Irene Vacation Rentals

Check prices for these dates

In two weeks
Nov 20 - Nov 22
In two months
Jan 1 - Jan 3
In three months
Jan 29 - Jan 31
In four months
Feb 26 - Feb 28

Our top choices for Irene vacation rentals

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1. Parkview Cottage ~ Charming Tiny Home ~ Queen Bed!

Parkview Cottage ~ Charming Tiny Home ~ Queen Bed!
Viborg
9.8 out of 10, Exceptional, (24 reviews)
"Very nice place to stay"
United States
Carrie B.
$88 nightly
The price is $94
Nov 9 - Nov 10
Total with taxes and fees
Parkview Cottage ~ Charming Tiny Home ~ Queen Bed!
A balcony with a metal table and chairs, overlooking a park with trees and a lake.

2. Downtown Yankton Apartment w/ Patio & River View!

Downtown Yankton Apartment w/ Patio & River View!
Yankton
9.2 out of 10, Wonderful, (34 reviews)
"Great location excellent water pressure in the shower. Great views"
United States
Steven F.
$271 nightly
The price is $294
Dec 6 - Dec 7
Total with taxes and fees
Downtown Yankton Apartment w/ Patio & River View!
A modern kitchen with a marble countertop, wooden cabinets, and pendant lighting.

3. Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!

Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!
Yankton
10.0 out of 10, Exceptional, (25 reviews)
"Beautiful house. Very cozy. Had a great stay."
United States
Tom S.
$770 nightly
The price is $812
Nov 9 - Nov 10
Total with taxes and fees
Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!
A balcony with a metal table and chairs, overlooking a park with trees and a lake.

4. Downtown Yankton Apartment w/ Patio & River View!

Downtown Yankton Apartment w/ Patio & River View!
3.0 star property
Yankton
$291 nightly
The price is $316
Dec 6 - Dec 7
Total with taxes and fees
Downtown Yankton Apartment w/ Patio & River View!
A modern two-story house with a balcony, large windows, and a stone facade.

5. Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
Crofton
10.0 out of 10, Exceptional, (11 reviews)
"Lots of room! Friendly Host!"
United States
Joy F.
$1,003 nightly
The price is $1,108
Nov 9 - Nov 10
Total with taxes and fees
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Irene Hotel Reviews

A modern living room with a fireplace, seating area, and large windows.
Fairfield Inn & Suites by Marriott Yankton

Fairfield Inn & Suites by Marriott Yankton

Fairfield Inn & Suites by Marriott Yankton
Yankton

10/10 Excellent

The staff was amazingly nice and helpful!!!! Would have given 10 stars for service if I could.
United States
Heidi
Reviewed October 29, 2026
Fairfield Inn & Suites by Marriott Yankton

Find out more about Irene

Everything you need to know about Irene vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Irene vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Irene vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Irene vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Irene. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Irene in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $94 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Irene rentals

At Expedia, we put the best Irene vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Irene rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Irene vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Irene. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Can I find vacation rentals in Irene?

Yes, we offer vacation rentals near the most popular points of interest in Irene, or you can select a secluded option if you'd like a relaxing place to stay.

What's the top vacation rental in Irene?

Charming Lake House within Walking Distance from Lake: This vacation home rental outside of Irene is located on a lake and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games.

What’s there to see and do in Irene?

While you're exploring the area, Fantle Memorial Park and Lincoln Park are a couple of picturesque spots to get outside and enjoy nature. Mount Marty College and Fox Run Plaza are a couple of places you'll find in the larger area.

What are vacation rentals like in Irene?

Vacation rentals are privately owned accommodations you can stay in for several days or more in Irene. Vacation rentals offer extras such as WiFi and washers and dryers so you'll have all the comforts of home. If you're concerned about cleanliness, a vacation rental can offer a sense of safety away from shared hotel elevators and lobbies packed with people while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental a popular option for a small group gathering.