$1,195 Cheap Flights from Columbus (CMH) to São Tomé Island (TMS)

View $1,195 flight on Wed, Nov 12, 2025Opens in a new window

Popular airlines from John Glenn Columbus Intl. Airport (CMH) to São Tomé Island (TMS-São Tomé Intl.)

Cheap Flights from Columbus to São Tomé Island (CMH-TMS)

Prices were available within the past 7 days and start at $1,195 for one-way flights and $1,563 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Jan 20 - Sun, Feb 8
CMH
Columbus
TMS
São Tomé Island
$1,563 Roundtrip, found 3 days ago
$1,563
Roundtrip
found 3 days ago
Select United flight, departing Tue, Jan 20 from Columbus to São Tomé Island, returning Sun, Feb 8, priced at $1,563 found 3 days ago
Air Canada
Fri, Jan 16 - Sun, Feb 1
CMH
Columbus
TMS
São Tomé Island
$1,565 Roundtrip, found 3 days ago
$1,565
Roundtrip
found 3 days ago
Select Air Canada flight, departing Fri, Jan 16 from Columbus to São Tomé Island, returning Sun, Feb 1, priced at $1,565 found 3 days ago
Lufthansa
Sat, Nov 29 - Sat, Dec 6
CMH
Columbus
TMS
São Tomé Island
$1,566 Roundtrip, found 1 day ago
$1,566
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Sat, Nov 29 from Columbus to São Tomé Island, returning Sat, Dec 6, priced at $1,566 found 1 day ago
Air Canada
Fri, Jan 16 - Wed, Jan 28
CMH
Columbus
TMS
São Tomé Island
$1,568 Roundtrip, found 3 days ago
$1,568
Roundtrip
found 3 days ago
Select Air Canada flight, departing Fri, Jan 16 from Columbus to São Tomé Island, returning Wed, Jan 28, priced at $1,568 found 3 days ago
United
Mon, Jan 12 - Wed, Jan 28
CMH
Columbus
TMS
São Tomé Island
$1,573 Roundtrip, found 3 days ago
$1,573
Roundtrip
found 3 days ago
Select United flight, departing Mon, Jan 12 from Columbus to São Tomé Island, returning Wed, Jan 28, priced at $1,573 found 3 days ago
United
Mon, Jan 26 - Sun, Feb 15
CMH
Columbus
TMS
São Tomé Island
$1,575 Roundtrip, found 3 days ago
$1,575
Roundtrip
found 3 days ago
Select United flight, departing Mon, Jan 26 from Columbus to São Tomé Island, returning Sun, Feb 15, priced at $1,575 found 3 days ago
Lufthansa
Sat, Nov 29 - Sat, Dec 6
CMH
Columbus
TMS
São Tomé Island
$1,642 Roundtrip, found 1 day ago
$1,642
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Sat, Nov 29 from Columbus to São Tomé Island, returning Sat, Dec 6, priced at $1,642 found 1 day ago
Air Canada
Fri, Nov 14 - Sun, Nov 16
CMH
Columbus
TMS
São Tomé Island
$1,645 Roundtrip, found 4 days ago
$1,645
Roundtrip
found 4 days ago
Select Air Canada flight, departing Fri, Nov 14 from Columbus to São Tomé Island, returning Sun, Nov 16, priced at $1,645 found 4 days ago
United
Thu, Jan 8 - Fri, Jan 23
CMH
Columbus
TMS
São Tomé Island
$1,646 Roundtrip, found 3 days ago
$1,646
Roundtrip
found 3 days ago
Select United flight, departing Thu, Jan 8 from Columbus to São Tomé Island, returning Fri, Jan 23, priced at $1,646 found 3 days ago
Ethiopian Airlines
Wed, Nov 12 - Wed, Nov 19
CMH
Columbus
TMS
São Tomé Island
$2,158 Roundtrip, found 4 days ago
$2,158
Roundtrip
found 4 days ago
Select Ethiopian Airlines flight, departing Wed, Nov 12 from Columbus to São Tomé Island, returning Wed, Nov 19, priced at $2,158 found 4 days ago

Frequently asked questions

How much does a flight from John Glenn Columbus Intl. Airport (CMH) to Sao Tome Intl. Airport (TMS) cost?
Secure a cheap one-way flight from $1,195 or cheap return flight from $1,563 from John Glenn Columbus Intl. Airport (CMH) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from John Glenn Columbus Intl. Airport (CMH) to Sao Tome Intl. Airport (TMS)?
Planning your getaway for January is a great way to save, as it's the cheapest month for flights between CMH and TMS. You'll usually find the lowest prices during off-peak months.
What is the cheapest airline that flies from John Glenn Columbus Intl. Airport (CMH) to Sao Tome Intl. Airport (TMS)?
To find the cheapest airline that'll fly you from CMH to TMS, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from John Glenn Columbus Intl. Airport (CMH) to Sao Tome Intl. Airport (TMS)?
There aren't any daily direct flights available from John Glenn Columbus Intl. Airport (CMH) to Sao Tome Intl. Airport (TMS). But you can book flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be on your way before you know it.
What day of the week has the most flights from CMH to TMS?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can vary based on a number of factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from John Glenn Columbus Intl. Airport (CMH) to Sao Tome Intl. Airport (TMS)?
Opt for a flight from John Glenn Columbus Intl. Airport (CMH) to Sao Tome Intl. Airport (TMS) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from John Glenn Columbus Intl. Airport (CMH) to Sao Tome Intl. Airport (TMS) last-minute?
Booking your flight from CMH to TMS right before your getaway is usually more expensive. But if there's some wiggle room with your departure dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a CMH to TMS flight and hotel package?
Compared with arranging flights and hotels separately, booking a CMH to TMS flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place will take the hassle out of travel planning. Simply secure your flights and select from our wide range of hotels, then tailor your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from John Glenn Columbus Intl. Airport (CMH) to Sao Tome Intl. Airport (TMS)?
Typically, you can cancel or reschedule your CMH to TMS flight. However, there may be additional fees, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you want more information, head to our Customer Service portal.

Travel information

Origin airport
John Glenn Columbus Intl.
Destination airport
São Tomé Intl.
Roundtrip price
$1,562
Distance
6180 mi

Book with confidence

Columbus to São Tomé Island Flights

The cheapest times to fly from Columbus to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbus to São Tomé Island are during the month of January. You can find some of the cheapest flights from Columbus to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Columbus to São Tomé Island

Sunday is one of the best days to book for cheap flights from Columbus to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Columbus to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbus to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from $1,195 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbus to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbus to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Columbus to São Tomé Island Flights
*Available to One Key members.