Title: Visit South Eastern Region: 2026 Travel Guide for South Eastern Region, Malta | Expedia.com [South Eastern Region Hotels](https://expedia.com/Destinations-In-South-Eastern-Region.d708606516594679808.Hotel-Destinations)[Vacation Rentals in South Eastern Region](https://expedia.com/Destinations-In-South-Eastern-Region.d708606516594679808.Vacation-Rental-Destinations)[South Eastern Region Flights](https://expedia.com/Destinations-In-South-Eastern-Region.d708606516594679808.Flight-Destinations)[Things to do in South Eastern Region](https://expedia.com/Things-To-Do-In-South-Eastern-Region.d708606516594679808.Travel-Guide-Activities)[Car Rentals in South Eastern Region](https://expedia.com/Destinations-In-South-Eastern-Region.d708606516594679808.Car-Rental-Destinations)[South Eastern Region Vacations](https://expedia.com/South-Eastern-Region.d708606516594679808.Destination-Travel-Guides) # South Eastern Region ## Malta ![A public garden in Valletta with a view over the Grand Harbour, the location of the 1565 Great Siege when the Ottoman Empire tried, unsuccessfully, to invade Malta, then held by the Knights of St John. #Hometown #lifeatexpedia #history](https://images.trvl-media.com/place/2341/f0d37574-d737-4b42-a97e-de9b4bca1245.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![A public garden in Valletta with a view over the Grand Harbour, the location of the 1565 Great Siege when the Ottoman Empire tried, unsuccessfully, to invade Malta, then held by the Knights of St John. #Hometown #lifeatexpedia #history](https://images.trvl-media.com/place/2341/f0d37574-d737-4b42-a97e-de9b4bca1245.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Valletta in Malta : View from the Upper Barraka Gardens on the harbour. ](https://images.trvl-media.com/place/2341/13b95e7d-2bfe-41b1-ba95-675eec0f6396.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![The way I see things, Marsaxlokk is not a place to charm you at first sight. But then, silently, as time goes by, it creeps into your heart and makes you start wondering-- 'Do I really have to leave?'... :) #colorful #waterlust](https://images.trvl-media.com/place/6234061/4996c31f-3f9b-40aa-80de-a09c20a2b1f8.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Valletta is the European Capital of Culture this year, and it means that the city is full of cultural events all year. If you're planning to visit, this it the year to do it!](https://images.trvl-media.com/place/2341/c68cd87c-fa39-4646-9116-7a45f14e2858.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ### Popular cities in South Eastern Region [Valletta Known for Ports, Historical and Cathedrals ](https://expedia.com/Valletta.dx2341) Tour the capital of the Mediterranean island of Malta. This medieval fortified citadel has spectacular churches, palaces and religious art. ## Reasons to visit - Malta Experience - St. Johns Co - Cathedral - Upper Barrakka Gardens [Explore City](https://expedia.com/Valletta.dx2341)[Find Hotels](https://expedia.com/Valletta-Hotels.d2341.Travel-Guide-Hotels) [Floriana Known for Friendly people, Dining and Ports ](https://expedia.com/Floriana.dx6233901) Experience romantic Floriana: its food, oceanfront, beaches, and more! ## Reasons to visit - The Valletta Waterfront [Explore City](https://expedia.com/Floriana.dx6233901)[Find Hotels](https://expedia.com/Floriana-Hotels.d6233901.Travel-Guide-Hotels) [Birgu Known for Romantic, Family-friendly and Shopping ](https://expedia.com/Birgu.dx6234091) Come to romantic Birgu and enjoy its marina, food, and history. [Explore City](https://expedia.com/Birgu.dx6234091)[Find Hotels](https://expedia.com/Birgu-Hotels.d6234091.Travel-Guide-Hotels) [Marsaskala Known for Friendly people, Relaxing and Cafes ](https://expedia.com/Marsaskala.dx601857) Experience relaxing Marsaskala: its island views, cafes, and more! [Explore City](https://expedia.com/Marsaskala.dx601857)[Find Hotels](https://expedia.com/Marsaskala-Hotels.d601857.Travel-Guide-Hotels) [Marsaxlokk Known for Friendly people, Ports and Dining ](https://expedia.com/Marsaxlokk.dx6234061) Quaint Marsaxlokk awaits: its fishing, food, and more! [Explore City](https://expedia.com/Marsaxlokk.dx6234061)[Find Hotels](https://expedia.com/Marsaxlokk-Hotels.d6234061.Travel-Guide-Hotels) [Cospicua Known for Historical, Romantic and Swimming ](https://expedia.com/Cospicua.dx6234081) Escape to romantic Cospicua! Enjoy its churches, history, and castle. [Explore City](https://expedia.com/Cospicua.dx6234081)[Find Hotels](https://expedia.com/Cospicua-Hotels.d6234081.Travel-Guide-Hotels) ## Cities in South Eastern Region ![Valletta which includes a city, a sunset and heritage architecture](https://images.trvl-media.com/place/2341/596c4b66-7078-4204-b5cd-aedeb535880b.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Valletta Tour the capital of the Mediterranean island of Malta. This medieval fortified citadel has spectacular churches, palaces and religious art. ![Kalkara which includes a bay or harbor and a coastal town](https://images.trvl-media.com/place/6161207/87f1ed27-3bdc-4f9c-a343-aefe3f3e6dd6.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Kalkara Perched on the edge of the Grand Harbour is Kalkara, a village known for historic forts and delightful boats. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_708606516594679808) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app