Mainz City Center Vacations from $873

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Mainz City Center Vacation

Book a Mainz City Center vacation package that includes only the things you need and nothing you don't. Good for culture, bars and pubs and history, consider basing yourself in the neighborhood of Neustadt. A trip to Mainz City Center is a superb opportunity to take in the sights. Be sure to visit renowned attractions like Mainz Cathedral, Gutenberg Museum and Mewa Arena. Whatever your travel plans or the size of your budget, organizing your ultimate tailored Mainz City Center vacation is a breeze with Expedia.

The Latest Mainz City Center Vacation Packages

Price found within the past 48 hours. Click for updated prices.
City Hotel Frankfurt am Main Bad Vilbel

City Hotel Frankfurt am Main Bad Vilbel

$873
per person
Nov 6 - Nov 11
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Frankfurt (FRA)
8.4/10 Very Good! (628 reviews)
Personal freundlich, Zimmer sauber aber Betten unbequem, Restaurant preislich fair, allerdings nicht besonders schmackhaft

Reviewed on Feb 16, 2026

Villa Westend Hotel an der Messe

Villa Westend Hotel an der Messe

Westend-Süd
$1,578
per person
Oct 3 - Oct 9
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Frankfurt (FRA)
8.2/10 Very Good! (196 reviews)
Very nice hotel . Room was spacious , breakfast was delicious and staff very attentive . Only a short walk from main station and old town

Reviewed on Aug 23, 2026

The Blasky Frankfurt

The Blasky Frankfurt

Frankfurt am Main Süd
$1,286
per person
Oct 3 - Oct 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Frankfurt (FRA)
8.8/10 Excellent! (345 reviews)
Concorde Hotel Viktoria

Concorde Hotel Viktoria

$1,070
per person
Nov 14 - Nov 18
found 2 days ago
Roundtrip flight included
New York (NYC) to Frankfurt (FRA)
9/10 Wonderful! (71 reviews)
It was perfect

Reviewed on Jun 28, 2026

Leinsweiler Hof

Leinsweiler Hof

$2,109
per person
Oct 18 - Oct 24
found 13 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Frankfurt (FRA)
9/10 Wonderful! (31 reviews)
Hotel sehr gut gemanagt. Perfekter Ablauf

Reviewed on Jul 1, 2026

Where to stay in Mainz City Center

Find the best Mainz City Center areas and neighborhoods for the activities you enjoy most. Learn more about Mainz City Center
A cobblestone street lined with traditional half-timbered buildings, a clear blue sky, and a few pedestrians.

Altstadt Mainz

You'll enjoy the museums and churches in Altstadt Mainz. You might want to make time for a stop at Mainz Cathedral or Gutenberg Museum.

A panoramic view of a city with a prominent church, dense urban area, and surrounding greenery.

Oberstadt

1 out of top 10 points of interest in this area

Travelers enjoy Oberstadt for its coffeehouses and spas. Consider checking out St. Achatius while you're in the area.

A pathway flanked by stone structures and trees.

Bretzenheim

1 out of top 10 points of interest in this area

Unique features of Bretzenheim include the restaurants and shopping. Make a stop by Mewa Arena or St. Achatius while you're exploring the area.

A cityscape with a prominent church tower, industrial chimneys, and a statue in the foreground.

Hartenberg-Münchfeld

Restaurants and historic sites are notable features of Hartenberg-Münchfeld. You might consider a stop by St. Achatius while you're exploring the neighborhood.

A fountain with water jets in a park.

Neustadt

1 out of top 10 points of interest in this area

You might enjoy the river views while in Neustadt. Zollhafen Mainz is a notable sight, and you can get around town at Mainz Central Station Tram Stop or Mainz Hauptbahnhof West/Taubertsbergbad Tram Stop to see more of the city.

Mainz City Center Hotel Deals

IntercityHotel Mainz

IntercityHotel Mainz

Binger Strasse 21 Mainz RP
Fully refundableReserve now, pay when you stay
$87 nightly
$102 total
Sep 27 - Sep 28
Total with taxes and fees
8.4/10 Very Good! (1,001 reviews)
"The man working at the check in was really lovely and helpful and even printed me papers, that i forgot to do at home, within seconds. Thank you very much ;)"

Reviewed on Aug 16, 2026

IntercityHotel Mainz
Hyatt Regency Mainz

Hyatt Regency Mainz

Templerstraße 6 Mainz
Fully refundableReserve now, pay when you stay
$151 nightly
$173 total
Sep 6 - Sep 7
Total with taxes and fees
9.4/10 Exceptional! (806 reviews)
"The location, elevators, staff, and parking situation were fantastic!"

Reviewed on Aug 28, 2026

Hyatt Regency Mainz
Sheraton Frankfurt Airport Hotel & Conference Center

Sheraton Frankfurt Airport Hotel & Conference Center

Flughafen Terminal 1 Frankfurt HE
Fully refundableReserve now, pay when you stay
$176 nightly
$193 total
Sep 27 - Sep 28
Total with taxes and fees
8.8/10 Excellent! (3,190 reviews)
"Good bar selection."

Reviewed on Aug 31, 2026

Sheraton Frankfurt Airport Hotel & Conference Center
See all 1,337 properties in Mainz City Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mainz City Center attractions

A historic town square at dusk with a prominent church tower, reflecting buildings, and a reflective water feature.

Mainz Cathedral

8.8/10 (315 reviews)
Beneath its six soaring towers, immerse yourself in over a millennium’s worth of history at the city’s opulent sandstone cathedral.
See properties
A cobblestone street lined with historic buildings, a bicycle, and people walking.

Augustinerstrasse

9.0/10 (101 reviews)
Stroll through Mainz’s Old Town along this pedestrianized street, lined with shopping boutiques and a remarkably preserved assortment of colorful historic buildings.
See properties
A modern building with a glass facade and a bronze plaque wall.

Gutenberg Museum

8.6/10 (170 reviews)
In the heart of Mainz’s Old Town, trace the history of bookmaking and discover how the city served as the birthplace of modern printing.
See properties
A narrow street lined with traditional half-timbered houses, a prominent tower, and a clear blue sky.

Kirschgarten

9.0/10 (19 reviews)
Discover Mainz at its most charming in this romantic square, bordered by historic half-timbered homes and anchored by a bubbling Baroque-style fountain.
See properties

Rheingoldhalle

8.0/10 (56 reviews)
After visiting Rheingoldhalle, make a plan to see the other sights and activities in Mainz. Experience the area's museums and festivals.
See properties

Church of St. Stephan

10.0/10 (4 reviews)
After visiting Church of St. Stephan, make a plan to see the other sights and activities in Mainz. Discover the area's museums and cathedral.
See properties

Landesmuseum Mainz

6.0/10 (1 review)
You can browse the exhibits at Landesmuseum Mainz, a museum with a storied past, during your trip to Mainz. Discover the area's museums and cathedral.
See properties

Electoral Palace

8.6/10 (22 reviews)
After visiting Electoral Palace, make a plan to see the other sights and activities in Mainz. Discover the area's museums and cathedral.
See properties

Things to do

Mainz Old Town: A Self-Guided Walking Tour

Mainz Old Town: A Self-Guided Walking Tour

$9
per adult
Mainz Old Town: A Self-Guided Walking Tour
Wiesbaden: Naturally Wiesbaden - public tour

Wiesbaden: Naturally Wiesbaden - public tour

$26
per adult
Wiesbaden: Naturally Wiesbaden - public tour
Fun and uncomplicated tastings!

Exclusive Wine & Food Tasting in Historic Cellar | Mainz Old Town

$99
per adult
Exclusive Wine & Food Tasting in Historic Cellar | Mainz Old Town
See all activities in Mainz

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.