Mayesville Vacations from $808

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The Latest Mayesville vacation packages

Price found within the past 48 hours. Click for updated prices.
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

3 out of 5
Price was $863, price is now $808 per person
$808
per person
Apr 19 - Apr 22
found 24 hours ago
Roundtrip flight included
New York (LGA) to Florence (FLO)
8.6/10 Excellent! (701 reviews)
Room was large such a nice space, it includes microwave and refrigerator, but unfortunately it didn’t keep my food cold. I did report this when checking out. Staff is very helpful and great customer service. Offer discount but using Expedia or 3rs party was unable to process. Overall I would definitely stay again.

Reviewed on Feb 22, 2026

The Mantissa Hotel

The Mantissa Hotel

3 out of 5
Price was $1,014, price is now $956 per person
$956
per person
Apr 19 - Apr 22
found 24 hours ago
Roundtrip flight included
New York (LGA) to Florence (FLO)
9.2/10 Wonderful! (274 reviews)
Excellent and accommodating staff. Great and spacious room. We would definitely return.

Reviewed on Nov 23, 2025

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20

3 out of 5
Price was $951, price is now $897 per person
$897
per person
Apr 19 - Apr 22
found 24 hours ago
Roundtrip flight included
New York (LGA) to Florence (FLO)
9.2/10 Wonderful! (590 reviews)
The room was very comfortable and the shower was one of the best we've had in a hotel property. All the staff were very friendly and helpful. Breakfast was excellent with a lot of choices and the attendant kept the items well stocked. We would definitely stay here again.

Reviewed on Mar 2, 2026

Americas Best Value Inn Bishopville

Americas Best Value Inn Bishopville

2 out of 5
Price was $881, price is now $833 per person
$833
per person
Apr 19 - Apr 22
found 24 hours ago
Roundtrip flight included
New York (LGA) to Florence (FLO)
7.2/10 Good! (92 reviews)
The room smelled clean, looked clean and I found no bed bugs. To look at it, we were not sure about our choice. But the wife and I were very pleased. If in the area, we will definitely stay there again.

Reviewed on Oct 27, 2025

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3 out of 5
Price was $934, price is now $886 per person
$886
per person
Apr 19 - Apr 22
found 24 hours ago
Roundtrip flight included
New York (LGA) to Florence (FLO)
9/10 Wonderful! (763 reviews)
There were toe nail clipping on the carpet

Reviewed on Mar 3, 2026

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Mayesville Hotel Deals

Woodspring Suites Sumter Near Shaw Afb

Woodspring Suites Sumter Near Shaw Afb

2.5 out of 5
2715 Broad Street Sumter SC
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $133 total per night from Apr 5 to Apr 6
$133 total
Apr 5 - Apr 6
Total with taxes and fees
8.2/10 Very Good! (176 reviews)
Did not use

Reviewed on Mar 2, 2026

Woodspring Suites Sumter Near Shaw Afb
SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

2.5 out of 5
2816 Paxville Highway Manning SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $99 total per night from Mar 8 to Mar 9
$99 total
Mar 8 - Mar 9
Total with taxes and fees
8.6/10 Excellent! (1,003 reviews)
Nice hotel. Clean. Good location.

Reviewed on Mar 5, 2026

SureStay Hotel by Best Western Manning
Hyatt Place Sumter / Downtown

Hyatt Place Sumter / Downtown

3 out of 5
18 N Main St Sumter SC
Fully refundableReserve now, pay when you stay
$196 nightly
The price is $220 total per night from Mar 20 to Mar 21
$220 total
Mar 20 - Mar 21
Total with taxes and fees
9.2/10 Wonderful! (906 reviews)
My complaint is not with the hotel....it was excellent and the staff was superb. Hotels.com made this reservation for ? plus ? for cancellation insurance. The cancellation insurance was supposed to be ? but when I asked Hotels.com said the price was for two days since I checked in on the 25th and ...

Reviewed on Feb 28, 2026

Hyatt Place Sumter / Downtown
See all 77 properties in Mayesville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mayesville Vacation Packages

Mayesville Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Florence Regional Airport (FLO)
Population
730

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Frequently asked questions

How much does a Mayesville vacation package cost?
You'll find cheap prices from $808 on Expedia for your Mayesville getaway. However, a range of factors like the length of stay, the season and your choice of hotel will influence how much your vacation to Mayesville costs.
What are the cheapest months to go to Mayesville?
You can usually find lower rates and greater availability in January, March and September. Browse our cheap Mayesville vacation packages and you could score some excellent off-season deals.
How many days is enough for Mayesville?
With a well-organized itinerary, you can easily visit the top Mayesville sights in a few days. But if you want to explore off the beaten track or go on day tours, consider booking your Mayesville vacation for longer.
How to find the best Mayesville package deals?
Use Expedia's filters to find some fabulous Mayesville package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or look for Mayesville package deals in the off-peak season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to book your vacation package as early as possible.
Is it cheaper to book a Mayesville vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking flights and hotels separately. Better still, you can tailor your Mayesville escape to match your exact needs. Choose your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Mayesville?
Secure incredible discounts by booking your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for an impromptu Mayesville escape.
Does Expedia offer Book Now, Pay Later Mayesville vacation packages?
If you're anything like us, you love discovering new places but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Mayesville vacation over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.