Mayesville Vacations from $1,072

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The Latest Mayesville vacation packages

Price found within the past 48 hours. Click for updated prices.
Motel 6 Florence, SC

Motel 6 Florence, SC

2 out of 5
Price was $1,479, price is now $1,072 per person
$1,072
per person
Jun 7 - Jun 13
found 17 hours ago
Roundtrip non-stop flight included
Myrtle Beach (MYR) to Florence (FLO)
6.2/10 (682 reviews)
More dirty than I prefer

Reviewed on Apr 7, 2026

Studio 6 Florence , SC

Studio 6 Florence , SC

2.5 out of 5
Price was $1,501, price is now $1,073 per person
$1,073
per person
Jun 7 - Jun 13
found 17 hours ago
Roundtrip non-stop flight included
Myrtle Beach (MYR) to Florence (FLO)
3.6/10 (7 reviews)
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

3 out of 5
Price was $1,581, price is now $1,138 per person
$1,138
per person
Jun 7 - Jun 13
found 17 hours ago
Roundtrip non-stop flight included
Myrtle Beach (MYR) to Florence (FLO)
8.6/10 Excellent! (725 reviews)
The front desk staff and the breakfast staff were always very friendly. My room was clean and well stocked with towels and coffee/tea condiments upon my arrival. I wasn’t aware though that I had to request my room to be cleaned on a daily basis. For this reason alone, I’ll think twice before staying again.

Reviewed on Apr 25, 2026

Residence Inn Marriott Florence

Residence Inn Marriott Florence

3 out of 5
Price was $1,767, price is now $1,301 per person
$1,301
per person
Jun 7 - Jun 13
found 17 hours ago
Roundtrip non-stop flight included
Myrtle Beach (MYR) to Florence (FLO)
8.8/10 Excellent! (536 reviews)
The breakfast staff was very friendly, and the breakfast buffet was terrific.

Reviewed on Apr 21, 2026

Raceway Inn

Raceway Inn

2.5 out of 5
Price was $1,513, price is now $1,114 per person
$1,114
per person
Jun 7 - Jun 13
found 17 hours ago
Roundtrip non-stop flight included
Myrtle Beach (MYR) to Florence (FLO)
5.8/10 (50 reviews)
Not clean refrigerator was dirty no lamp shades dusty dirty ac unit very unprofessional

Reviewed on Apr 27, 2025

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Mayesville Hotel Deals

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

2.5 out of 5
2816 Paxville Highway Manning SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $110 total per night from May 24 to May 25
$110 total
May 24 - May 25
Total with taxes and fees
8.6/10 Excellent! (1,000 reviews)
clean and nice place.

Reviewed on Apr 28, 2026

SureStay Hotel by Best Western Manning
Woodspring Suites Sumter Near Shaw Afb

Woodspring Suites Sumter Near Shaw Afb

2.5 out of 5
2715 Broad Street Sumter SC
$144 nightly
The price is $161 total per night from May 3 to May 4
$161 total
May 3 - May 4
Total with taxes and fees
8.2/10 Very Good! (200 reviews)
Will definitely be back! Full size fridge, microwave and cook top. Extremely well maintained and clean!!

Reviewed on Apr 28, 2026

Woodspring Suites Sumter Near Shaw Afb
Hyatt Place Sumter / Downtown

Hyatt Place Sumter / Downtown

3 out of 5
18 N Main St Sumter SC
Fully refundableReserve now, pay when you stay
$207 nightly
The price is $232 total per night from May 25 to May 26
$232 total
May 25 - May 26
Total with taxes and fees
9.2/10 Wonderful! (916 reviews)
Everything thing was great.

Reviewed on Apr 11, 2026

Hyatt Place Sumter / Downtown
See all 76 properties in Mayesville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mayesville Vacation Packages

Mayesville Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Florence Regional Airport (FLO)
Population
730

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Frequently asked questions

How much does a Mayesville vacation package cost?
You'll find cheap prices from $1,072 on Expedia for your Mayesville getaway. However, a range of factors like the length of stay, the season and your choice of hotel will influence how much your vacation to Mayesville costs.
What are the cheapest months to go to Mayesville?
You can usually find lower rates and greater availability in January, March and September. Browse our cheap Mayesville vacation packages and you could score some excellent off-season deals.
How many days is enough for Mayesville?
With a well-organized itinerary, you can easily visit the top Mayesville sights in a few days. But if you want to explore off the beaten track or go on day tours, consider booking your Mayesville vacation for longer.
How to find the best Mayesville package deals?
Use Expedia's filters to find some fabulous Mayesville package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or look for Mayesville package deals in the off-peak season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to book your vacation package as early as possible.
Is it cheaper to book a Mayesville vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking flights and hotels separately. Better still, you can tailor your Mayesville escape to match your exact needs. Choose your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Mayesville?
Secure incredible discounts by booking your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for an impromptu Mayesville escape.
Does Expedia offer Book Now, Pay Later Mayesville vacation packages?
If you're anything like us, you love discovering new places but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Mayesville vacation over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.