Find 4 Star Hotels in Brussels, IL from $110
Upfront pricing
Treat yourself
Be picky
Check availability on Brussels 4 Star Hotels
Compare Brussels 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

DoubleTree by Hilton St. Louis Airport

Renaissance St. Louis Airport Hotel

Ameristar Casino Resort and Spa

Marriott St. Louis Airport

DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton Hotel St. Louis - Chesterfield

Historic Main Street Heritage Retreat

Beall Mansion An Elegant Bed & Breakfast Inn
Top Brussels Hotel Reviews

Renaissance St. Louis Airport Hotel

DoubleTree by Hilton St. Louis Airport
Find out more about Brussels
Brussels Four Star Hotel Information
When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Brussels, Illinois are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Brussels 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.
Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Brussels. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Brussels, Illinois, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.
Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Brussels hotels offer everything your heart desires.
Frequently asked questions
Explore a world of travel with Expedia
- Vacation Homes in Golden Eagle
- Cabin Rentals in Golden Eagle
- Batchtown Hotels
- 4 Star Hotels in Grafton
- 5 Star Hotels in Grafton
- Grafton Hotels
- B&B in Grafton
- Cabin Rentals in Grafton
- Resorts & Hotels with Spas in Grafton
- Treehouses in Grafton
- Hotels with Hot Tubs in Grafton
- Hotels with an Outdoor Pool in Grafton
- Condo Rentals in Grafton
- Hotels with an Indoor Pool in Grafton
- Accor Hotels in Grafton
- Motels in Grafton
- Historic Hotels in Grafton
- Cottages in Grafton
- Hilton Hotels in Grafton
- Apartments in Grafton
- Hotels with a Pool in Grafton
- Romantic Hotels in Grafton
- Vacation Homes in Grafton
- Luxury Hotels in Grafton
- Best Western Hotels in Grafton
- Wyndham Hotels in Grafton
- Casino Hotels in Grafton
- Hotels near Grafton Ice Cream Company
- Hotels near Raging Rivers Waterpark
- Fieldon Hotels
- Vacation Homes in Fieldon
- Cottages in Fieldon
- Elsah Hotels
- B&B in Elsah
- Cabin Rentals in Elsah
- Honeymoon Resorts & in Elsah
- Resorts & Hotels with Spas in Elsah
- Vacation Homes in Elsah
- Hotel Wedding Venues Hotels in Elsah
- Hotels near Treehouse Wildlife Center
- 5 Star Hotels in Dow
- Dow Hotels
- Cabin Rentals in Dow
- Hardin Hotels
- Hotels near Westlake Golf Course
- Hotels near Jerseyville Historic District
- Jerseyville Hotels
- Hotels near Cheney Mansion
- Hotels near Jersey County Historical Society
- Pet-friendly Hotels in Jerseyville
- B&B in Jerseyville
- Cabin Rentals in Jerseyville
- Motels in Jerseyville
- Vacation Homes in Jerseyville
- Hotels near American Legion Fairgrounds
- 4 Star Hotels in Godfrey
- 5 Star Hotels in Godfrey
- Car rentals near Golden Eagle
- Car rentals near Rosedale
- Enterprise Rental Cars in Grafton
- Car rentals near Grafton
- Car rentals in Enterprise 2920 N Aspen Ave
- Hertz Rental Cars in Grafton
- Budget Rental Cars in Grafton
- Car rentals near Chautauqua
- Car rentals near Fieldon
- Car rentals near Elsah
- Car rentals near Otterville
- Car rentals near Dow
- Car rentals near Jerseyville
- Car rentals near American Legion Fairgrounds
- Car rentals near Hamburg
- Car rentals near Kane
























