
Santa Maria Vacations from $282
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Your Santa Maria Vacation
Make planning your travels easy by reserving a vacation package to Santa Maria. Let us take care of all the details, so you can focus on appreciating everything this neighborhood has to offer. Can't wait to head out and see the sights during your trip to Santa Maria? Make sure you stop by nearby attractions like Banco Pichincha Monumental Stadium, Mall del Sol Commercial Center and San Marino Mall. Expedia will help you turn your ideal Santa Maria vacation into reality, no matter your travel plans or budget.
The Latest Santa Maria Vacation Packages


Hotel Rio Guayas
Reviewed on Jul 30, 2025

Luxury Suites Riverfront GYE
Reviewed on Aug 21, 2025

Hillary Nature Resort Spa
Reviewed on May 4, 2025

Oro Verde Guayaquil
Reviewed on Sep 4, 2025
Where to stay in Santa Maria

Downtown Guayaquil
Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.
Santa Maria Hotel Deals

Oro Verde Guayaquil

Holiday Inn Guayaquil Airport by IHG

Wyndham Garden Guayaquil
Discover the most popular places to visit in Santa Maria

Malecon 2000
Malecon 2000 is just one of the places to see in Guayaquil, so why not enjoy the other things to explore during your travels? While you're in the area, find time to visit its shops.

Santa Ana Hill
Explore the great outdoors at Santa Ana Hill, a lovely green space in Guayaquil. While you're in the area, find time to visit its shops.
U.S. Consulate General
U.S. Consulate General is just one of the places to see in San Eduardo, so why not enjoy the other things to explore during your travels? While you're in the area, find time to visit its shops.
Things to do

Small Group Guayaquil and Cocoa Farm Full-Day Tour
