$559 Cheap Flights from Cairo (CAI) to Panama City (PTY)

View $559 flight on Wed, Feb 18, 2026Opens in a new window

Popular airlines from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Cairo to Panama City (CAI-PTY)

Prices were available within the past 7 days and start at $559 for one-way flights and $871 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Tue, Mar 24 - Tue, Mar 31
CAI
Cairo
PTY
Panama City
$871 Roundtrip, found 3 days ago
$871
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Tue, Mar 24 from Cairo to Panama City, returning Tue, Mar 31, priced at $871 found 3 days ago
Lufthansa
Tue, Mar 24 - Tue, Mar 31
CAI
Cairo
PTY
Panama City
$872 Roundtrip, found 3 days ago
$872
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Tue, Mar 24 from Cairo to Panama City, returning Tue, Mar 31, priced at $872 found 3 days ago
Lufthansa
Tue, Mar 24 - Tue, Mar 31
CAI
Cairo
PTY
Panama City
$904 Roundtrip, found 3 days ago
$904
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Tue, Mar 24 from Cairo to Panama City, returning Tue, Mar 31, priced at $904 found 3 days ago
Lufthansa
Tue, Mar 24 - Tue, Mar 31
CAI
Cairo
PTY
Panama City
$917 Roundtrip, found 3 days ago
$917
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Tue, Mar 24 from Cairo to Panama City, returning Tue, Mar 31, priced at $917 found 3 days ago
Lufthansa
Tue, Mar 24 - Tue, Mar 31
CAI
Cairo
PTY
Panama City
$968 Roundtrip, found 3 days ago
$968
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Tue, Mar 24 from Cairo to Panama City, returning Tue, Mar 31, priced at $968 found 3 days ago
American Airlines
Tue, Nov 11 - Tue, Dec 2
CAI
Cairo
PTY
Panama City
$995 Roundtrip, found 1 day ago
$995
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Nov 11 from Cairo to Panama City, returning Tue, Dec 2, priced at $995 found 1 day ago
American Airlines
Tue, Mar 24 - Tue, Mar 31
CAI
Cairo
PTY
Panama City
$1,010 Roundtrip, found 3 days ago
$1,010
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Mar 24 from Cairo to Panama City, returning Tue, Mar 31, priced at $1,010 found 3 days ago
United
Tue, Nov 11 - Tue, Dec 2
CAI
Cairo
PTY
Panama City
$1,065 Roundtrip, found 1 day ago
$1,065
Roundtrip
found 1 day ago
Select United flight, departing Tue, Nov 11 from Cairo to Panama City, returning Tue, Dec 2, priced at $1,065 found 1 day ago
Air France
Fri, Dec 5 - Wed, Dec 10
CAI
Cairo
PTY
Panama City
$1,179 Roundtrip, found 2 days ago
$1,179
Roundtrip
found 2 days ago
Select Air France flight, departing Fri, Dec 5 from Cairo to Panama City, returning Wed, Dec 10, priced at $1,179 found 2 days ago
KLM
Tue, Nov 11 - Tue, Dec 2
CAI
Cairo
PTY
Panama City
$1,378 Roundtrip, found 1 day ago
$1,378
Roundtrip
found 1 day ago
Select KLM flight, departing Tue, Nov 11 from Cairo to Panama City, returning Tue, Dec 2, priced at $1,378 found 1 day ago

Frequently asked questions

How much does a flight from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY) cost?
Secure a cheap one-way flight from $559 or cheap return flight from $871 from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)?
March is the least expensive month to fly from CAI to PTY. Avoiding peak travel times is often the key to better flight prices.
What is the cheapest airline that flies from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from CAI to PTY. Then, sort your results by "Price (lowest to highest)" to score a good deal.
How many flights per day from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)?
Direct flights from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from CAI to PTY?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)?
To touch down at Tocumen Intl. Airport (PTY) on schedule, choose a flight that takes off from Cairo Intl. Airport (CAI) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY) last-minute?
Waiting until just before your departure to book your flight from CAI to PTY often results in higher prices. While you may find some last-minute deals, they aren't always guaranteed. Allow some flexibility in your schedule to maximize your chances of scoring a bargain.
Is it cheaper to book a CAI to PTY flight and hotel package?
You'll typically save money by booking a CAI to PTY flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After selecting your ideal accommodations and flights, you can add extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)?
It's usually possible to cancel or reschedule your CAI to PTY flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Cairo Intl.
Destination airport
Tocumen Intl.
Airlines serving
Air France, American Airlines, Emirates, Iberia, KLM, United
Roundtrip price
$871
Distance
7112 mi

Book with confidence

Cairo to Panama City Flights

The cheapest times to fly from Cairo to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cairo to Panama City are during the month of March. You can find some of the cheapest flights from Cairo to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cairo to Panama City

Sunday is one of the best days to book for cheap flights from Cairo to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cairo to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cairo to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $559 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cairo to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cairo to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Cairo to Panama City Flights

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*Available to One Key members.