
Santa Maria Vacations from $315
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Your Santa Maria Vacation
Make planning your travels easy by reserving a vacation package to Santa Maria. Let us take care of all the details, so you can focus on appreciating everything this neighborhood has to offer. Can't wait to head out and see the sights during your trip to Santa Maria? Make sure you stop by nearby attractions like Banco Pichincha Monumental Stadium, Mall del Sol Commercial Center and San Marino Mall. Expedia will help you turn your ideal Santa Maria vacation into reality, no matter your travel plans or budget.
The Latest Santa Maria Vacation Packages

Hotel Boutique Santa Lucia
Reviewed on Mar 20, 2026

Mantahost Hotel
Reviewed on Mar 6, 2026


Balandra Hotel
Reviewed on Nov 25, 2025
Where to stay in Santa Maria

Ecuador
Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.
Santa Maria Hotel Deals

Wyndham Guayaquil Puerto Santa Ana
This place was great, service was top notch, they have won several prestigious hotel awards, and you can tell why the best service at a hotel I have experienced in a very long time.
Reviewed on Apr 11, 2026

Holiday Inn Guayaquil Airport by IHG
Staff was very nice
Reviewed on Apr 9, 2026

Oro Verde Guayaquil
Yes, great
Reviewed on Apr 10, 2026
Discover the most popular places to visit in Santa Maria

Malecon 2000
Malecon 2000 is just one of the places to see in Guayaquil, so why not enjoy the other things to explore during your travels? While you're in the area, find time to visit its shops.

City Mall
During your visit to Guayaquil, you can do some window-shopping at City Mall. Visit the area's cathedral, or simply enjoy its seafood restaurants.

Santa Ana Hill
Explore the great outdoors at Santa Ana Hill, a lovely green space in Guayaquil. While you're in the area, find time to visit its shops.
Things to do

Wine Tasting Experience with Tasting Menu

























