Default HTG hotel image

Santa Cruz Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Nov 20 - Nov 22
In two months
Jan 1 - Jan 3
In three months
Jan 29 - Jan 31
In four months
Feb 26 - Feb 28

Our top choices for Santa Cruz vacation rentals

A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

1. A30 Plaza Acequia Suite Black Plus

A30 Plaza Acequia Suite Black Plus
3.5 star property
Cuautitlán Izcalli
10.0 out of 10, Exceptional, (1 review)
"Todo un ambiente acogedor"
Mexico
GENER KEINER
$80 nightly
The price is $97
Nov 5 - Nov 6
Total with taxes and fees
A30 Plaza Acequia Suite Black Plus
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

2. A21 Full Suite MiniDept at Plaza Acequia

A21 Full Suite MiniDept at Plaza Acequia
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
$71 nightly
The price is $85
Nov 30 - Dec 1
Total with taxes and fees
A21 Full Suite MiniDept at Plaza Acequia
A balcony with two chairs, a small table with a book and a cup, and a view of the cityscape.

3. S06 PREMIUM SUITE Full Service WiFi Kitc

S06 PREMIUM SUITE Full Service WiFi Kitc
3.5 star property
Ciudad López Mateos
9.8 out of 10, Exceptional, (6 reviews)
"Estuvo super bien nuestra estancia "
Mexico
Sophie
$68 nightly
The price is $81
Nov 5 - Nov 6
Total with taxes and fees
S06 PREMIUM SUITE Full Service WiFi Kitc
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

4. A08 SUPER CITY SUITES AT PLAZA ACEQUIA

A08 SUPER CITY SUITES AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
8.0 out of 10, Very good, (4 reviews)
"No dejan dormir pasaron algunos huéspedes ablandó fuerte y caminando por los corredores y nadie les llamó la atención. Según parecía estaban borrachos"
United States
Mario
$71 nightly
The price is $85
Nov 10 - Nov 11
Total with taxes and fees
A08 SUPER CITY SUITES AT PLAZA ACEQUIA
Living area

5. Lofts by Verticca San Francisco

Lofts by Verticca San Francisco
3.5 star property
Ojo de Agua
8.6 out of 10, Excellent, (46 reviews)
"Nice place! "
Canada
erick
$50 nightly
The price is $61
Nov 10 - Nov 11
Total with taxes and fees
Lofts by Verticca San Francisco
A hotel entrance with a glass door and a sign displaying greetings in multiple languages.

6. A11 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A11 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
$88 nightly
The price is $105
Dec 3 - Dec 4
Total with taxes and fees
A11 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A compact kitchen with a built-in microwave, a gas stove, and a dishwasher.

7. Moderna, Comoda Suite Palma en Tepotzotlán centro

Moderna, Comoda Suite Palma en Tepotzotlán centro
3.0 star property
Tepotzotlán
10.0 out of 10, Exceptional, (3 reviews)
"Friendly host who was very helpful in recommending things to do and places to eat. Located just a few blocks from the historical district. On your way there, you'll pass wonderful restaurants, coffee shops, gyms, and convient stores. This place is in a great location and having garage parking was a real plus. Absolutely a beautiful room and very clean. I was very impressed and highly recommend staying here."
United States
Nathan
$62 nightly
The price is $75
Nov 10 - Nov 11
Total with taxes and fees
Moderna, Comoda Suite Palma en Tepotzotlán centro
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

8. A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (2 reviews)
"Lo único que me disgusta es que no hay agua caliente )): Pero sin duda iré todos los 12 de cada mes "
Mexico
Jeik
$71 nightly
The price is $85
Nov 21 - Nov 22
Total with taxes and fees
A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A compact kitchen with a wooden cabinet, a sink, and a countertop. There are kitchen utensils and a coffee maker on the counter.

9. S02 FULL SUITE ITESM CEM WiFi Terraza

S02 FULL SUITE ITESM CEM WiFi Terraza
3.5 star property
Ciudad López Mateos
10.0 out of 10, Exceptional, (1 review)
"Muy limpio Agradable la señorita de limpieza"
Mexico
Mauricio
$71 nightly
The price is $85
Nov 5 - Nov 6
Total with taxes and fees
S02 FULL SUITE ITESM CEM WiFi Terraza
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

10. A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
9.4 out of 10, Exceptional, (3 reviews)
"Buenas instalaciones y ubicación para mis desplazamientos"
Mexico
ANGEL
$71 nightly
The price is $85
Nov 5 - Nov 6
Total with taxes and fees
A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

11. A07 SUPER CITY SUITES AT PLAZA ACEQUIA

A07 SUPER CITY SUITES AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (2 reviews)
"Buen lugar tranquilo "
Mexico
Valeria
$51 nightly
The price is $61
Dec 3 - Dec 4
Total with taxes and fees
A07 SUPER CITY SUITES AT PLAZA ACEQUIA
Balcony

12. S09 PREMIUM SUITE Full Service WiFi

S09 PREMIUM SUITE Full Service WiFi
3.5 star property
Ciudad López Mateos
9.6 out of 10, Exceptional, (4 reviews)
"Excelente"
United States
Yulissa Rubi
$68 nightly
The price is $81
Nov 11 - Nov 12
Total with taxes and fees
S09 PREMIUM SUITE Full Service WiFi
A compact kitchen with a built-in microwave, a coffee maker, and a sink. A flat-screen TV is mounted on the wall, displaying a menu interface.

13. A01 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A01 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
$66 nightly
The price is $80
Dec 3 - Dec 4
Total with taxes and fees
A01 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A courtyard with a checkered floor, a covered seating area with a railing, and potted plants.

14. Casa Chopo

Casa Chopo
3.5 star property
Cuauhtémoc
9.4 out of 10, Exceptional, (158 reviews)
"very friendly staffs"
United States
Pengfei
$42 nightly
The price is $50
Nov 11 - Nov 12
Total with taxes and fees
Casa Chopo
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

15. A25 Full Suite MiniDept at Plaza Acequia

A25 Full Suite MiniDept at Plaza Acequia
3.0 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
$84 nightly
The price is $100
Dec 3 - Dec 4
Total with taxes and fees
A25 Full Suite MiniDept at Plaza Acequia
A palm tree in front of a building with arched windows and a brick facade.

16. cabañas en arcos del sitio

cabañas en arcos del sitio
3.0 star property
Nicolás Romero
$143 nightly
The price is $172
Nov 5 - Nov 6
Total with taxes and fees
cabañas en arcos del sitio
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

17. A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
$65 nightly
The price is $78
Dec 3 - Dec 4
Total with taxes and fees
A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

18. A13 SUPER CITY SUITE PLAZA ACEQUIA

A13 SUPER CITY SUITE PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
"Buen servicio "
Mexico
Ruben
$71 nightly
The price is $85
Dec 3 - Dec 4
Total with taxes and fees
A13 SUPER CITY SUITE PLAZA ACEQUIA
A balcony with a blue chair, a table with a book, a water bottle, and a potted plant.

19. S08 PREMIUM SUITE Full Service WiFi

S08 PREMIUM SUITE Full Service WiFi
3.5 star property
Ciudad López Mateos
$64 nightly
The price is $76
Nov 5 - Nov 6
Total with taxes and fees
S08 PREMIUM SUITE Full Service WiFi
A modern outdoor dining area with a table set for breakfast, surrounded by potted plants and a view of the building's interior.

20. ULIV Parque Lincoln

ULIV Parque Lincoln
3.5 star property
Polanco
9.6 out of 10, Exceptional, (1,283 reviews)
"Excellent stay, best location"
United States
Alicia Elena
$161 nightly
The price is $192
Nov 7 - Nov 8
Total with taxes and fees
ULIV Parque Lincoln
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Hotel Parque Satelite

Hotel Parque Satelite

10/10 Excellent
"Lugar bonito, cómodo, céntrico 10/10, el lugar es más bonito que en las fotos."
Feliza 3-night trip
Posted 2 hours ago
Hotel Parque Satelite

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $45 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Santa Cruz?

Yes, you can find vacation rentals near popular points of interest in Santa Cruz, or you can go with a secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Cruz?

Luxe Polanco Home Private Yard and Private Patio: This vacation home rental near Santa Cruz offers a garden, a selection of games, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 7 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

What’s there to see and do in Santa Cruz?

Explore the area and family-friendly sights such as Parque Acuatico Vito Spa, or get out into nature at a spot like Hacienda La Concepcion. Temple of San Francisco Javier and National Museum of the Viceroyalty are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties you can book for a long or short time in Santa Cruz. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for family trips.