$341 Cheap Flights from Mexico City (MEX) to Greenville (GSP)

View $341 flight on Fri, Sep 26, 2025Opens in a new window

Popular airlines from Benito Juarez International Airport (MEX) to Greenville-Spartanburg Intl. Airport (GSP)

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Cheap Flights from Mexico City to Greenville (MEX-GSP)

Prices were available within the past 7 days and start at $341 for one-way flights and $500 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Mon, Sep 22 - Tue, Sep 23
MEX
Mexico City
GSP
Greenville
$500 Roundtrip, found 2 days ago
$500
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Mon, Sep 22 from Mexico City to Greenville, returning Tue, Sep 23, priced at $500 found 2 days ago
Delta
Mon, Sep 22 - Tue, Sep 23
MEX
Mexico City
GSP
Greenville
$500 Roundtrip, found 2 days ago
$500
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Sep 22 from Mexico City to Greenville, returning Tue, Sep 23, priced at $500 found 2 days ago
Delta
Mon, Sep 22 - Tue, Sep 23
MEX
Mexico City
GSP
Greenville
$539 Roundtrip, found 2 days ago
$539
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Sep 22 from Mexico City to Greenville, returning Tue, Sep 23, priced at $539 found 2 days ago
Aeromexico
Mon, Sep 22 - Tue, Sep 23
MEX
Mexico City
GSP
Greenville
$547 Roundtrip, found 2 days ago
$547
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Mon, Sep 22 from Mexico City to Greenville, returning Tue, Sep 23, priced at $547 found 2 days ago
Delta
Wed, Jun 10 - Thu, Jun 11
MEX
Mexico City
GSP
Greenville
$552 Roundtrip, found 5 days ago
$552
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Jun 10 from Mexico City to Greenville, returning Thu, Jun 11, priced at $552 found 5 days ago
American Airlines
Fri, Oct 3 - Tue, Oct 7
MEX
Mexico City
GSP
Greenville
$555 Roundtrip, found 23 hours ago
$555
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Fri, Oct 3 from Mexico City to Greenville, returning Tue, Oct 7, priced at $555 found 23 hours ago
United
Mon, Nov 10 - Mon, Nov 24
MEX
Mexico City
GSP
Greenville
$555 Roundtrip, found 2 hours ago
$555
Roundtrip
found 2 hours ago
Select United flight, departing Mon, Nov 10 from Mexico City to Greenville, returning Mon, Nov 24, priced at $555 found 2 hours ago
United
Thu, Sep 25 - Mon, Mar 2
MEX
Mexico City
GSP
Greenville
$556 Roundtrip, found 19 hours ago
$556
Roundtrip
found 19 hours ago
Select United flight, departing Thu, Sep 25 from Mexico City to Greenville, returning Mon, Mar 2, priced at $556 found 19 hours ago
Aeromexico
Tue, Sep 23 - Wed, Sep 24
MEX
Mexico City
GSP
Greenville
$558 Roundtrip, found 15 hours ago
$558
Roundtrip
found 15 hours ago
Select Aeromexico flight, departing Tue, Sep 23 from Mexico City to Greenville, returning Wed, Sep 24, priced at $558 found 15 hours ago
Air Canada
Tue, Sep 23 - Wed, Jan 21
MEX
Mexico City
GSP
Greenville
$1,157 Roundtrip, found 20 hours ago
$1,157
Roundtrip
found 20 hours ago
Select Air Canada flight, departing Tue, Sep 23 from Mexico City to Greenville, returning Wed, Jan 21, priced at $1,157 found 20 hours ago

Find the cheapest month to fly from Mexico City (MEX) to Greenville (GSP)

May is typically the cheapest month to fly

From $432 - $672 per traveler.

Graph displaying average flight prices per month

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $689
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $689
Flights from Mexico City (MEX) to Greenville (GSP)
Origin airport
Mexico City Intl.
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
Aeromexico, Air Canada, American Airlines, Delta, United
Roundtrip price
$499
Distance
1483 mi

Mexico City to Greenville Flights

The cheapest times to fly from Mexico City to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mexico City to Greenville are during the month of September. You can find some of the cheapest flights from Mexico City to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mexico City to Greenville

Sunday is one of the best days to book for cheap flights from Mexico City to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mexico City to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mexico City to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $341 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mexico City to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mexico City to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Mexico City Intl. Airport (MEX) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Snag a cheap one-way flight from $341 or cheap return flight from $500 from Mexico City Intl. Airport (MEX) to Greenville-Spartanburg Intl. Airport (GSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Mexico City Intl. Airport (MEX) to Greenville-Spartanburg Intl. Airport (GSP)?
September is the most affordable month to fly from MEX to GSP. Avoiding peak travel times is often the key to finding a great deal.
What is the cheapest airline that flies from Mexico City Intl. Airport (MEX) to Greenville-Spartanburg Intl. Airport (GSP)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll take you from MEX to GSP. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from Mexico City Intl. Airport (MEX) to Greenville-Spartanburg Intl. Airport (GSP)?
There aren't any daily nonstop flights available from Mexico City Intl. Airport (MEX) to Greenville-Spartanburg Intl. Airport (GSP). But you can choose flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from MEX to GSP?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mexico City Intl. Airport (MEX) to Greenville-Spartanburg Intl. Airport (GSP)?
To avoid potential delays on the Mexico City Intl. Airport (MEX) to Greenville-Spartanburg Intl. Airport (GSP) route, aim to fly before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mexico City Intl. Airport (MEX) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Waiting until just before your trip to book a flight from MEX to GSP often results in higher prices. While it's possible to find some last-minute discounts, they aren't always guaranteed. Be flexible with your itinerary to maximize your chances of snagging a bargain.
Is it cheaper to book a MEX to GSP flight and hotel package?
Securing a MEX to GSP flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Choose from our wide range of accommodations and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mexico City Intl. Airport (MEX) to Greenville-Spartanburg Intl. Airport (GSP)?
It's usually possible to cancel or reschedule your MEX to GSP flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.