Grand Center Vacations from $309
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Your Grand Center Vacation
Book one of our vacation packages to Grand Center and experience the wonders of this interesting neighborhood. Especially renowned for its culture, your next awesome adventure can be found right here. Some popular nearby attractions to see during your trip to Grand Center include Busch Stadium, Gateway Arch and Dome at America’s Center. Don't just dream it — turn it into a reality! Reserve your ideal Grand Center vacation with Expedia and experience travel your way.
The Latest Grand Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Residence Inn by Marriott St Louis Downtown
Midtown
Price was $519, price is now $402 per person
$402
per person
Dec 3 - Dec 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
7.8/10 Good! (1,001 reviews)
The room was very clean, with no normal hotel mildew smell. The lack of smell was amazing, actually. The staff was super helpful and parking was gated with plenty of spots. We’d definitely be back! Thank you Marriot.
Reviewed on Nov 1, 2026
Where to stay in Grand Center
Find the best Grand Center areas and neighborhoods for the activities you enjoy most. Learn more about Grand Center
Downtown St. Louis
4 out of top 10 points of interest in this area
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Grand Center Hotel Deals
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $122 total per night from Nov 23 to Nov 24
$122 total
Nov 23 - Nov 24
Total with taxes and fees
8.8/10 Excellent! (1,172 reviews)
"A neat hotel with fun color rooms. It was nice to stay somewhere different from your basic cookie cutter hotel. However, our room was a little run down. You could see some decent wear and tear. The vanity sink drain emitted a bad smell when you ran the water. Seems like the drains need to be cleaned. ..."
Reviewed on Nov 1, 2026
White House at Grand Central
3805 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $151 total per night from Nov 3 to Nov 4
$151 total
Nov 3 - Nov 4
Total with taxes and fees
8.2/10 Very Good! (168 reviews)
"The location of this property is very nice and is conveniently located to most things you want to do. The apartment itself was not very well cleaned and specifically the bathroom was not cleaned from previous guests. We found previous guest hair and other items still in the tub and on the bathroom ..."
Reviewed on Oct 31, 2026
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $104 total per night from Nov 16 to Nov 17
$104 total
Nov 16 - Nov 17
Total with taxes and fees
9.4/10 Exceptional! (3,344 reviews)
"Beautiful hotel, right near the airport and I-70 but rooms were very quiet. Quickest check-in ever! Restaurant next door. Staff was exceptional."
Reviewed on Nov 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Grand Center attractions
Things to do
StL's Signature "Sights and Bites" - Private Tour in St. Louis
$175
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
$24
per adult
100% of travellers recommend
Self-Guided Audio Tour of Gateway Arch National Park & St. Louis
$15
per traveler
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.