$347 Cheap Flights from Lisbon (LIS) to São Tomé Island (TMS)

View $347 flight on Tue, Oct 7, 2025Opens in a new window

Popular airlines from Humberto Delgado Airport (LIS) to São Tomé Island (TMS-São Tomé Intl.)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Lisbon to São Tomé Island (LIS-TMS)

Prices were available within the past 7 days and start at $347 for one-way flights and $535 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

TAAG Angola Airlines
Sun, Oct 19 - Mon, Nov 3
LIS
Lisbon
TMS
São Tomé Island
$535 Roundtrip, found 3 days ago
$535
Roundtrip
found 3 days ago
Select TAAG Angola Airlines flight, departing Sun, Oct 19 from Lisbon to São Tomé Island, returning Mon, Nov 3, priced at $535 found 3 days ago
TAAG Angola Airlines
Thu, Nov 6 - Mon, Nov 24
LIS
Lisbon
TMS
São Tomé Island
$545 Roundtrip, found 1 day ago
$545
Roundtrip
found 1 day ago
Select TAAG Angola Airlines flight, departing Thu, Nov 6 from Lisbon to São Tomé Island, returning Mon, Nov 24, priced at $545 found 1 day ago
TAAG Angola Airlines
Thu, Dec 4 - Wed, Dec 31
LIS
Lisbon
TMS
São Tomé Island
$546 Roundtrip, found 6 days ago
$546
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Thu, Dec 4 from Lisbon to São Tomé Island, returning Wed, Dec 31, priced at $546 found 6 days ago
TAAG Angola Airlines
Sun, Nov 30 - Wed, Dec 3
LIS
Lisbon
TMS
São Tomé Island
$555 Roundtrip, found 5 hours ago
$555
Roundtrip
found 5 hours ago
Select TAAG Angola Airlines flight, departing Sun, Nov 30 from Lisbon to São Tomé Island, returning Wed, Dec 3, priced at $555 found 5 hours ago
TAAG Angola Airlines
Tue, Oct 7 - Mon, Oct 13
LIS
Lisbon
TMS
São Tomé Island
$575 Roundtrip, found 1 day ago
$575
Roundtrip
found 1 day ago
Select TAAG Angola Airlines flight, departing Tue, Oct 7 from Lisbon to São Tomé Island, returning Mon, Oct 13, priced at $575 found 1 day ago
TAAG Angola Airlines
Sun, Nov 30 - Fri, Dec 26
LIS
Lisbon
TMS
São Tomé Island
$576 Roundtrip, found 6 days ago
$576
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Sun, Nov 30 from Lisbon to São Tomé Island, returning Fri, Dec 26, priced at $576 found 6 days ago
TAAG Angola Airlines
Sun, Dec 7 - Fri, Dec 26
LIS
Lisbon
TMS
São Tomé Island
$585 Roundtrip, found 6 days ago
$585
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Sun, Dec 7 from Lisbon to São Tomé Island, returning Fri, Dec 26, priced at $585 found 6 days ago
TAAG Angola Airlines
Thu, Dec 11 - Fri, Dec 26
LIS
Lisbon
TMS
São Tomé Island
$616 Roundtrip, found 6 days ago
$616
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Thu, Dec 11 from Lisbon to São Tomé Island, returning Fri, Dec 26, priced at $616 found 6 days ago
TAAG Angola Airlines
Sun, Oct 12 - Mon, Oct 27
LIS
Lisbon
TMS
São Tomé Island
$617 Roundtrip, found 1 day ago
$617
Roundtrip
found 1 day ago
Select TAAG Angola Airlines flight, departing Sun, Oct 12 from Lisbon to São Tomé Island, returning Mon, Oct 27, priced at $617 found 1 day ago
TAP Portugal
Fri, Nov 7 - Sun, Nov 23
LIS
Lisbon
TMS
São Tomé Island
$666 Roundtrip, found 1 day ago
$666
Roundtrip
found 1 day ago
Select TAP Portugal flight, departing Fri, Nov 7 from Lisbon to São Tomé Island, returning Sun, Nov 23, priced at $666 found 1 day ago

Frequently asked questions

How much does a flight from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS) cost?
Lock in a cheap one-way flight from $347 or cheap return flight from $535 from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS)?
October is the least expensive month to fly from LIS to TMS. Traveling during an off-peak travel window is often the key to better flight prices.
Which airlines fly direct from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS)?
You can fly directly from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS) on a TAP Portugal flight.
What is the cheapest airline that flies from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS)?
The cheapest airline to offer flights between Humberto Delgado Airport (LIS) and Sao Tome Intl. Airport (TMS) can change depending on your travel dates. STP Airways and TAP Portugal are just some of the choices offering reasonable prices. Use Expedia's filters to compare airlines in one place and find the right LIS to TMS flight for your budget.
How many flights per day from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS)?
On average you can take your pick of 2 direct flights every week from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS). To increase your travel options, consider taking a flight with a layover. Enter your dates on Expedia and then filter your search to include one stop or more.
What are the most popular departure times for flights from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS)?
More passengers fly between LIS and TMS at 12 AM than at any other point in the day. Rather go when it's quieter? Pick a flight outside the busiest times and you could save on your fare as well.
What day of the week has the most flights from LIS to TMS?
If you fly on a Saturday, you'll get the largest range of options for flights from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS).
What is the earliest flight from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS)?
The earliest flight leaving from Humberto Delgado Airport (LIS) is at around 12:05AM UTC+0. Catch this flight and you'll land at Sao Tome Intl. Airport (TMS) at approximately 6:20AM UTC+0. The entire trip takes 6h 15m.
How long does it take to fly from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS)?
The average flight time from LIS to TMS is 6 hours and 25 minutes, covering a distance of 2,800 mi.
What airline has the least delays from LIS to TMS?
With 87% of journeys typically landing on time, STP Airways has the best on-time performance for direct flights from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS). To monitor your flight status and receive notifications if anything changes, head to the Expedia App.
What is the best time to fly from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS)?
Opt for a flight from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for São Tomé Island from Humberto Delgado Airport (LIS)?
If you're traveling on a direct flight from Humberto Delgado Airport (LIS) to São Tomé Island, Sao Tome Intl. Airport (TMS) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS) last-minute?
Waiting until right before your break to book a ticket from LIS to TMS generally means paying more. While you may come across some last-minute deals, they aren't always guaranteed. Keep your travel plans flexible to boost your chances of getting a bargain.
Is it cheaper to book a LIS to TMS flight and hotel package?
Compared with arranging flights and hotels separately, booking a LIS to TMS flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one convenient place takes the hassle out of planning your trip. Just secure your flights and select from our wide range of hotels, then tailor your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Humberto Delgado Airport (LIS) to Sao Tome Intl. Airport (TMS)?
If you reserved your LIS to TMS flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more details.

Travel information

Travel information

Origin airport
Humberto Delgado
Destination airport
São Tomé Intl.
Airlines serving
TAAG Angola Airlines, TAP Portugal
Roundtrip price
$535
Distance
2836 mi
Average flight time
6 hours 6 mins

Book with confidence

Book with confidence

Lisbon to São Tomé Island Flights

The cheapest times to fly from Lisbon to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lisbon to São Tomé Island are during the month of October. You can find some of the cheapest flights from Lisbon to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lisbon to São Tomé Island

Sunday is one of the best days to book for cheap flights from Lisbon to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lisbon to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lisbon to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from $347 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lisbon to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lisbon to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Lisbon to São Tomé Island Flights
*Available to One Key members.