Learn a thing or two about those who have lived behind the doors of Palazzo Piccolomini. This impressive residence is noteworthy for its architecture and fascinating history.

Located in Pienza, this historic stately house is well worth including on your itinerary. But you'll find a great deal more to discover in this area. Pienza Cathedral, Piazza Grande, and Consorzio del Vino Nobile di Montepulciano are within close reach of Palazzo Piccolomini.

Plan a trip to see Palazzo Piccolomini

Price found within the past 48 hours. Click for updated prices.

Aurum Uffizi

Historic Centre of Florence

$643

per person

Jan 15 - Jan 20

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Florence (FLR)

7.8/10 Good! (1,015 reviews)

The room was spotless. The staff was helpful and kind. The location was great, though if you are arriving at night, the alley it is in is dark. The pillows were not at all comfortable.

Reviewed on Nov 2, 2025

The Moon Boutique Hotel & Spa

Historic Centre of Florence

Save 100% on your flight

$805

per person

Jan 15 - Jan 20

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Florence (FLR)

9.6/10 Exceptional! (485 reviews)

Great hotel. Good location right across the street from the tram. Very clean and the staff is wonderful.

Reviewed on Nov 1, 2025

Hotel Duomo Firenze

Historic Centre of Florence

$774

per person

Jan 15 - Jan 20

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Florence (FLR)

9/10 Wonderful! (1,006 reviews)

Great location with a great staff

Reviewed on Oct 29, 2025

Browse tours and tickets to explore Palazzo Piccolomini

Tours & day trips

See all 71 activities

From Rome: Tuscany & Montepulciano Day Trip including Lunch & Wine Tasting

Free cancellation available

Private & custom tours

See all 20 activities

Montepulciano: Winery Tour, Tasting, and Vineyard Picnic

Free cancellation available

Wildlife & nature

See all 4 activities

Trequanda: Tuscan Truffle Hunting Experience with Lunch

Free cancellation available

Adventure & outdoor

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Montepulciano Mountain Bike Private Tour

Free cancellation available

Shows & concerts

See all 3 activities

Montepulciano: Tuscan Winery Tour with Wine Tasting & Meal

Free cancellation available

Popular places to visit

Cathedral of Pienza featuring heritage elements, a church or cathedral and religious elements

Pienza Cathedral

Admire the arresting Renaissance façade and the interior Gothic décor of this 15th-century cathedral commissioned by Pope Pius II.

Horti Leonini

Explore the great outdoors at Horti Leonini, a lovely green space in San Quirico d'Orcia. While you're here, you can savor the wineries.

Une superbe petite église dans un vieux village toscan #tuscany#italia

Collegiate Church of San Quirico

After visiting Collegiate Church of San Quirico, make a plan to see the other sights and activities in San Quirico d'Orcia. While you're here, you can savor the wineries.