$242 Cheap American Airlines flights Tri-Cities (TRI) to Charlotte (CLT)

Scoring cheap one-way American Airlines flights from TRI to CLT from $242 on Expedia couldn't be simpler --- just filter by "Price (lowest to highest)." Or check out our budget-friendly round-trip fares from $309 for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Begin your search one to three months ahead of your travel date to get cheaper fares on American Airlines flights from Tri-Cities Regional Airport (TRI) to Charlotte-Douglas Intl. Airport (CLT). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Nail your timing, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The earliest flight from TRI to CLT with American Airlines departs at 5:06AM UTC-5. You'll touch down at 6:33AM UTC-5. The final American Airlines flight of the day takes off at 8:27PM UTC-5 and arrives at 9:49PM UTC-5. With 20% fewer cancellations for departures before midday, starting your travel day early is often the smartest choice.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.