$399 Cheap Flights from Myrtle Beach (MYR) to Madrid (MAD)

View $399 flight on Tue, Dec 2, 2025Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Adolfo Suarez Madrid-Barajas Airport (MAD)

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Cheap Flights from Myrtle Beach to Madrid (MYR-MAD)

Prices were available within the past 7 days and start at $399 for one-way flights and $438 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Dec 2 - Tue, Dec 16
MYR
Myrtle Beach
MAD
Madrid
$438 Roundtrip, found 16 hours ago
$438
Roundtrip
found 16 hours ago
Select Delta flight, departing Tue, Dec 2 from Myrtle Beach to Madrid, returning Tue, Dec 16, priced at $438 found 16 hours ago
Virgin Atlantic
Tue, Dec 2 - Tue, Dec 16
MYR
Myrtle Beach
MAD
Madrid
$438 Roundtrip, found 16 hours ago
$438
Roundtrip
found 16 hours ago
Select Virgin Atlantic flight, departing Tue, Dec 2 from Myrtle Beach to Madrid, returning Tue, Dec 16, priced at $438 found 16 hours ago
Delta
Tue, Dec 2 - Tue, Dec 16
MYR
Myrtle Beach
MAD
Madrid
$438 Roundtrip, found 16 hours ago
$438
Roundtrip
found 16 hours ago
Select Delta flight, departing Tue, Dec 2 from Myrtle Beach to Madrid, returning Tue, Dec 16, priced at $438 found 16 hours ago
Delta
Mon, Dec 29 - Thu, Jan 15
MYR
Myrtle Beach
MAD
Madrid
$443 Roundtrip, found 1 day ago
$443
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Dec 29 from Myrtle Beach to Madrid, returning Thu, Jan 15, priced at $443 found 1 day ago
Delta
Wed, Dec 31 - Wed, Jan 14
MYR
Myrtle Beach
MAD
Madrid
$462 Roundtrip, found 1 day ago
$462
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Dec 31 from Myrtle Beach to Madrid, returning Wed, Jan 14, priced at $462 found 1 day ago
Delta
Tue, Dec 2 - Tue, Dec 16
MYR
Myrtle Beach
MAD
Madrid
$464 Roundtrip, found 16 hours ago
$464
Roundtrip
found 16 hours ago
Select Delta flight, departing Tue, Dec 2 from Myrtle Beach to Madrid, returning Tue, Dec 16, priced at $464 found 16 hours ago
Delta
Mon, Dec 29 - Wed, Jan 14
MYR
Myrtle Beach
MAD
Madrid
$466 Roundtrip, found 1 day ago
$466
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Dec 29 from Myrtle Beach to Madrid, returning Wed, Jan 14, priced at $466 found 1 day ago
KLM
Tue, Dec 2 - Tue, Dec 16
MYR
Myrtle Beach
MAD
Madrid
$490 Roundtrip, found 16 hours ago
$490
Roundtrip
found 16 hours ago
Select KLM flight, departing Tue, Dec 2 from Myrtle Beach to Madrid, returning Tue, Dec 16, priced at $490 found 16 hours ago
United
Tue, Dec 2 - Tue, Dec 16
MYR
Myrtle Beach
MAD
Madrid
$493 Roundtrip, found 16 hours ago
$493
Roundtrip
found 16 hours ago
Select United flight, departing Tue, Dec 2 from Myrtle Beach to Madrid, returning Tue, Dec 16, priced at $493 found 16 hours ago
Air France
Tue, Dec 2 - Tue, Dec 16
MYR
Myrtle Beach
MAD
Madrid
$509 Roundtrip, found 16 hours ago
$509
Roundtrip
found 16 hours ago
Select Air France flight, departing Tue, Dec 2 from Myrtle Beach to Madrid, returning Tue, Dec 16, priced at $509 found 16 hours ago

Alternative airports near Madrid

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Adolfo Suarez Madrid-Barajas MAD. Cheapest and Closest option available. Average driving time to city center is 20 minutes. Flights from $637
MAD
Adolfo Suarez Madrid-Barajas
CheapestClosest
Average driving time to city center20 min
Flights from $637

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Adolfo Suarez Madrid-Barajas Airport (MAD) cost?
Snag a cheap one-way flight from $399 or cheap return flight from $438 from Myrtle Beach Intl. Airport (MYR) to Adolfo Suarez Madrid-Barajas Airport (MAD) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Myrtle Beach Intl. Airport (MYR) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
December is the cheapest month to fly from MYR to MAD. Planning your trip for the off-season is often the key to scoring lower fares.
What is the cheapest airline that flies from Myrtle Beach Intl. Airport (MYR) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll fly you from MYR to MAD. Then, sort your results by "Price (lowest to highest)" to pick up a great deal.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
There are no daily direct flights from Myrtle Beach Intl. Airport (MYR) to Adolfo Suarez Madrid-Barajas Airport (MAD). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from MYR to MAD?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change depending on a range of factors, such as the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
To land at Adolfo Suarez Madrid-Barajas Airport (MAD) on schedule, choose a flight that leaves Myrtle Beach Intl. Airport (MYR) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Adolfo Suarez Madrid-Barajas Airport (MAD) last-minute?
Last-minute fares from MYR to MAD are typically more expensive. To lock in the cheapest rates, start searching for flights as early as possible. That said, if you're flexible with your travel plans, you may score a cheap ticket right before your trip.
Is it cheaper to book a MYR to MAD flight and hotel package?
Booking a MYR to MAD flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Select from our impressive range of stays and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
Typically, it's possible to cancel or reschedule your MYR to MAD flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Myrtle Beach Intl.
Destination airport
Adolfo Suárez Madrid-Barajas
Airlines serving
Air Canada, Air France, American Airlines, British Airways, Delta, KLM, Scandinavian Airlines, United, Virgin Atlantic
Roundtrip price
$438
Distance
4053 mi

Book with confidence

Myrtle Beach to Madrid Flights

The cheapest times to fly from Myrtle Beach to Madrid

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Madrid are during the month of December. You can find some of the cheapest flights from Myrtle Beach to Madrid with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Madrid

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Madrid: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Madrid

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Madrid in 2025. You can also book with separate airlines for your outbound and return journeys, from $399 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Madrid flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Madrid airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Myrtle Beach to Madrid Flights

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*Available to One Key members.