Mainz City Center Vacations from $1,107

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Your Mainz City Center Vacation

Book a Mainz City Center vacation package that includes only the things you need and nothing you don't. Good for culture, bars and pubs and history, consider basing yourself in the neighborhood of Neustadt. A trip to Mainz City Center is a superb opportunity to take in the sights. Be sure to visit renowned attractions like Mainz Cathedral, Gutenberg Museum and Mewa Arena. Whatever your travel plans or the size of your budget, organizing your ultimate tailored Mainz City Center vacation is a breeze with Expedia.

The Latest Mainz City Center Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Sunday am Main Taunus Zentrum Frankfurt/Sulzbach

Sunday am Main Taunus Zentrum Frankfurt/Sulzbach

$1,107
per person
Dec 1 - Dec 7
found 1 day ago
Roundtrip flight included
Washington (IAD) to Frankfurt (FRA)
8.2/10 Very Good! (1,002 reviews)
Amazing hotel.

Reviewed on Oct 13, 2026

Villa Westend Hotel an der Messe

Villa Westend Hotel an der Messe

Westend-Süd
$1,143
per person
Nov 29 - Dec 5
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Frankfurt (FRA)
8.2/10 Very Good! (200 reviews)
I was very happy to find this boutique hotel within shouting distance of the Messe. For many years I stayed at the Marriott but wanted a change. It is a charming, quiet and comfortable hotel. The staff are particularly good natured and helpful. I hope no one reads this review so the rates don’t go up too much for next year. Be aware though it’s not fancy or upscale so if that is what you are after it may not be the right fit for you.

Reviewed on Oct 9, 2026

Hotel Monopol

Hotel Monopol

Gutleutviertel
$1,206
per person
Nov 29 - Dec 5
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Frankfurt (FRA)
8.2/10 Very Good! (1,003 reviews)
Location is close to train station but in a sketchy area. Room had bed bugs. We were given another room which also had bed bugs and were not comfotable staying at this property, we had to find another hotel at 2am. Staff was helpful but couldn’t speak english which made it difficult during the situation. We did receive a refund from the hotel as expedia pushed for one. Would not recommend staying here

Reviewed on Oct 21, 2026

Hofgut Georgenthal

Hofgut Georgenthal

$1,592
per person
Dec 1 - Dec 7
found 1 day ago
Roundtrip flight included
Washington (IAD) to Frankfurt (FRA)
9/10 Wonderful! (99 reviews)
It is a very nice place to rest and relax. Although this hotel may not be the most family-oriented option for guests with small children, we had a very pleasant stay. We visited for the weekend with our two year old daughter, and the staff was very kind, helpful, and attentive to all our requests. We truly appreciated their hospitality. Only a very small downside was that the bed was not the very comfortable I would expect in this hotel. Apart from that, we will certainly come back again :)

Reviewed on May 8, 2026

City Hotel Frankfurt am Main Bad Vilbel

City Hotel Frankfurt am Main Bad Vilbel

$1,306
per person
Jan 10 - Jan 16
found 1 hour ago
Roundtrip non-stop flight included
New York (LGA) to Frankfurt (FRA)
8.4/10 Very Good! (635 reviews)
Very helpful staff All great thank you

Reviewed on Sep 15, 2026

Where to stay in Mainz City Center

Find the best Mainz City Center areas and neighborhoods for the activities you enjoy most. Learn more about Mainz City Center
A panoramic view of a city with a prominent church, dense urban area, and surrounding greenery.

Oberstadt

1 out of top 10 points of interest in this area

Travelers enjoy Oberstadt for its coffeehouses and spas. Consider checking out St. Achatius while you're in the area.

A cobblestone street lined with traditional half-timbered buildings, a clear blue sky, and a few pedestrians.

Altstadt Mainz

You'll enjoy the museums and churches in Altstadt Mainz. You might want to make time for a stop at Mainz State Theater or Mainz Cathedral.

A pathway flanked by stone structures and trees.

Bretzenheim

1 out of top 10 points of interest in this area

Unique features of Bretzenheim include the restaurants and shopping. Make a stop by Mewa Arena or St. Achatius while you're exploring the area.

A historic building with multiple towers and a large clock tower, illuminated at night.

Neustadt

1 out of top 10 points of interest in this area

You might enjoy the river views while in Neustadt. Zollhafen Mainz is a notable sight, and you can get around town at Mainz Central Station Tram Stop or Mainz Hauptbahnhof West/Taubertsbergbad Tram Stop to see more of the city.

A cityscape with a prominent church tower, industrial chimneys, and a statue in the foreground.

Hartenberg-Münchfeld

Restaurants and historic sites are notable features of Hartenberg-Münchfeld. You might consider a stop by St. Achatius while you're exploring the neighborhood.

Mainz City Center Hotel Deals

Hyatt Regency Mainz

Hyatt Regency Mainz

Templerstraße 6 Mainz
Fully refundableReserve now, pay when you stay
$121 nightly
$141 total
Nov 15 - Nov 16
Total with taxes and fees
9.4/10 Exceptional! (816 reviews)
"The breakfast was fabulous. Also enjoyed having dinner on two separate nights in hotel restaurant."

Reviewed on Oct 16, 2026

Hyatt Regency Mainz
Sheraton Frankfurt Airport Hotel & Conference Center

Sheraton Frankfurt Airport Hotel & Conference Center

Flughafen Terminal 1 Frankfurt HE
Fully refundableReserve now, pay when you stay
$143 nightly
$158 total
Nov 8 - Nov 9
Total with taxes and fees
8.8/10 Excellent! (3,335 reviews)
"Very convenient, walking distance from the Terminal. Excellent facility at a very good price!"

Reviewed on Oct 26, 2026

Sheraton Frankfurt Airport Hotel & Conference Center
Scandic Frankfurt Museumsufer

Scandic Frankfurt Museumsufer

Wilhelm-Leuschner-Straße 44 Frankfurt HE
Fully refundable
$113 nightly
$125 total
Nov 14 - Nov 15
Total with taxes and fees
9/10 Wonderful! (1,306 reviews)
"It was nice"

Reviewed on Oct 24, 2026

Scandic Frankfurt Museumsufer
See all 1,347 properties in Mainz City Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mainz City Center attractions

A historic town square at dusk with a prominent church tower, reflecting buildings, and a reflective water feature.

Mainz Cathedral

8.8/10 (315 reviews)
Beneath its six soaring towers, immerse yourself in over a millennium’s worth of history at the city’s opulent sandstone cathedral.
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A cobblestone street lined with historic buildings and flower-adorned lampposts.

Augustinerstrasse

9.0/10 (101 reviews)
Stroll through Mainz’s Old Town along this pedestrianized street, lined with shopping boutiques and a remarkably preserved assortment of colorful historic buildings.
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A modern building with a glass facade and a bronze plaque wall.

Gutenberg Museum

8.6/10 (170 reviews)
In the heart of Mainz’s Old Town, trace the history of bookmaking and discover how the city served as the birthplace of modern printing.
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A narrow street lined with traditional half-timbered houses, a prominent tower, and a clear blue sky.

Kirschgarten

9.0/10 (19 reviews)
Discover Mainz at its most charming in this romantic square, bordered by historic half-timbered homes and anchored by a bubbling Baroque-style fountain.
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Rheingoldhalle

8.0/10 (56 reviews)
After visiting Rheingoldhalle, make a plan to see the other sights and activities in Mainz. Experience the area's museums and festivals.
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Mainz State Theater

8.0/10 (22 reviews)
Enjoy a performance at Mainz State Theater, a theater with a story to tell in Mainz. Experience the area's museums and festivals.
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Electoral Palace

8.6/10 (22 reviews)
After visiting Electoral Palace, make a plan to see the other sights and activities in Mainz. Discover the area's museums and cathedral.
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Church of St. Stephan

10.0/10 (4 reviews)
After visiting Church of St. Stephan, make a plan to see the other sights and activities in Mainz. Discover the area's museums and cathedral.
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Things to do

Mainz Old Town: A Self-Guided Walking Tour

Mainz Old Town: A Self-Guided Walking Tour

$9
per adult
Mainz Old Town: A Self-Guided Walking Tour
Mainz Lost Relic Self Guided Walking Tour and Treasure Hunt

Mainz Lost Relic Self Guided Walking Tour and Treasure Hunt

$10
per adult
Mainz Lost Relic Self Guided Walking Tour and Treasure Hunt
Wiesbaden: City whispers

Wiesbaden: City whispers

$22
per adult
Wiesbaden: City whispers
See all activities in Mainz

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