Lupus Vacations from $423

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The Latest Lupus vacation packages

Price found within the past 48 hours. Click for updated prices.
Finn's 66 Motel

Finn's 66 Motel

2.5 out of 5
Price was $441, price is now $423 per person
$423
per person
Jul 23 - Jul 26
found 1 day ago
Roundtrip flight included
New York (NYC) to Columbia (COU)
8/10 Very Good! (333 reviews)
Found this awesome (older) hotel. Very comfortable & enjoyed our night stay. Bathroom very small - but again older, very well maintained hotel.

Reviewed on Oct 16, 2025

Holiday Inn Express & Suites Kingdom City by IHG

Holiday Inn Express & Suites Kingdom City by IHG

2.5 out of 5
Price was $626, price is now $575 per person
$575
per person
Jun 22 - Jun 24
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Columbia (COU)
9.4/10 Exceptional! (513 reviews)
Clean, friendly staff

Reviewed on Apr 28, 2026

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

2.5 out of 5
Price was $532, price is now $494 per person
$494
per person
Jun 22 - Jun 24
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Columbia (COU)
5.6/10 (397 reviews)
The room was decent. The staff was friendly.

Reviewed on Dec 26, 2025

Capital O Amerihost Inn and Suites Kingdom City Hwy 54 MO

Capital O Amerihost Inn and Suites Kingdom City Hwy 54 MO

2.5 out of 5
Price was $535, price is now $497 per person
$497
per person
Jun 22 - Jun 24
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Columbia (COU)
6.8/10 (358 reviews)
The hotel was located on the outskirts of the area I was visiting and offered a very budget-friendly option, which was exactly what I needed. What really stood out, though, was the customer service. The front desk clerk went out of his way to make sure we were comfortable and had everything we needed throughout our stay. That level of care made a simple, affordable stay feel much more welcoming and appreciated.

Reviewed on Apr 21, 2026

Capital O Amerihost Inn and Suites Fulton Hwy 54 MO

Capital O Amerihost Inn and Suites Fulton Hwy 54 MO

2.5 out of 5
Price was $529, price is now $494 per person
$494
per person
Jun 22 - Jun 24
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Columbia (COU)
5.6/10 (480 reviews)
The modernistic features in the room were a surprise.

Reviewed on May 14, 2026

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Lupus Hotel Deals

Step Back in Time Near The Missouri River

Step Back in Time Near The Missouri River

Jamestown MO
$281 nightly
The price is $298 total per night from Jun 8 to Jun 9
$298 total
Jun 8 - Jun 9
Total with taxes and fees
9.8/10 Exceptional! (19 reviews)
Quaint town. Old house very nicely decorated and clean. We grilled both nights and then sat out on the front porch. Awesome

Reviewed on Apr 13, 2026

Step Back in Time Near The Missouri River
Quiet Riverfront Cottage on Missouri River

Quiet Riverfront Cottage on Missouri River

Jamestown MO
$185 nightly
The price is $197 total per night from Jun 8 to Jun 9
$197 total
Jun 8 - Jun 9
Total with taxes and fees
9/10 Wonderful! (13 reviews)
Birthday getaway
Very cute place. Enjoyed our walk down to the river and watching the water flow

Reviewed on Mar 7, 2025

Quiet Riverfront Cottage on Missouri River
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
Fully refundable
$83 nightly
The price is $93 total per night from Jun 7 to Jun 8
$93 total
Jun 7 - Jun 8
Total with taxes and fees
9/10 Wonderful! (1,834 reviews)
Overall, great experience. Clean rooms, great breakfast and friendly staff.

Reviewed on May 16, 2026

Country Inn & Suites by Radisson, Columbia, MO
See all 261 properties in Lupus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Lupus Vacation Packages

Lupus Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Columbia Regional Airport (COU)

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Frequently asked questions

How much does a Lupus vacation package cost?
Offering great value package deals from $423 on Expedia, you'll be surprised at how little a vacation to Lupus costs! Expedia's packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Lupus?
You can typically find reduced prices and better availability in November, December and January. Take a look at our cheap Lupus vacation packages and you could land some great off-season deals.
How many days is enough for Lupus?
With a well-planned schedule, you can easily visit the main Lupus attractions in a handful of days. But if you prefer to venture off the beaten track or take day trips, consider booking your Lupus vacation for longer.
How to find the best Lupus package deals?
Start your search for a Lupus package deal by entering your destination and preferred travel dates under our "Packages" tab. Then select a few filters, like "Popular locations" and "Property type," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the ideal Lupus package deal straight away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Lupus escape off to a flying start.
Is it cheaper to book a Lupus vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, hotel and flight into one great-value price and enjoy significant savings. You'll usually land a better deal than booking each component separately. And you'll still enjoy the flexibility to create a tailored Lupus vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Lupus?
If you're considering a spur-of-the-moment Lupus getaway, browse our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can find incredible deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Lupus vacation packages?
Set off on your perfect escape to Lupus with our Book Now, Pay Later vacations. There's no need to save up or hold off until payday — we've teamed up with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans mean you can split the cost across 3, 6 or 12 months. With no hidden or late payment fees, it's a breeze to stick to your budget and snap up travel deals before they sell out.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.