Santa Cruz de la Sierra Vacations from $618

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The Latest Santa Cruz de la Sierra vacation packages

Price found within the past 48 hours. Click for updated prices.
B&B HOTEL Madrid Arganda

B&B HOTEL Madrid Arganda

3 out of 5
per person
Sep 9 - Sep 16
found 1 day ago
Roundtrip flight included
New York (JFK) to Madrid (MAD)
9/10 Wonderful! (14 reviews)
Staff was friendly but there is not much to do around the hotel.

Reviewed on Apr 14, 2025

Hostal Alfaro

Hostal Alfaro

2 out of 5
Madrid Centro
per person
Sep 9 - Sep 16
found 1 day ago
Roundtrip flight included
New York (JFK) to Madrid (MAD)
9/10 Wonderful! (161 reviews)
First time staying in a Hostal (private room a bath). Enjoyed the staffs helpfulness. Would definitely recommend this location to others and stay again.

Reviewed on Jul 19, 2025

Hotel Gran Versalles

Hotel Gran Versalles

4 out of 5
Chamberí
per person
Sep 9 - Sep 16
found 1 day ago
Roundtrip flight included
New York (JFK) to Madrid (MAD)
8.8/10 Excellent! (1,002 reviews)
Room, lobby and location

Reviewed on Jul 16, 2025

Petit Hostel La Latina - Adults Only

Petit Hostel La Latina - Adults Only

2 out of 5
Arganzuela
Save 100% on your flight
per person
Oct 3 - Oct 8
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Madrid (MAD)
8.2/10 Very Good! (133 reviews)
I’ve stayed here for a week. The staff was a great

Reviewed on May 30, 2025

Hotel Riu Plaza España

Hotel Riu Plaza España

4 out of 5
Madrid Centro
Save 100% on your flight
per person
Oct 16 - Oct 21
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
9.4/10 Exceptional! (4,194 reviews)
Our stay was extremely comfortable. The staff supper attentive and kind. Breakfast was amazing!

Reviewed on Jul 22, 2025

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Santa Cruz de la Sierra Hotel Deals

Rural house (full rental) El Olivar del Marqués for 26 people

Rural house (full rental) El Olivar del Marqués for 26 people

Santa Cruz de la Sierra
10/10 Exceptional! (3 reviews)
Estupendo
"Estuvimos muy cómodos, la casa ideal para una quedada damiliar y la ubicacion perfecta para visitar Trujillo. Adrián, el anfitrión, atento en todo momento. Repetiremos!"

Reviewed on Oct 6, 2022

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Rural house (full rental) El Olivar del Marqués for 26 people
The House of Luis for 4 people

The House of Luis for 4 people

Santa Cruz de la Sierra
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The House of Luis for 4 people
The House of Luis for 2 people

The House of Luis for 2 people

Santa Cruz de la Sierra
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The House of Luis for 2 people
See all 86 properties in Santa Cruz de la Sierra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Cruz de la Sierra Vacation Packages

Santa Cruz de la Sierra Essential Information

Language
Spanish
Currency
Euros
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
310
Max Temp Winter
55ºF
Max Temp Summer
90ºF
Top Sights
Trujillo Castle, Juan Pizarro de Orellana Palace and Palace of the Marquis of the Conquest

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Frequently asked questions

How much does a Santa Cruz de la Sierra vacation package cost?
You can snap up a vacation package to this top destination from $618 on Expedia. However, how much your vacation to Santa Cruz de la Sierra costs will depend on factors like your hotel choice, season and length of stay.
What are the cheapest months to go to Santa Cruz de la Sierra?
February, November and December are great times to look for cheap Santa Cruz de la Sierra vacation packages. Opting to travel in quieter months means you'll typically find reduced prices on flights and hotels.
How many days is enough for Santa Cruz de la Sierra?
The ideal length of your Santa Cruz de la Sierra vacation depends on what you'd like to do and see. Generally, a handful of days to a week will give you plenty of time to go to all the leading sights and explore some hidden spots along the way.
How to find the best Santa Cruz de la Sierra package deals?
Use Expedia's filters to find some of the best Santa Cruz de la Sierra package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or search for Santa Cruz de la Sierra package deals in the low season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package as soon as possible.
Is it cheaper to book a Santa Cruz de la Sierra vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging hotels and flights separately. Better still, you can customize your Santa Cruz de la Sierra getaway to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Santa Cruz de la Sierra?
If you're planning a spontaneous Santa Cruz de la Sierra getaway, browse our last-minute deals that can be booked up to one week before you take off. Don't want to leave things to the last minute? You can find incredible deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Santa Cruz de la Sierra vacation packages?
If you're like us, you love going away but don't love the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Santa Cruz de la Sierra vacation across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.