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Our top choices for Santa Rosa hotels

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.0 out of 10, Wonderful, (1,002 reviews)
"The stay was amazing"
United States
Desmond
$101 nightly
The price is $111
Jul 4 - Jul 5
Total with taxes and fees
Courtyard by Marriott Panama Metromall

Arcadia Condo Suites

Arcadia Condo Suites
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (309 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
$140 nightly
The price is $154
Jul 6 - Jul 7
Total with taxes and fees
Arcadia Condo Suites

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (706 reviews)
"Stunning ! Beautiful Hotel ! Excelent Service Delicious Food Luxury modern room Can’t wait to go back ! Love it so much !"
United States
Marina
$260 nightly
The price is $286
Jul 9 - Jul 10
Total with taxes and fees
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The District Hotel Panama

The District Hotel Panama
3.0 star property
Bella Vista
8.4 out of 10, Very Good, (5 reviews)
"The rooms are clean, the bed was very comfortable. They have been updating the rooms to include new beds. Breakfast is served on time, and is mostly Panamanian cuisine. They staff is very helpful. The area is walkable with stores and restaurants nearby. I would stay again."
United States
Terry
$65 nightly
The price is $72
Jun 28 - Jun 29
Total with taxes and fees
The District Hotel Panama

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (235 reviews)
"Breakfast was very good, staff are very helpful and friendly "
United States
Farah
$127 nightly
The price is $140
Jul 4 - Jul 5
Total with taxes and fees
Renaissance Panama City Hotel

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,004 reviews)
"Solid property with excellent staff."
United States
Craig
$135 nightly
The price is $149
Jul 4 - Jul 5
Total with taxes and fees
Sheraton Grand Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,646 reviews)
"Great Location, good food."
United States
Yohan
$132 nightly
The price is $145
Jun 30 - Jul 1
Total with taxes and fees
Hotel Riu Plaza Panama

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (335 reviews)
"Amazing area and hotel"
United States
Kendall
$231 nightly
The price is $254
Jul 11 - Jul 12
Total with taxes and fees
The Westin Panama

Serenade Lodging Rooms

Serenade Lodging Rooms
3.0 star property
San Francisco
8.2 out of 10, Very Good, (26 reviews)
"Nice affordable place. "
United States
Sandor
$53 nightly
The price is $59
Jun 28 - Jun 29
Total with taxes and fees
Serenade Lodging Rooms

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,003 reviews)
"The breakfast was very good. We love staying here"
United States
Patricia
$86 nightly
The price is $94
Jul 4 - Jul 5
Total with taxes and fees
Radisson Hotel Panama Canal

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,001 reviews)
"Great hotel. Highly recommend"
United States
Robert
$271 nightly
The price is $298
Jul 11 - Jul 12
Total with taxes and fees
JW Marriott Panama

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (351 reviews)
"Great stay! We enjoyed the hospitality!"
United States
Craig
$220 nightly
The price is $242
Jul 3 - Jul 4
Total with taxes and fees
Hyatt Regency Panama City

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (981 reviews)
"I would stay here again rooms where very clean"
United States
nicole
$109 nightly
The price is $120
Jun 28 - Jun 29
Total with taxes and fees
Waymore Hotel Spa & Casino

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1,573 reviews)
"I love my stay, very convenient for everything, shopping, close by red bus stop and airport!!!"
United States
Carla
$128 nightly
The price is $141
Jul 26 - Jul 27
Total with taxes and fees
Megapolis Hotel Panamá

The Executive Hotel

The Executive Hotel
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1,160 reviews)
"Perfect location."
Canada
Aimee Patricia Feliz
$89 nightly
The price is $98
Jul 23 - Jul 24
Total with taxes and fees
The Executive Hotel

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1,007 reviews)
"Our stay was great ! Definitely worth staying here 👍"
United States
CODY
$170 nightly
The price is $187
Jul 19 - Jul 20
Total with taxes and fees
Central Hotel Panama Casco Viejo

Hotel San Felipe

Hotel San Felipe
4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (404 reviews)
$147 nightly
The price is $162
Jul 2 - Jul 3
Total with taxes and fees
Hotel San Felipe

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,178 reviews)
"One of my favorite hotels in Panama City, always a great experience and lots of things to do close by, the best breakfast buffet in the area."
United States
Danny
$103 nightly
The price is $114
Jul 16 - Jul 17
Total with taxes and fees
Plaza Paitilla Inn Hotel

Magnolia Inn

Magnolia Inn
2.0 star property
Casco Viejo
8.8 out of 10, Excellent, (478 reviews)
"Decent for a 2 night stay"
United States
Alejandra
$73 nightly
The price is $80
Jun 29 - Jun 30
Total with taxes and fees
Magnolia Inn

Hotel Bardot Boutique

Hotel Bardot Boutique
3.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (34 reviews)
"Extraordinary location, nice decor, very kind and helpful staff, delicious breakfast and good dinner / bar option. "
Brazil
Gabriela
$105 nightly
The price is $116
Jul 6 - Jul 7
Total with taxes and fees
Hotel Bardot Boutique
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Frequently asked questions

What is the best area to stay in Santa Rosa?
The best area to stay in Santa Rosa for most travelers is the city center, particularly around Avenida Central and the Parque Central.

This area is the heart of Santa Rosa, offering a convenient base for exploring the city. You'll find a concentration of local businesses, dining options, and access to public transportation. The Parque Central is a key landmark, providing a central gathering spot.

For travelers who appreciate convenience and easy access to local amenities, staying in the city center is ideal.
When is the best time to go to Santa Rosa?
The best time to visit Santa Rosa, Colón, Panama, is during the dry season, which runs from mid-December to mid-April. This period offers the most comfortable weather for exploring.

During these months, you'll experience sunny days with lower humidity and minimal rainfall, making it ideal for outdoor activities like hiking, wildlife viewing, and enjoying the beaches. The clearer skies also provide better conditions for photography and sightseeing.

Travelers looking for a relaxed and pleasant experience will find this time particularly suitable.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Rosa.
How can I save on a Santa Rosa hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santa Rosa hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Rosa hotel?
Prices for hotels in Santa Rosa often vary, but you can find a great deal from $22 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.