Find hotels in East Main Street, Grand Junction from $72
Go beyond your typical stay in East Main Street
Pet friendly
Family friendly
Check prices for these dates
Discover 572 East Main Street hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for East Main Street hotels
Camp Eddy
Camp Eddy
9.4 out of 10, Exceptional, (247)
$147 nightly
The price is $169
Aug 28 - Aug 29
Total with taxes and fees
Best Western Grande River Inn & Suites
Best Western Grande River Inn & Suites
9.0 out of 10, Wonderful, (737)
$127 nightly
The price is $133
Sep 3 - Sep 4
Total with taxes and fees
Super 8 by Wyndham Fruita
Super 8 by Wyndham Fruita
8.6 out of 10, Excellent, (1013)
$74 nightly
The price is $85
Sep 1 - Sep 2
Total with taxes and fees
Ramada by Wyndham Grand Junction
Ramada by Wyndham Grand Junction
8.4 out of 10, Very Good, (1710)
$73 nightly
The price is $84
Aug 31 - Sep 1
Total with taxes and fees
Grand Vista Hotel
Grand Vista Hotel
8.2 out of 10, Very Good, (3286)
$76 nightly
The price is $87
Sep 2 - Sep 3
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Fruita
La Quinta Inn & Suites by Wyndham Fruita
8.4 out of 10, Very Good, (1001)
$109 nightly
The price is $125
Sep 1 - Sep 2
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in East Main Street
Find the best East Main Street areas and neighborhoods for the activities you enjoy most.
Downtown
1 out of top 10 points of interest in this area
While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.
Redlands
1 out of top 10 points of interest in this area
You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.
Pear Park
If you're spending some time in Pear Park, Colorado River and James M. Robb – Colorado River State Park are top sights worth seeing.
Horizon Drive District
While there might not be top attractions in Horizon Drive District, you can explore the larger area and discover places like Canyon View Park and Bananas Fun Park.
Orchard Mesa
1 out of top 10 points of interest in this area
If you're spending some time in Orchard Mesa, Mesa County Fairgrounds and Gunnison River are top sights worth seeing.
Top East Main Street Hotel Reviews
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Hotels in top Grand Junction neighborhoods
- Hotels in Downtown
- Hotels in Redlands
- Hotels in Pear Park
- Hotels in Horizon Drive District
- Hotels in Orchard Mesa
- Hotels in East Main Street
- Hotels in Fruitvale
- Hotels in 24 Road Corridor
- Hotels in Washington Park
- Hotels in 7th Street Historic District
- Hotels in Hawthorne Park
- Hotels in Lincoln Park Historic District
- Hotels in The Ridges
Hotels near popular Grand Junction Attractions
- Hotels near Colorado Mesa University
- Hotels near Colorado River
- Hotels near Colorado National Monument
- Hotels near Canyon View Park
- Hotels near Two Rivers Convention Center
- Hotels near Redlands Mesa Golf Club
- Hotels near Bananas Fun Park
- Hotels near Mesa County Fairgrounds
- Hotels near Gunnison River
- Hotels near Western Colorado Botanical Gardens
More Accommodation Types in East Main Street
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- Cottages in Grand Junction
- Condo Rentals in Grand Junction
- Cabin Rentals in Grand Junction
- Farmstay in Grand Junction
- Lodges in Grand Junction
- Motels in Grand Junction
- Guest Houses in Grand Junction
- Inns in Grand Junction
- RV Parks in Grand Junction
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- B&B in Grand Junction
Hotels Close to Nearby Airports
East Main Street Hotels by Star Rating
East Main Street Hotels by Brand
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