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Pythagorio Vacation Rentals

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Check prices for these dates

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Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Pythagorio vacation rentals

Seasonal outdoor pool, pool umbrellas, sun loungers
Scorpios Hotel & Suites

Aparthotel in Samos

Scorpios Hotel & Suites
3.0 star property
8.8 out of 10, Excellent, (19)
"It has a very nice view to the ocean and great quality of services "
Mexico
Karla
$93 nightly
The price is $104
Dec 31 - Jan 1, 2026
Total with taxes and fees
Scorpios Hotel & Suites
Beach
Eva's Apartments

Apartment in Karlovasi

Eva's Apartments
$104 nightly
The price is $112
Dec 31 - Jan 1, 2026
Total with taxes and fees
Eva's Apartments
Traditional Villa | Terrace/patio
Villa of the old olive oil factory

Villa in Samos

Villa of the old olive oil factory
8.0 out of 10, Very Good, (6)
"This place has nothing to do with the pictures of this app. Has rotten walls and doors, needs lots of repairing. Besides, it is very dark, tiny and there is an heavy smell inside. The owner even did not bother paying for a name sign. I also put responsibility on hotels.com for providing this option on its portfolio. In short, we unfortunately had to forget about the money we paid and stayed in another place."
Turkey
Ozen
Villa of the old olive oil factory
Private kitchen
THALIA'S COTTAGE

Vacation Home in Samos

THALIA'S COTTAGE
10.0 out of 10, Exceptional, (1)
"Bel emplacement stratégique pour visiter l île. Maison confortable, propre et tranquille.Super hôte Un grand merci "
France
FREDDY B.
$162 nightly
The price is $162
Dec 31 - Jan 1, 2026
Total with taxes and fees
THALIA'S COTTAGE
Beach
Seacret too by Villa Glyfos

Villa in Charavgi

Seacret too by Villa Glyfos
$319 nightly
The price is $319
Jan 5 - Jan 6, 2026
Total with taxes and fees
Seacret too by Villa Glyfos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pythagorio Hotel Reviews

Casa Cook Samos

Casa Cook Samos

10/10 Excellent
"Clean and modernly decorated rooms with all the facilities"
Aylin 3-night trip
Posted 2 months ago
Casa Cook Samos

Find out more about Pythagorio

Everything you need to know about Pythagorio vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Pythagorio vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Pythagorio vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Pythagorio vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Pythagorio. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Pythagorio in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $104 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Pythagorio rentals

At Expedia, we put the best Pythagorio vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Pythagorio rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Pythagorio vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Pythagorio. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Pythagorio?

Yes, we give you a choice of vacation rentals near well known points of interest in Pythagorio, or you can go with a more secluded option if you're looking for relaxation. Discover why Pythagorio is known for its waterfront and seaside. Make sure you have time to check out the monuments and museums during your trip.

What are some of the best vacation rentals that Pythagorio has to offer?

Astonishing house with sea view in Samos Island: Located near Pythagorio, this vacation home rental offers a balcony, a garden, and cable TV to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, an oven, and a coffee maker.

How many vacation rentals will I find in Pythagorio?

With 5 Expedia vacation rentals, you're sure to find just the right place for your Pythagorio stay.

What can I see and do in Pythagorio?

Enjoy the outdoors at Glicorisa Beach and Potakaki beach, or simply take in cultural attractions like Folklore Museum of Samos and Nikolaos Dimitriou Folklore Museum. Other places in town to visit include Samos Pythagorion Archaeological Museum and Pythagoreion.

What are vacation rentals like in Pythagorio?

Vacation rentals are privately owned properties you can stay in for a short or long stay in Pythagorio. Vacation rentals feature amenities such as kitchens and laundry facilities so you'll have all the comforts of home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from shared hotel elevators and busy front desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental a popular choice for families.