Title: Santana Vacation Rentals from $154: Search Short-Term Rentals | Expedia.com

[Hotels in Santana](https://expedia.com/Santana-Hotels.d728928322594840576.Travel-Guide-Hotels)[Car Rentals in Santana](https://expedia.com/Car-Rentals-In-Santana.d728928322594840576.Car-Rental-Guide)[Santana Vacation Packages](https://expedia.com/Santana.d728928322594840576.Destination-Travel-Guides)

![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium)

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg)  
###  
Bundle & Save  
Get more, spend less whenever you see Bundle & Save deals
- ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg)  
###  
OneKeyCash  
Earn OneKeyCash on all your eligible bookings
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg)  
###  
Upfront pricing  
We are not like the others - we include taxes and fees

## Check prices for these dates

In two weeks

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=728928322594840576&startDate=2026-03-06&endDate=2026-03-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=728928322594840576&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 15 - May 17](https://www.expedia.com/Hotel-Search?regionId=728928322594840576&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 12 - Jun 14](https://www.expedia.com/Hotel-Search?regionId=728928322594840576&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santana vacation rentals

![Beach](https://images.trvl-media.com/lodging/107000000/106620000/106619100/106619082/11ed5d26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/107000000/106620000/106619100/106619082/5c735cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/107000000/106620000/106619100/106619082/d4061f8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/107000000/106620000/106619100/106619082/e9ff13cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy 2-bedroom apartment in charming Arecibo with WiFi, AC

[](https://www.expedia.com/Arecibo-Hotels-Cozy-2-Bedroom-Apartment-In-Charming-Arecibo-With-WiFi.h106619082.Hotel-Information)

Arecibo

10/10

Exceptional

(2 reviews)

"Nice place to stay, sleep and go out!! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rosa

$175 nightly

$186 total

Feb 22 - Feb 23

Total with taxes and fees

[](https://www.expedia.com/Arecibo-Hotels-Cozy-2-Bedroom-Apartment-In-Charming-Arecibo-With-WiFi.h106619082.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/101000000/100010000/100009700/100009679/c8092710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/101000000/100010000/100009700/100009679/w4096h2424x0y4-c34c757a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/101000000/100010000/100009700/100009679/73d9780e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/101000000/100010000/100009700/100009679/609aa2e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

[](https://www.expedia.com/Adjuntas-Hotels-The-Cozy-Casata-A-Unique-American-Style-Cabin-In-The-Mountains-Of-Puerto-Rico.h100009679.Hotel-Information)

Adjuntas

9.6/10

Exceptional

(13 reviews)

"A beautiful home and a great host! Strongly recommend! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brandon C.

$264 nightly

$280 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Adjuntas-Hotels-The-Cozy-Casata-A-Unique-American-Style-Cabin-In-The-Mountains-Of-Puerto-Rico.h100009679.Hotel-Information)

![VA 201 Deluxe Views of the Atlantic, Family Suite / Kitchen / 1 Full Size  Bed and 2 Twin/Twin Bunk | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/11000000/10280000/10272300/10272292/eb6bffc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![VA 201 Deluxe Views of the Atlantic, Family Suite / Kitchen / 1 Full Size  Bed and 2 Twin/Twin Bunk | Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/11000000/10280000/10272300/10272292/a443706d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![VA 102a Junior Ocean View Suite, 1 Full/Twin Size Bunk Bed, Ocean Front  Property | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/11000000/10280000/10272300/10272292/59919a91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![VA 201 Deluxe Views of the Atlantic, Family Suite / Kitchen / 1 Full Size  Bed and 2 Twin/Twin Bunk | Beach/ocean view](https://images.trvl-media.com/lodging/11000000/10280000/10272300/10272292/41351563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ventana al Atlantico at Arecibo 681 Ocean Drive

[](https://www.expedia.com/Arecibo-Hotels-Ventana-Al-Atlantico-Boutique-Hotel-At-Arecibo-681-Ocean-Drive.h10272292.Hotel-Information)

Arecibo

7.0/10

Good

(259 reviews)

"The room was clean and the host was a great help. The view was beautiful. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gustavo

$144 nightly

$154 total

Feb 20 - Feb 21

Total with taxes and fees

[](https://www.expedia.com/Arecibo-Hotels-Ventana-Al-Atlantico-Boutique-Hotel-At-Arecibo-681-Ocean-Drive.h10272292.Hotel-Information)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/120000000/119700000/119697600/119697597/7299c95b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119700000/119697600/119697597/569d5913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/120000000/119700000/119697600/119697597/5e5529e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/120000000/119700000/119697600/119697597/ab337367.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy 2BR house w/ AC & WiFi in Utuado near Tanama River

[](https://www.expedia.com/Utuado-Hotels-Cozy-2BR-House-W-AC-WiFi-In-Utuado-Near-Tanama-River.h119697597.Hotel-Information)

Utuado

10/10

Exceptional

(1 review)

$198 nightly

$210 total

Feb 22 - Feb 23

Total with taxes and fees

[](https://www.expedia.com/Utuado-Hotels-Cozy-2BR-House-W-AC-WiFi-In-Utuado-Near-Tanama-River.h119697597.Hotel-Information)

![Beach nearby, sun loungers, beach towels](https://images.trvl-media.com/lodging/100000000/99450000/99440700/99440607/cf475bc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/100000000/99450000/99440700/99440607/65c7243a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/100000000/99450000/99440700/99440607/w449h683x288y0-88314102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/100000000/99450000/99440700/99440607/ac473a88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa Colon near beach and Top Attractions, Wi-Fi

[](https://www.expedia.com/Arecibo-Hotels-Stylish-Coast-Beach-Villa-Top-Attractions.h99440607.Hotel-Information)

Arecibo

10/10

Exceptional

(1 review)

"My family and I stayed here while visiting family in the area. It is a great location, close to the beach, pharmacy, bakery, and convenience store all within walking distance."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hyomara H.

$186 nightly

$198 total

Feb 23 - Feb 24

Total with taxes and fees

[](https://www.expedia.com/Arecibo-Hotels-Stylish-Coast-Beach-Villa-Top-Attractions.h99440607.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/124000000/123910000/123908800/123908783/032472d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/124000000/123910000/123908800/123908783/c4dfa445.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/124000000/123910000/123908800/123908783/cd91c5ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/124000000/123910000/123908800/123908783/df735f02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Boho Apt near Ojo de agua and near beach in Vega Baja, Puerto Rico

[](https://www.expedia.com/Vega-Baja-Hotels-Enjoy-A-Cozy-And-Modern.h123908783.Hotel-Information)

Vega Baja

10/10

Exceptional

(2 reviews)

"We had such a great stay! Roberto was absolutely wonderful, incredible communication from check in to check out! We would definitely stay again when we return to Puerto Rico! Thank you so much Roberto!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tiffany

$172 nightly

$182 total

Mar 4 - Mar 5

Total with taxes and fees

[](https://www.expedia.com/Vega-Baja-Hotels-Enjoy-A-Cozy-And-Modern.h123908783.Hotel-Information)

![Beach nearby](https://images.trvl-media.com/lodging/96000000/95820000/95811900/95811814/010b0e49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/96000000/95820000/95811900/95811814/a1fd6026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95820000/95811900/95811814/d875877e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95820000/95811900/95811814/aae63438.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private Studio at El Flamingo Beach Club

[](https://www.expedia.com/Manati-Hotels-Charming-Studio-Retreat-At-El-Flamingo-Beach-Club-6.h95811814.Hotel-Information)

Tierras Nuevas Poniente

8.8/10

Excellent

(3 reviews)

"It was a nice place to stay with a few options for dinning near by. And only a ten minute drive into the city over to find more night life. Also it’s in close vicinity to the most popular beaches in Manatí. Definitely would stay here again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Denaysia G.

$196 nightly

$211 total

Feb 21 - Feb 22

Total with taxes and fees

[](https://www.expedia.com/Manati-Hotels-Charming-Studio-Retreat-At-El-Flamingo-Beach-Club-6.h95811814.Hotel-Information)

![Beach towels](https://images.trvl-media.com/lodging/102000000/101260000/101255600/101255600/1d3fb2e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/102000000/101260000/101255600/101255600/w1440h1290x0y0-5dd17ea9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/102000000/101260000/101255600/101255600/d22904d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/102000000/101260000/101255600/101255600/d4538842.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baja Vacation Home with Solar, WiFi and AC

[](https://www.expedia.com/Vega-Baja-Hotels-Spacious-House-With-Lagoon-View-5-Minutes-From-Beach.h101255600.Hotel-Information)

Vega Baja

10/10

Exceptional

(1 review)

"The property was well kept and secured! I was traveling with my family for my son's farewell vacation prior to heading out for college... The kitchen set up was perfect for breakfast's prior to heading out for the day. There is a small grocery store on the road headed out toward the main road which was also very convenient for all of our needs! I would definitely look to forward to booking this space again if I'm on this side of the Island again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Roberto A.

$395 nightly

$420 total

Feb 22 - Feb 23

Total with taxes and fees

[](https://www.expedia.com/Vega-Baja-Hotels-Spacious-House-With-Lagoon-View-5-Minutes-From-Beach.h101255600.Hotel-Information)

![Sun loungers, beach towels](https://images.trvl-media.com/lodging/118000000/117110000/117101100/117101061/b53a5a34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/118000000/117110000/117101100/117101061/3811efe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/118000000/117110000/117101100/117101061/cecd02cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/118000000/117110000/117101100/117101061/9cba2716.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### CH 1003: Cozy studio with kitchenette, WiFi & Pool, CH 1003: Cozy studio in amazing Manatí with AC, ...

[](https://www.expedia.com/Manati-Hotels-CH-1003-Cozy-Studio-With-Kitchenette.h117101061.Hotel-Information)

Tierras Nuevas Saliente

9.0/10

Wonderful

(4 reviews)

"Host was graat and i would definitely go back. Amenities were as described and stay was pleasant. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

J G.

$123 nightly

$123 total

Mar 12 - Mar 13

Total with taxes and fees

[](https://www.expedia.com/Manati-Hotels-CH-1003-Cozy-Studio-With-Kitchenette.h117101061.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/120000000/119110000/119103700/119103657/69226590.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/120000000/119110000/119103700/119103657/4666a18b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119110000/119103700/119103657/9a7a2fae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/120000000/119110000/119103700/119103657/bb0cb741.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Eden Oasis - A Private Getaway

[](https://www.expedia.com/Arecibo-Hotels-The-Eden-Oasis-A-Private-Getaway.h119103657.Hotel-Information)

Bajadero

10/10

Exceptional

(1 review)

"The home was beautiful and it was close to the beaches and restaurants. We had a wonderful stay and there were several pleasant surprises. The host was very responsive and welcoming!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gladys G.

$205 nightly

$218 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Arecibo-Hotels-The-Eden-Oasis-A-Private-Getaway.h119103657.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/121000000/120470000/120461500/120461437/075b9981.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/121000000/120470000/120461500/120461437/6b77052c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/121000000/120470000/120461500/120461437/b3a10e0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/121000000/120470000/120461500/120461437/df4df331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### VSS La Puntilla Stylish Coastal Getaway Near Beach

[](https://www.expedia.com/Arecibo-Hotels-VSS-La-Puntilla-Stylish-Coastal-Getaway.h120461437.Hotel-Information)

Arecibo

$181 nightly

$181 total

Feb 23 - Feb 24

Total with taxes and fees

[](https://www.expedia.com/Arecibo-Hotels-VSS-La-Puntilla-Stylish-Coastal-Getaway.h120461437.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/119000000/118960000/118950700/118950635/7378a2c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, wheelchair access](https://images.trvl-media.com/lodging/119000000/118960000/118950700/118950635/5fd0e504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/119000000/118960000/118950700/118950635/w1206h1507x0y0-71717f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/119000000/118960000/118950700/118950635/7239ffc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DtMF Experience at his Hometown in Vega Baja - Near Beach and Natural Springs!

[](https://www.expedia.com/Vega-Baja-Hotels-Live-The-DtMF-ExperienceVega-Baja-Stay-Near-Beach.h118950635.Hotel-Information)

Vega Baja

10/10

Exceptional

(2 reviews)

"This place is very confortable"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carmen Iris F.

$161 nightly

$171 total

Mar 4 - Mar 5

Total with taxes and fees

[](https://www.expedia.com/Vega-Baja-Hotels-Live-The-DtMF-ExperienceVega-Baja-Stay-Near-Beach.h118950635.Hotel-Information)

![Basic Double Room Single Use | Private kitchen | Coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/76000000/75280000/75275700/75275639/38f6ad90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/76000000/75280000/75275700/75275639/787520db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Double Room Single Use | Terrace/patio](https://images.trvl-media.com/lodging/76000000/75280000/75275700/75275639/w810h955x0y0-b2c05d1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Double Room Single Use | Individually decorated, individually furnished, iron/ironing board](https://images.trvl-media.com/lodging/76000000/75280000/75275700/75275639/9a5580de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Arecibo Hotel 2105

[](https://www.expedia.com/Arecibo-Hotels-Arecibo-Hotel-2105.h75275639.Hotel-Information)

Arecibo

7.8/10

Good

(10 reviews)

"The apartment was excellent for a family of 4 . It was very clean with all the appliances you would need to call it home. The process was simple and communication with a representative was excellent. Highly recommend."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alfredo

$160 nightly

$174 total

Feb 24 - Feb 25

Total with taxes and fees

[](https://www.expedia.com/Arecibo-Hotels-Arecibo-Hotel-2105.h75275639.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/83000000/82880000/82875300/82875283/1cca885c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/83000000/82880000/82875300/82875283/26d85f8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/83000000/82880000/82875300/82875283/280550bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/83000000/82880000/82875300/82875283/6c0ef5b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa Mar2

[](https://www.expedia.com/Vega-Baja-Hotels-Vrbo-Property.h82875283.Hotel-Information)

Vega Baja

9.6/10

Exceptional

(4 reviews)

"Brenda & Juan have created a beautiful place you can call home not too far from San Juan. I felt like I was in my own personal resort. The pool was so refreshing and if you would like you can eat dinner in at their small guests only restaurant. Cerró Gordo beach is about 20 minutes away and is another treasure. So grateful to have found this spot."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shannon F.

$269 nightly

$285 total

Feb 23 - Feb 24

Total with taxes and fees

[](https://www.expedia.com/Vega-Baja-Hotels-Vrbo-Property.h82875283.Hotel-Information)

![Fridge, coffee/tea maker, cookware/dishes/utensils, lobster pot](https://images.trvl-media.com/lodging/98000000/97080000/97073700/97073650/132c7e87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![5 bedrooms, bed sheets](https://images.trvl-media.com/lodging/98000000/97080000/97073700/97073650/cf1b3af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![5 bedrooms, bed sheets](https://images.trvl-media.com/lodging/98000000/97080000/97073700/97073650/5d84587a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![5 bedrooms, bed sheets](https://images.trvl-media.com/lodging/98000000/97080000/97073700/97073650/da4dac73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hacienda Vista Del Rio 1

[](https://www.expedia.com/Orocovis-Hotels-Vrbo-Property.h97073650.Hotel-Information)

Orocovis

$183 nightly

$194 total

Feb 21 - Feb 22

Total with taxes and fees

[](https://www.expedia.com/Orocovis-Hotels-Vrbo-Property.h97073650.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/118000000/117380000/117378800/117378757/8827b04f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/118000000/117380000/117378800/117378757/601f764c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi](https://images.trvl-media.com/lodging/118000000/117380000/117378800/117378757/78fcef49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi](https://images.trvl-media.com/lodging/118000000/117380000/117378800/117378757/8e61131c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DK Backyard - Yellow Room

[](https://www.expedia.com/Arecibo-Hotels-DK-Backyard-Yellow-Room.h117378757.Hotel-Information)

Arecibo

10/10

Exceptional

(1 review)

"Exelente estancia🙏"

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

Liliana

$157 nightly

$157 total

Feb 22 - Feb 23

Total with taxes and fees

[](https://www.expedia.com/Arecibo-Hotels-DK-Backyard-Yellow-Room.h117378757.Hotel-Information)

![Microwave](https://images.trvl-media.com/lodging/121000000/120450000/120441700/120441609/0ba7d37d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/121000000/120450000/120441700/120441609/dbc5e09e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120450000/120441700/120441609/fd15decd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/121000000/120450000/120441700/120441609/450e1f8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marie Guest House w A/C

[](https://www.expedia.com/Camuy-Hotels-Marie-Guest-House-W-AC.h120441609.Hotel-Information)

Camuy

$240 nightly

$255 total

Feb 22 - Feb 23

Total with taxes and fees

[](https://www.expedia.com/Camuy-Hotels-Marie-Guest-House-W-AC.h120441609.Hotel-Information)

![Basic Room | Living area | 55-inch LED TV with digital channels](https://images.trvl-media.com/lodging/79000000/78290000/78284000/78283907/4f35b504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Room | Living area | 55-inch LED TV with digital channels](https://images.trvl-media.com/lodging/79000000/78290000/78284000/78283907/54ad9465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/79000000/78290000/78284000/78283907/13fa182e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Room | Individually decorated, individually furnished, iron/ironing board](https://images.trvl-media.com/lodging/79000000/78290000/78284000/78283907/ba2535ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Arecibo Hotel 2104

[](https://www.expedia.com/Arecibo-Hotels-Arecibo-Hotel-2104.h78283907.Hotel-Information)

Arecibo

7.0/10

Good

(12 reviews)

"Convenient, clean, excellent communication throughout. Very happy with our stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Henry

$155 nightly

$169 total

Mar 3 - Mar 4

Total with taxes and fees

[](https://www.expedia.com/Arecibo-Hotels-Arecibo-Hotel-2104.h78283907.Hotel-Information)

![Private kitchen](https://images.trvl-media.com/lodging/113000000/112370000/112362200/112362143/1d1a51cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/113000000/112370000/112362200/112362143/07ccf16d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/113000000/112370000/112362200/112362143/e4b61f97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/113000000/112370000/112362200/112362143/24ffe03c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2-bedroom house in awesome Quebradillas with AC, WiFi

[](https://www.expedia.com/Quebradillas-Hotels-Charming-2-Bedroom-House-In-Awesome-Quebradillas-With-AC.h112362143.Hotel-Information)

Quebradillas

10/10

Exceptional

(1 review)

"yes and yes I some problem finding it, but the was good place and clean"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

LUCAS A.

$177 nightly

$188 total

Feb 23 - Feb 24

Total with taxes and fees

[](https://www.expedia.com/Quebradillas-Hotels-Charming-2-Bedroom-House-In-Awesome-Quebradillas-With-AC.h112362143.Hotel-Information)

![CLin 101 Casita Linda - 1 King / 1 Futon 1st Floor | Individually decorated, individually furnished](https://images.trvl-media.com/lodging/103000000/102690000/102684100/102684028/24dc5eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room dining](https://images.trvl-media.com/lodging/103000000/102690000/102684100/102684028/fbcc14a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![CLin 101 Casita Linda - 1 King / 1 Futon 1st Floor | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/103000000/102690000/102684100/102684028/b91bab2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![CLin 101 Casita Linda - 1 King / 1 Futon 1st Floor | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/103000000/102690000/102684100/102684028/b0f07a2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casita Linda

[](https://www.expedia.com/Arecibo-Hotels-Casita-Linda.h102684028.Hotel-Information)

Arecibo

8.4/10

Very Good

(7 reviews)

"Angel worked us in on a same-day booking and met with us at 9:00pm for check and was truly a holiday life-saver (thanks to a different VRBO booking never responding on check in). Nice amenities and right next to ocean (more surfing spot rather than swimming, but pool was nice as well). With more times notice and some updates, this place could easily be 5 star. Again, super thanks to Angel for the last-minute accomodations."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Justin

$194 nightly

$218 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Arecibo-Hotels-Casita-Linda.h102684028.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-05&endDate=2026-03-06&regionId=728928322594840576&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=VR_SPRING_PROMO_728928322594840576)

## Find vacation rentals that suit your style

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Arecibo%2C+Puerto+Rico&regionId=728928322594840576&latLong=18.453855%2C-66.663296&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Arecibo%2C+Puerto+Rico&regionId=728928322594840576&latLong=18.453855%2C-66.663296&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=APARTMENT)

Villas

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Arecibo%2C+Puerto+Rico&regionId=728928322594840576&latLong=18.453855%2C-66.663296&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=VILLA)

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Arecibo%2C+Puerto+Rico&regionId=728928322594840576&latLong=18.453855%2C-66.663296&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=CABIN)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Arecibo%2C+Puerto+Rico&regionId=728928322594840576&latLong=18.453855%2C-66.663296&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=APART_HOTEL)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Arecibo%2C+Puerto+Rico&regionId=728928322594840576&latLong=18.453855%2C-66.663296&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=CONDO)

Chalets

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Arecibo%2C+Puerto+Rico&regionId=728928322594840576&latLong=18.453855%2C-66.663296&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=CHALET)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Arecibo%2C+Puerto+Rico&regionId=728928322594840576&latLong=18.453855%2C-66.663296&adults=2&startDate=2026-05-20&d1=2026-05-20&endDate=2026-05-23&d2=2026-05-23&lodging=COTTAGE)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in

](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantana-Vacation-Rentals.d728928322594840576.Travel-Guide-VacationRentals)[

Sign up, it's free

](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantana-Vacation-Rentals.d728928322594840576.Travel-Guide-VacationRentals)

## Top Santana Hotel Reviews

![Hotel El Guajataca](https://images.trvl-media.com/lodging/3000000/2050000/2040200/2040127/2180ee43_y.jpg)

### Hotel El Guajataca

10/10 Excellent

"Love it! The View is very beautiful!!"

[](https://expedia.com/Quebradillas-Hotels-Hotel-El-Guajataca.h2040127.Hotel-Information)

![Hyatt Place Manati](https://images.trvl-media.com/lodging/8000000/7010000/7008800/7008739/1a6c7b49_y.jpg)

### Hyatt Place Manati

10/10 Excellent

"Rooms were clean and spacious, comfy beds, no smell, bathtubs in bathroom. Breakfast was convenient as well although wished it didn’t finish as early as 9\. "

[](https://expedia.com/Manati-Hotels-Hyatt-Place-Manati.h7008739.Hotel-Information)

![Casa Grande Mountain Retreat - Adults Only](https://images.trvl-media.com/lodging/68000000/67660000/67659600/67659544/0055be02_y.jpg)

### Casa Grande Mountain Retreat - Adults Only

10/10 Excellent

"The staff was tan amable and welcoming! I had to reach out to the property to adjust dates and they were so accommodating! The propriety was well kept and more beautiful than the fotos. The cafe selection was delicious and reasonably priced. Try the cafe con leche, made from a local coffee farm. Side note: the yoga is $20 a session although the website says it’s included in the price. Just for transparency. It gets cold up there and the blanket is muslin material, pack some sweats you won’t regret it. Closest store is 27 minutes away on windy roads. Keep that in mind before checking in and save a trip. Stop by on the side road restaurants for drinks and treats Willie’s sports bar was refreshing and the view is gorgeous (cash only bar). "

[](https://expedia.com/Utuado-Hotels-Casa-Grande-Mountain-Retreat.h67659544.Hotel-Information)

![Vacation Rental Arecibo PR](https://images.trvl-media.com/lodging/113000000/112540000/112536200/112536114/b456be72_y.jpg)

### Vacation Rental Arecibo PR

10/10 Excellent

"Great stay, clean and awesome location. Highly recommend!!"

[](https://expedia.com/Arecibo-Hotels-Vacation-Rental-Arecibo-PR.h112536114.Hotel-Information)

![Parador El Buen Café](https://images.trvl-media.com/lodging/1000000/980000/978700/978601/27ba25cf_y.jpg)

### Parador El Buen Café

10/10 Excellent

"Everything was wonderful "

[](https://expedia.com/Hatillo-Hotels-Parador-El-Buen-Cafe.h978601.Hotel-Information)

![Arecibo Inn](https://images.trvl-media.com/lodging/10000000/9700000/9690800/9690745/8d81cb1e_y.jpg)

### Arecibo Inn

10/10 Excellent

"The room was clean, good smell, comfortable, good accessibility for handicap. Secure."

[](https://expedia.com/Arecibo-Hotels-Arecibo-Inn.h9690745.Hotel-Information)

![Casita Manati](https://images.trvl-media.com/lodging/122000000/121440000/121436400/121436380/ea3b54ac_y.jpg)

### Casita Manati

10/10 Excellent

"Super clean plenty of space easy instructions for check in and great customer service "

[](https://expedia.com/Manati-Hotels-Casita-Manati.h121436380.Hotel-Information)

![Melao Lodge - Boutique Hotel](https://images.trvl-media.com/lodging/84000000/83470000/83462200/83462146/f6a9eb28_y.jpg)

### Melao Lodge - Boutique Hotel

10/10 Excellent

"Yes to dogs! Mananger made sure i knew how to work all the doors."

[](https://expedia.com/Vega-Baja-Hotels-Melao-Lodge.h83462146.Hotel-Information)

![Gorgeous beach house in Vega Baja @ Mare Blu](https://images.trvl-media.com/lodging/103000000/102400000/102393500/102393497/b52f69f3_y.jpg)

### Gorgeous beach house in Vega Baja @ Mare Blu

10/10 Excellent

"The apartment is very comfortable and has a full kitchen. It's close to the beach, just cross the street after a small road. The balcony on the 2nd floor has a view to the beach, but we preferred to walk to the waterfront benches and walkway. We had pur.morning cofee watching the ocean. We saw a whale tail and water sprout from the bench! (Winter is whale season.) The communication was good. The washer and dryer very convenient , specially because our grandson infant visited us. They provide all we needed for enjoying the beach: towels, seats. The kitchen had ceramic pots and all the kitchenware we needed. There's an outdoor table and shower. 2 parking spaces. We will most likely return."

[](https://expedia.com/Vega-Baja-Hotels-Stylish-Beach-House-In-Vega-Baja-Steps-From-The-Beach.h102393497.Hotel-Information)

## Find out more about Santana

**Everything you need to know about Santana vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santana vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santana vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santana vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santana. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santana in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $154 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santana rentals**

At Expedia, we put the best Santana vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santana rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santana vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santana. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com

### Trending destinations on Expedia.com

- [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals)
- [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals)
- [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals)
- [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals)
- [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals)
- [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals)
- [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals)
- [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals)
- [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals)
- [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals)
- [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals)
- [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals)
- [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals)
- [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)
- [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals)
- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

## Frequently asked questions

### Can I find a vacation rental in Santana?

### What are some of the best vacation home rentals in Santana?

### What can I see and do in Santana?

### What are vacation rentals like in Santana?

![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg)

## Go further with the Expedia app

Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app