Jeff-Vander-Lou Vacations from $315

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Your Jeff-Vander-Lou Vacation

Jeff-Vander-Lou is calling! Whatever type of escape you have in mind, you can see and experience the best of this neighborhood with a Jeff-Vander-Lou vacation package. Some popular nearby attractions to visit during your trip to Jeff-Vander-Lou include Busch Stadium, Gateway Arch and Dome at America’s Center. Stop daydreaming and start doing. When it's time to lock in your next vacation to Jeff-Vander-Lou, Expedia is here to help.

The Latest Jeff-Vander-Lou Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Principal Hotel

The Principal Hotel

3.5 out of 5
Price was $454, price is now $315 per person
$315
per person
Dec 4 - Dec 7
found 1 day ago
Roundtrip non-stop flight included
Seattle (SEA) to St. Louis (STL)
9.8/10 Exceptional! (126 reviews)
staf went above and beyond to make sure our trip was the best

Reviewed on Sep 1, 2025

White House at Grand Central

White House at Grand Central

4 out of 5
Grand Center
Price was $765, price is now $573 per person
$573
per person
Oct 14 - Oct 19
found 11 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
8.6/10 Excellent! (116 reviews)
The property is in a Safe neighborhood.

Reviewed on Sep 7, 2025

The West End

The West End

2 out of 5
Central West End
Price was $701, price is now $532 per person
$532
per person
Oct 14 - Oct 19
found 11 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
8.4/10 Very Good! (291 reviews)
Great side of town. Quiet

Reviewed on Sep 6, 2025

Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
Price was $767, price is now $596 per person
$596
per person
Oct 17 - Oct 20
found 16 hours ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
8.2/10 Very Good! (763 reviews)
I booked online and paid via the app. When I arrived on site they explained they had overbooked and had no rooms available. The staff was amazing and went above and beyond and secured a room at another location. Thank you to the staff for taking care of us.

Reviewed on Jul 26, 2025

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
Central West End
Save 100% on your flight
Price was $1,260, price is now $991 per person
$991
per person
Oct 14 - Oct 19
found 11 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
9/10 Wonderful! (1,011 reviews)
Great and family friendly!! Would stay again!

Reviewed on Sep 8, 2025

Where to stay in Jeff-Vander-Lou

Find the best Jeff-Vander-Lou areas and neighborhoods for the activities you enjoy most. Learn more about Jeff-Vander-Lou
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

3 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

Jeff-Vander-Lou Hotel Deals

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $143 total per night from Sep 14 to Sep 15
$143 total
Sep 14 - Sep 15
Total with taxes and fees
Hollywood Casino & Hotel St. Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $140 total per night from Sep 28 to Sep 29
$140 total
Sep 28 - Sep 29
Total with taxes and fees
Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $147 total per night from Oct 2 to Oct 3
$147 total
Oct 2 - Oct 3
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
See all 1,752 properties in Jeff-Vander-Lou
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Jeff-Vander-Lou

Busch Stadium

Busch Stadium

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.

Busch Stadium
St. Louis Union Station

St. Louis Union Station

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed theater scene or attend a baseball game.

St. Louis Union Station
Gateway Arch showing a city, a skyscraper and skyline

Gateway Arch

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

$24
per adult
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

$169
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
Step into the shadows and discover the haunting tales of our city's past.

St. Louis Ghosts: Gateway Ghouls and Hauntings

$26
per adult
100% of travellers recommend
St. Louis Ghosts: Gateway Ghouls and Hauntings
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.