar 16
Total with taxes and fees
Country Inn & Suites by Radisson, Columbia, MO

Quality Inn & Suites Boonville - Columbia

Quality Inn & Suites Boonville - Columbia
2.5 star property
Boonville
7.4 out of 10, Good, (590 reviews)
"The room was clean, staff was super friendly, and the pool and hot tub were excellent"
United States
Kelsey
$93 nightly
The price is $105
Mar 9 - Mar 10
Total with taxes and fees
Quality Inn & Suites Boonville - Columbia

Days Inn by Wyndham Boonville

Days Inn by Wyndham Boonville
2.0 star property
Boonville
6.0 out of 10, (1,005 reviews)
"Quick and easy checkin, bed was great. "
United States
Darwyn
$42 nightly
The price is $47
Mar 9 - Mar 10
Total with taxes and fees
Days Inn by Wyndham Boonville

Quality Inn & Suites Columbia I-70

Quality Inn & Suites Columbia I-70
2.5 star property
Columbia
7.0 out of 10, Good, (844 reviews)
"Clean rooms and excellent service"
United States
Sarah
$57 nightly
The price is $64
Mar 15 - Mar 16
Total with taxes and fees
Quality Inn & Suites Columbia I-70

Super 8 by Wyndham Columbia East

Super 8 by Wyndham Columbia East
2.0 star property
Columbia
6.2 out of 10, (1,001 reviews)
"Very clean hotel with friendly and helpful staff "
United States
Deborah
$57 nightly
The price is $64
Mar 8 - Mar 9
Total with taxes and fees
Super 8 by Wyndham Columbia East

Comfort Suites Columbia - University Area

Comfort Suites Columbia - University Area
2.5 star property
Columbia
7.8 out of 10, Good, (968 reviews)
"Beds were comfortable, there was a lot of lobby construction which was a lot "
United States
Karen
$89 nightly
The price is $101
Mar 8 - Mar 9
Total with taxes and fees
Comfort Suites Columbia - University Area

Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia
3.0 star property
Columbia
9.0 out of 10, Wonderful, (1,236 reviews)
"Rooms were very clean & comfortable! "
United States
stefanie
$90 nightly
The price is $102
Mar 15 - Mar 16
Total with taxes and fees
Wingate by Wyndham - Columbia

Wyndham Executive Center Columbia

Wyndham Executive Center Columbia
3.5 star property
Columbia
8.4 out of 10, Very Good, (1,006 reviews)
"Clean great staff. They have a bar!!"
United States
Tom
$94 nightly
The price is $106
Mar 29 - Mar 30
Total with taxes and fees
Wyndham Executive Center Columbia

Drury Inn & Suites Columbia Stadium Boulevard

Drury Inn & Suites Columbia Stadium Boulevard
3.0 star property
Columbia
9.4 out of 10, Exceptional, (1,004 reviews)
"Excellent service and stay!"
United States
David
$100 nightly
The price is $113
Mar 15 - Mar 16
Total with taxes and fees
Drury Inn & Suites Columbia Stadium Boulevard

Holiday Inn Columbia East by IHG

Holiday Inn Columbia East by IHG
3.0 star property
Columbia
8.4 out of 10, Very Good, (1,002 reviews)
"Buffet breakfast was a great option and the staff working it were awesome! "
United States
Matthew
$101 nightly
The price is $115
Mar 8 - Mar 9
Total with taxes and fees
Holiday Inn Columbia East by IHG

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
3.0 star property
Boonville
8.4 out of 10, Very Good, (973 reviews)
"Always a good time and exceptional hotel"
United States
Nancy
$86 nightly
The price is $98
Apr 6 - Apr 7
Total with taxes and fees
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Hampton Inn Columbia

Hampton Inn Columbia
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,004 reviews)
"Everything was top notch from the room to the great breakfast. Convenient to find, easy parking close to room. Manager and staff very nice and helpful! I will definitely stay here again if in the area. "
United States
Teresa
$106 nightly
The price is $120
Mar 15 - Mar 16
Total with taxes and fees
Hampton Inn Columbia

Boonville Luxury Lodging

Boonville Luxury Lodging
4.0 star property
Boonville
10.0 out of 10, Exceptional, (41 reviews)
"Excellent place to stay. Great breakfast and hospitality. Walking distance to restaurants and the cool basement bar at The Fred next door."
United States
MICHAEL
$171 nightly
The price is $194
Mar 16 - Mar 17
Total with taxes and fees
Boonville Luxury Lodging

Holiday Inn Express Boonville by IHG

Holiday Inn Express Boonville by IHG
2.5 star property
Boonville
8.6 out of 10, Excellent, (530 reviews)
"Amenities "
United States
holly
$133 nightly
The price is $149
Apr 5 - Apr 6
Total with taxes and fees
Holiday Inn Express Boonville by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

When is the best time to go to Lupus?
The best time to visit Lupus, Missouri, is during the spring and fall months, specifically from April to early June and from September to October. These periods offer the most pleasant weather for exploring the area.

During spring, the landscape around Lupus comes alive with blooming wildflowers and lush greenery, making it ideal for outdoor activities like hiking and enjoying nature. The temperatures are generally mild, ranging from the 50s to 70s Fahrenheit, which is comfortable for daytime excursions.

Fall brings cooler temperatures and the vibrant colors of autumn foliage, creating a picturesque setting for scenic drives and walks. The weather typically remains dry and comfortable, with temperatures similar to spring.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lupus.
How can I save on a Lupus hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Lupus hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Lupus hotel?
Prices for hotels in Lupus often vary, but you can find a great deal from $64 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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