Title: Top 10 Hotels in Santa Rosa from $22 - Competitive Prices | Expedia.com [Santa Rosa Travel Guide](https://expedia.com/Santa-Rosa.dx829297946878021632)[Vacation Rentals in Santa Rosa](https://expedia.com/Santa-Rosa-Vacation-Rentals.d829297946878021632.Travel-Guide-VacationRentals)[Flights to Santa Rosa](https://expedia.com/Cheap-Flights-To-Santa-Rosa.d829297946878021632.Travel-Guide-Flights)[Car Rentals in Santa Rosa](https://expedia.com/Car-Rentals-In-Santa-Rosa.d829297946878021632.Car-Rental-Guide)[Santa Rosa Vacation Packages](https://expedia.com/Santa-Rosa.d829297946878021632.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Rosa Family friendly [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&travelerType=family_friendly) Pool [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&amenities=POOL) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&amenities=PETS) Spa [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&amenities=SPA_ON_SITE) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&amenities=HOT_TUB) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&lodging=APARTMENT) Condo [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-04-11&d1=2026-04-11&endDate=2026-04-13&d2=2026-04-13&lodging=CONDO) ## Check prices for these dates Tonight [Mar 28 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=829297946878021632&startDate=2026-03-28&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 29 - Mar 30](https://www.expedia.com/Hotel-Search?regionId=829297946878021632&startDate=2026-03-29&endDate=2026-03-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=829297946878021632&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=829297946878021632&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Rosa hotels ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/bba49e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f23a333a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dc088c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites [](https://www.expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) Costa del Este 9.4/10 Exceptional (252 reviews) "All units are very well equipped with everything that travelers will need. Comfortable and well located, easy access and safe neighborhood. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaime $148 nightly $163 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Food and drink](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/c1dda5ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves breakfast, lunch, and dinner](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/d12ac1da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/afc6d0da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/f53158fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Panama Metromall [](https://www.expedia.com/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) San Antonio 9.0/10 Wonderful (1,004 reviews) "Staff and facilities excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) August H. $110 nightly $121 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c579d87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/166e4001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/db85bc00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City [](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Juan Diaz 9.6/10 Exceptional (680 reviews) "As usual the stay was amazing in this hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose $249 nightly $274 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Free self parking](https://images.trvl-media.com/lodging/17000000/16120000/16111500/16111406/39ceae17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/17000000/16120000/16111500/16111406/6b4a6a0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16120000/16111500/16111406/ceb5b514.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/17000000/16120000/16111500/16111406/18177d00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Panama Canal Inn [](https://www.expedia.com/Panama-City-Hotels-Canal-Inn-BB-Panama.h16111406.Hotel-Information) Panama City 8.6/10 Excellent (19 reviews) "Excellent hotel, good location, nice stay and great service." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rocio Hernandez $54 nightly $60 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Canal-Inn-BB-Panama.h16111406.Hotel-Information) ![Daily buffet breakfast (PAB 21 per person)](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/22409c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/f95b4a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/c780324d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama [](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) San Francisco 8.6/10 Excellent (1,005 reviews) "Breakfast was great , clean room and staff was nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pauline $140 nightly $153 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/616200e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/4edef1fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w2560h3836x0y4-b9b31746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/6fa9ba2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Panama City [](https://www.expedia.com/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) Bella Vista 9.6/10 Exceptional (230 reviews) "Great staff and the food was amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nyrisha $142 nightly $156 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/f2fa3d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (In the heart of the City) | Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/c6c3b77c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (In the heart of the City) | Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/8d82f49a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Panama [](https://www.expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) Bella Vista 9.0/10 Wonderful (5,165 reviews) "It was an excellent area overall for staying. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kadiean $147 nightly $162 total Apr 27 - Apr 28 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/123000000/122990000/122982800/122982720/bfe823fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/123000000/122990000/122982800/122982720/52be3704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, microwave](https://images.trvl-media.com/lodging/123000000/122990000/122982800/122982720/3042f65a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, Garden View | Desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/123000000/122990000/122982800/122982720/ebafbcf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modal [](https://www.expedia.com/Panama-City-Hotels-Modal.h122982720.Hotel-Information) Panama City 9.0/10 Wonderful (2 reviews) "First of all, Expedia has it advertised as 10 minute walk or 3 minutes from airport. Far from the truth. 17km and 35 minutes 3 tolls away. No sign anywhere on the building and very dark at night. Our Uber driver could not find it neither. We finally got out and asked. Everything is modernized. Had to find the Email to find passcodes to enter. Found a women once we entered and wanted to know how we got in. 20 minutes later and in my junk mail. The building is new, everything clean. Everything!... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose $77 nightly $86 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Modal.h122982720.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/6ae0cc51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/34e202d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/8c9eeca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/5a0a24e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Felipe [](https://www.expedia.com/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) Casco Viejo 9.4/10 Exceptional (333 reviews) "I really enjoyed my stay here. The location was great and the staff is outstanding. " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Michael $139 nightly $153 total Apr 14 - Apr 15 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/23fa73c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/8d6ae106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed | Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/2fee40c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/234e399f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Panama [](https://www.expedia.com/Panama-City-Hotels-The-Westin-Panama.h5781845.Hotel-Information) Costa del Este 9.0/10 Wonderful (325 reviews) "Clean room, helpful staff, good breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie $206 nightly $226 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-The-Westin-Panama.h5781845.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/114000000/113560000/113553400/113553339/ca901e22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/114000000/113560000/113553400/113553339/06229a16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rainfall showerhead, hair dryer, slippers, towels](https://images.trvl-media.com/lodging/114000000/113560000/113553400/113553339/1a2bb11b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/114000000/113560000/113553400/113553339/68484199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Résidence Panamá [](https://www.expedia.com/Panama-City-Hotels-La-Residence-Panama.h113553339.Hotel-Information) Bella Vista 9.4/10 Exceptional (8 reviews) "Mauricio and Edinson were the stars of the place... they were always extremely helpful... always cheerful and welling to get out of their way to make sure clients are content. 100% recommended. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) khaled $163 nightly $179 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-La-Residence-Panama.h113553339.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/4235e7f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/d4b0e49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/9e56ccf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/a2139207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Panama City Hotel [](https://www.expedia.com/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information) Bella Vista 8.8/10 Excellent (172 reviews) "Very good hotel, well located. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrés $127 nightly $140 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/fe3d7092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/7b45a441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/dea447f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/93c6a3dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Panama Canal [](https://www.expedia.com/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) Amador 8.6/10 Excellent (1,005 reviews) "Lovely area to see the canal" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Graciela $86 nightly $95 total Apr 17 - Apr 18 Total with taxes and fees [](https://www.expedia.com/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/91ac7bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/3db8be94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/4ac2734a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/5b3a3c75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Plaza Paitilla Inn Hotel [](https://www.expedia.com/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) San Francisco 9.4/10 Exceptional (2,129 reviews) "Clean room, the staff were friendly as always. Amazing pool area and good food!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Claudia $103 nightly $114 total Apr 25 - Apr 26 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/08d313d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed, Partial Ocean View | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/2c21fbc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama [](https://www.expedia.com/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) San Francisco 9.0/10 Wonderful (1,000 reviews) "Very enjoyable stay" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Lynnette $269 nightly $296 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Superior Suite Duplex, Balcony, Sea View | In-room safe, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/83c9df4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite Duplex, Balcony, Sea View | Living area](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/9b59eaff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/1dd7c6ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/14d9a23b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bardot Boutique [](https://www.expedia.com/Panama-City-Hotels-Hotel-Bardot-Boutique.h119739302.Hotel-Information) Casco Viejo 9.4/10 Exceptional (13 reviews) "What a special place! Very reasonable rate for an amazing location. 2 level suite was sweet! Love the decor. The staff and restuarant/bar is magnificent in every way!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveler $127 nightly $141 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Hotel-Bardot-Boutique.h119739302.Hotel-Information) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/94455d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/49d1f8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/094aef75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Plaza by Wyndham Panama Punta Pacifica [](https://www.expedia.com/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) San Francisco 9.6/10 Exceptional (1,147 reviews) "Clean, spacious rooms, very nice and welcoming staff. Great breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erica $92 nightly $101 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/913328f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | City view](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/4c9a29b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/c772820f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waymore Hotel Spa & Casino [](https://www.expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) Bella Vista 8.8/10 Excellent (810 reviews) "The room and the breakfast are excelent, the staff is also really great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luiza $93 nightly $104 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/961958f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/69984cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/14a856db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá [](https://www.expedia.com/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) San Francisco 8.4/10 Very Good (1,471 reviews) "Nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David $169 nightly $186 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Outdoor pool, open 8:00 AM to 6:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/af0ce5c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/5b910cc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | View from room](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/243f1471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Executive Hotel [](https://www.expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) Bella Vista 9.2/10 Wonderful (1,037 reviews) "Great location, nice hotel with great friendly and courteous staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rogelio $92 nightly $101 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-11&endDate=2026-04-12®ionId=829297946878021632&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Rosa-Hotels.d829297946878021632.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Rosa-Hotels.d829297946878021632.Travel-Guide-Hotels) ## Top Santa Rosa Hotel Reviews ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 6/10 Okay "Yes" [](https://expedia.com/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Thank you for the nice stay. We’re looking forward to returning this weekend. This will be easy as our go-to place when traveling through Panama City for overnights. Thanks for a decent room at a reasonable price. Breakfast is not in the hotel but a 30 foot walk to next door. Just for those expecting that to be in the hotel, it’s only available next door and give yourself some time to get it as the service is a bit slower for hot meals." [](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Riande Urban Hotel](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/f3b8e5d4_y.jpg) ### Riande Urban Hotel 10/10 Excellent "Visited March 2026 from the U.S. Stayed for a week and had a great experience! The staff was friendly and helpful, and the property was well kept and clean. " [](https://expedia.com/Panama-City-Hotels-Riande-Urban-Hotel.h185277.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702_y.jpg) ### Waymore Hotel Spa & Casino 8/10 Good "My stay at waymore hotel was great. Breakfast was excellent and the staff kind and courteous I will stay here again and will refer others to you" [](https://expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Amazing breakfast selection a large variety very friendly and pleasant staff" [](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Ramada Plaza by Wyndham Panama Punta Pacifica](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b_y.jpg) ### Ramada Plaza by Wyndham Panama Punta Pacifica 10/10 Excellent "The staff was excellent and the overall facility was very clean and inviting " [](https://expedia.com/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "the hotel was close to both the airport and the places of interest" [](https://expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Aloft Panama](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/75c7ddd0_y.jpg) ### Aloft Panama 8/10 Good "The room, facility were clean. Breakfast was delicious" [](https://expedia.com/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg) ### The Executive Hotel 8/10 Good "I didn't stay that long, only a few hours, so I didn't have time to go explore the surroundings. " [](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ## More cheap stays in Santa Rosa ![HOTEL SAN THOMAS INN](https://images.trvl-media.com/lodging/102000000/101070000/101069500/101069427/6ca70005_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL SAN THOMAS INN AVE. JUSTO AROSEMENA, CALLE 33 Panama City $23 nightly $25 total Mar 29 - Mar 30 Total with taxes and fees 6.6/10 (60 reviews) [](https://expedia.com/Panama-City-Hotels-HOTEL-SAN-THOMAS-INN.h101069427.Hotel-Information) ![Hotel República](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/77400971_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel República Plaza 5 De Mayo Final Ave Panama City Panama $23 nightly $26 total Apr 10 - Apr 11 Total with taxes and fees 6.6/10 (188 reviews) [](https://expedia.com/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ![Panama House Bed & Breakfast](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/bf18b63d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Panama House Bed & Breakfast Calle 1era El Carmen- Casa # 32 Panama City $41 nightly $45 total Mar 29 - Mar 30 Total with taxes and fees 9/10 Wonderful! (197 reviews) [](https://expedia.com/Panama-City-Hotels-Panama-House-Bed-Breakfast.h11845091.Hotel-Information) ![Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals](https://images.trvl-media.com/lodging/60000000/59270000/59264500/59264464/b5e8c48b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals Avenida Peru Y Calle 30 Panama City Panama Province $62 nightly $68 total Apr 15 - Apr 16 Total with taxes and fees 7.4/10 Good! (237 reviews) [](https://expedia.com/Panama-City-Hotels-Veracruz-Hotel.h59264464.Hotel-Information) ![Magnolia Inn](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/60cd745e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Magnolia Inn 8-18 Calle 8 y Calle Boquete Panama City Panama $111 nightly $122 total Mar 31 - Apr 1 Total with taxes and fees 8.8/10 Excellent! (460 reviews) [](https://expedia.com/Panama-City-Hotels-Magnolia-Inn.h24165406.Hotel-Information) ![Arcadia Condo Suites](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Arcadia Condo Suites Calle rio mar Panama City Panamá Province $148 nightly $163 total Mar 31 - Apr 1 Total with taxes and fees 9.4/10 Exceptional! (252 reviews) [](https://expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ## Hotels in Santa Rosa with star-rating ![5 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/25600/25559/c6e0103a_z.jpg) 5 Star Hotels 11 properties [](https://expedia.com/5Star-Santa-Rosa-Hotels.s50-0-d829297946878021632.Travel-Guide-Filter-Hotels) ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 75 properties [](https://expedia.com/4Star-Santa-Rosa-Hotels.s40-0-d829297946878021632.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 234 properties [](https://expedia.com/3Star-Santa-Rosa-Hotels.s30-0-d829297946878021632.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 434 properties [](https://expedia.com/2Star-Santa-Rosa-Hotels.s20-0-d829297946878021632.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Santa Rosa? > This area is the heart of Santa Rosa, offering a convenient base for exploring the city. You'll find a concentration of local businesses, dining options, and access to public transportation. The Parque Central is a key landmark, providing a central gathering spot. > > > For travelers who appreciate convenience and easy access to local amenities, staying in the city center is ideal. ### When is the best time to go to Santa Rosa? > During these months, you'll experience sunny days with lower humidity and minimal rainfall, making it ideal for outdoor activities like hiking, wildlife viewing, and enjoying the beaches. The clearer skies also provide better conditions for photography and sightseeing. > > > Travelers looking for a relaxed and pleasant experience will find this time particularly suitable. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Rosa hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Santa Rosa hotel? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app