Santa Maria

Guayaquil

Things to do

City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

$65
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

$122
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
Cocoa farm and Chocolate making!

Cocoa farm and Chocolate making!

$155
per adult
Cocoa farm and Chocolate making!
Private city tour in Guayaquil - Iguana Park

Guayaquil Private Experience - City Tour for Seniors

$170
per adult
Guayaquil Private Experience - City Tour for Seniors
Half Day Walking Tour of Guayaquil Pearl of the Pacific

Half Day Walking Tour of Guayaquil Pearl of the Pacific

$100
per adult
Half Day Walking Tour of Guayaquil Pearl of the Pacific
Guayaquil City Tour Including the Light House of Cerro Santa Ana

Guayaquil City Tour Including the Light House of Cerro Santa Ana

$140
per adult
Guayaquil City Tour Including the Light House of Cerro Santa Ana
See all activities in Guayaquil

Santa Maria Hotel Deals

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
$105 nightly
The price is $118 total per night from Nov 4 to Nov 5
$118 total
Nov 4 - Nov 5
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,005 reviews)
"We love the service and the hotel is modern and has good food and great drinks ."

Reviewed on Oct 26, 2026

Wyndham Guayaquil Puerto Santa Ana
Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111 Guayaquil
$98 nightly
The price is $110 total per night from Nov 22 to Nov 23
$110 total
Nov 22 - Nov 23
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,004 reviews)
"Improve cleaning."

Reviewed on Oct 26, 2026

Hilton Colon Guayaquil
Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
$89 nightly
The price is $100 total per night from Nov 1 to Nov 2
$100 total
Nov 1 - Nov 2
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (1,001 reviews)
"Very friendly staff, excellent breakfast, maintained and modern rooms. Was a great stay."

Reviewed on Oct 26, 2026

Oro Verde Guayaquil
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
$98 nightly
The price is $110 total per night from Nov 27 to Nov 28
$110 total
Nov 27 - Nov 28
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Holiday Inn Guayaquil Airport by IHG
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 out of 5
Juan Tanca Marengo Ave Guayaquil Guayas
$78 nightly
The price is $87 total per night from Oct 30 to Oct 31
$87 total
Oct 30 - Oct 31
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,000 reviews)
"Todo excelente, gran ubicación , precio justo, lo recomiendo"

Reviewed on Oct 27, 2026

Wyndham Garden Guayaquil
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4 out of 5
Clemente Ballén 406 Guayaquil Guayas
$60 nightly
The price is $69 total per night from Nov 28 to Nov 29
$69 total
Nov 28 - Nov 29
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...
Unipark by Oro Verde Hotels
See all 444 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

A colorful outdoor installation with large letters spelling out a word.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Artisan Market while you're in town.

A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and Numa Pompilio Llona Street while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

A lizard on a metal fence.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

A cityscape with a prominent skyscraper, a river, and a bridge.

Simón Bolívar

Simón Bolívar might not have many top sights, but Mall del Sol Shopping Center and San Marino Mall are two attractions nearby that you can check out.

Santa Maria

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